Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Jianbin Tang"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Global mortality data indicates cancer as the second-leading cause of death worldwide. Therefore, there’s a pressing need to innovate effective treatments to address this significant medical and societal challenge. In recent years, X-ray-i
Externí odkaz:
https://doaj.org/article/463b27f90505436a847df3764a3c49e9
Autor:
Shasha Yao, Yi Wang, Qian Tang, Yujie Yin, Yu Geng, Lei Xu, Shifu Liang, Jiajia Xiang, Jiaqi Fan, Jianbin Tang, Jian Liu, Shiqun Shao, Youqing Shen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Existing strategies use bifunctional chimaeras to mediate extracellular protein degradation. However, these strategies rely on specific lysosome-trafficking receptors to facilitate lysosomal delivery, which may raise resistance concerns due
Externí odkaz:
https://doaj.org/article/8e39df289614425d8308c2f60e512fc4
Publikováno v:
Journal of Rock Mechanics and Geotechnical Engineering, Vol 15, Iss 12, Pp 3316-3327 (2023)
To address the problems of strain localization, the exact Mohr-Coulomb (MC) model is used based on second-order cone programming (mpcFEM-SOCP) in the framework of micropolar continuum finite element method. Using the uniaxial compression test, we foc
Externí odkaz:
https://doaj.org/article/0e50a1ef7294483bacaf888ce317145f
Autor:
Jiajia Xiang, Kexin Liu, Hongxia Xu, Zhihao Zhao, Ying Piao, Shiqun Shao, Jianbin Tang, Youqing Shen, Zhuxian Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 29, Pp n/a-n/a (2023)
Abstract Chemo‐immunotherapy has made significant progress in cancer treatment. However, the cancer cell self‐defense mechanisms, including cell cycle checkpoint and programmed cell death‐ligand 1 (PD‐L1) upregulation, have greatly hindered t
Externí odkaz:
https://doaj.org/article/b7b3b1f1cb6b48e89e6504c39aefa975
Autor:
Chao Yu, Dongdong Li, Chenggui Wang, Kaishun Xia, Jingkai Wang, Xiaopeng Zhou, Liwei Ying, Jiawei Shu, Xianpeng Huang, Haibin Xu, Bin Han, Qixin Chen, Fangcai Li, Jianbin Tang, Chengzhen Liang, Nigel Slater
Publikováno v:
Bioactive Materials, Vol 6, Iss 10, Pp 3568-3579 (2021)
Cell transplantation has been proved the promising therapeutic effects on intervertebral disc degeneration (IVDD). However, the increased levels of reactive oxygen species (ROS) in the degenerated region will impede the efficiency of human adipose-de
Externí odkaz:
https://doaj.org/article/34ec63e8de864c3ab1353cf746a83b3a
Autor:
Jing Liu, Zhihao Zhao, Nasha Qiu, Quan Zhou, Guowei Wang, Haiping Jiang, Ying Piao, Zhuxian Zhou, Jianbin Tang, Youqing Shen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Some chemotherapeutic drugs, such as doxorubicin, induce immunogenic cell death (ICD) and promote anti-tumor immune responses. Here the authors report that the histone demethylase inhibitor 5-carboxy-8-hydroxyquinoline (IOX1) reduces the expression o
Externí odkaz:
https://doaj.org/article/9c13235dc1e945df90f7c6920d76d06e
Autor:
Jiajia Xiang, Yihuai Shen, Yifan Zhang, Xin Liu, Quan Zhou, Zhuxian Zhou, Jianbin Tang, Shiqun Shao, Youqing Shen
Publikováno v:
Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)
Abstract The cancer drug delivery process involves a series of biological barriers, which require the nanomedicine to exhibit different, even opposite properties for high therapeutic efficacy. The prevailing design philosophy, i.e., integrating these
Externí odkaz:
https://doaj.org/article/48f72143432e43c8bfb52c8381662cff
Autor:
Doudou Hu, Wei Zhang, Jiajia Xiang, Dongdong Li, Yong Chen, Pengcheng Yuan, Shiqun Shao, Zhuxian Zhou, Youqing Shen, Jianbin Tang
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100284- (2022)
Immune checkpoint blockade (ICB) therapies that target programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) pathway are currently used for the treatment of various cancer types. However, low response rates of ICB remain the major iss
Externí odkaz:
https://doaj.org/article/765287b612b74994a28cbc07b291083d
Publikováno v:
Applied Sciences, Vol 12, Iss 12, p 6049 (2022)
This paper presents a scratch detection system based on a cubic Bezier curve fitting using a linear scan camera. The objective was to detect the scratch defects of an aluminum flat tube stably in real-time under complex uncertain background noise. To
Externí odkaz:
https://doaj.org/article/e525f7fb41dd4f76a64cb668741f9b97
Autor:
Subhrajit Roy, Isabell Kiral, Mahtab Mirmomeni, Todd Mummert, Alan Braz, Jason Tsay, Jianbin Tang, Umar Asif, Thomas Schaffter, Mehmet Eren Ahsen, Toshiya Iwamori, Hiroki Yanagisawa, Hasan Poonawala, Piyush Madan, Yong Qin, Joseph Picone, Iyad Obeid, Bruno De Assis Marques, Stefan Maetschke, Rania Khalaf, Michal Rosen-Zvi, Gustavo Stolovitzky, Stefan Harrer
Publikováno v:
EBioMedicine, Vol 66, Iss , Pp 103275- (2021)
Background: Assistive automatic seizure detection can empower human annotators to shorten patient monitoring data review times. We present a proof-of-concept for a seizure detection system that is sensitive, automated, patient-specific, and tunable t
Externí odkaz:
https://doaj.org/article/a63bf3e7593244738d97a0a1e3a48f62