Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jianbiao Zheng"'
Autor:
Mark Klinger, Francois Pepin, Jen Wilkins, Thomas Asbury, Tobias Wittkop, Jianbiao Zheng, Martin Moorhead, Malek Faham
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141561 (2015)
Monitoring antigen-specific T cells is critical for the study of immune responses and development of biomarkers and immunotherapeutics. We developed a novel multiplex assay that combines conventional immune monitoring techniques and immune receptor r
Externí odkaz:
https://doaj.org/article/5e07b9e6e82e43fdb44cf1bbe5b395fa
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74231 (2013)
In this study, we combined a novel sequencing method, which can identify individual clonotypes based on their unique T cell receptor (TCR) rearrangement, with existing immune assays to characterize antigen-specific T cell responses. We validated this
Externí odkaz:
https://doaj.org/article/3c0b400766774c81a49228d135ae0fd6
Autor:
Yoshitaka Zaimoku, Yasushi Terasaki, Tsutomu Sato, Martin Moorhead, Shinji Nakao, Katherine A. Kong, Naoki Takezako, Kenji Yokoyama, Hiroyuki Takamatsu, Hideo Yagi, Ryoichi Murata, Malek Faham, Morio Matsumoto, Rachel K Wee, Shigeki Ito, Victoria Carlton, Kinya Ohata, Toshiro Kurokawa, Takashi Yoshida, Toshihiro Miyamoto, Kosei Matsue, Jianbiao Zheng
Publikováno v:
British Journal of Haematology. 183:664-668
Autor:
Kosei Matsue, Tomotaka Yoshida, Malek Faham, Tsutomu Sato, Martin Moorhead, Shigeki Ito, Victoria Carlton, Hiroyuki Takamatsu, Jianbiao Zheng, Toshiro Kurokawa, Shinji Nakao, Ryoichi Murata, Kinya Ohata, Naoki Takezako, Morio Matsumoto, Hideo Yagi, Katherine A. Kong, Kozue Yokoyama, Yasushi Terasaki, Toshihiro Miyamoto
Publikováno v:
Annals of Oncology
Background Most patients with multiple myeloma (MM) are considered to be incurable, and relapse owing to minimal residual disease (MRD) is the main cause of death among these patients. Therefore, new technologies to assess deeper response are require
Autor:
Kojo S.J. Elenitoba-Johnson, M Faham, Sherrie L. Perkins, David W. Bahler, Mark Klinger, Jianbiao Zheng
Publikováno v:
Leukemia. 30:1055-1061
Chronic lymphocytic leukemia (CLL) develops from CLL-like monoclonal B-cell lymphocytosis (MBL) which represents a low-level asymptomatic expansion of cells that phenotypically resemble CLL. Although antigen selection plays a key role during CLL deve
Autor:
Aaron C Logan, David B. Miklos, Jianbiao Zheng, James L. Zehnder, Amna Waqar, Malek Faham, Mark R. Krampf, Balasubramanian Narasimhan, Carol D. Jones, Bing Zhang, Victoria Carlton, Martin Moorhead
Publikováno v:
Leukemia
Quantification of minimal residual disease (MRD) following allogeneic hematopoietic cell transplantation (allo-HCT) predicts post-transplant relapse in patients with chronic lymphocytic leukemia (CLL). We utilized an MRD-quantification method that am
Autor:
Jianbiao Zheng, Julie Wilhelmy, Michael N. Mindrinos, Sujatha Krishnakumar, Malek Faham, Ronald W. Davis
Publikováno v:
Proceedings of the National Academy of Sciences. 105:9296-9301
We developed a robust and reproducible methodology to amplify human sequences in parallel for use in downstream multiplexed sequence analyses. We call the methodology SMART (Spacer Multiplex Amplification Reaction), and it is based, in part, on padlo
Autor:
Harlan Robins, Jianbiao Zheng, James S. Ireland, Martin Moorhead, Emily Baechler‐Gillespie, Malek Faham, Robert D. Inman, Marissa Vignali, Victoria Carlton, Mark Klinger, Thomas Asbury, Ryan O. Emerson, Francois Pepin
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 69(4)
Objective Ankylosing spondylitis (AS), a chronic inflammatory disorder, has a notable association with HLA–B27. One hypothesis suggests that a common antigen that binds to HLA–B27 is important for AS disease pathogenesis. This study was undertake
Autor:
Kieron Dunleavy, Malek Faham, Louis M. Staudt, Stefania Pittaluga, Katherine A. Kong, Martin Moorhead, Catherine Lai, Seth M. Steinberg, Elaine S. Jaffe, Thomas D. Willis, Clara C. Chen, Mark Roschewski, Jianbiao Zheng, Margaret Shovlin, Wyndham H. Wilson, Francois Pepin
Publikováno v:
The Lancet. Oncology. 16(5)
Diffuse large-B-cell lymphoma is curable, but when treatment fails, outcome is poor. Although imaging can help to identify patients at risk of treatment failure, they are often imprecise, and radiation exposure is a potential health risk. We aimed to
Autor:
Francois Pepin, Malek Faham, Martin Moorhead, Mark Klinger, Jen Wilkins, Jianbiao Zheng, Tobias Wittkop, Thomas Asbury
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141561 (2015)
PLoS ONE
PLoS ONE
Monitoring antigen-specific T cells is critical for the study of immune responses and development of biomarkers and immunotherapeutics. We developed a novel multiplex assay that combines conventional immune monitoring techniques and immune receptor r