Zobrazeno 1 - 10
of 166
pro vyhledávání: '"JianXing Yin"'
Autor:
Jianxing Yin, Xiefeng Wang, Xin Ge, Fangshu Ding, Zhumei Shi, Zehe Ge, Guang Huang, Ningwei Zhao, Dongyin Chen, Junxia Zhang, Sameer Agnihotri, Yuandong Cao, Jing Ji, Fan Lin, Qianghu Wang, Qigang Zhou, Xiuxing Wang, Yongping You, Zhimin Lu, Xu Qian
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Temozolomide (TMZ) is a standard treatment for glioblastoma (GBM) patients. However, TMZ has moderate therapeutic effects due to chemoresistance of GBM cells through less clarified mechanisms. Here, we demonstrate that TMZ-derived 5-aminoimi
Externí odkaz:
https://doaj.org/article/222d6b61d74e4688bf6df0cc6f4060e8
Autor:
Jianxing Yin, Fangshu Ding, Zhangchun Cheng, Xin Ge, Yanhui Li, Ailiang Zeng, Junxia Zhang, Wei Yan, Zhumei Shi, Xu Qian, Yongping You, Zhiliang Ding, Jing Ji, Xiefeng Wang
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-12 (2023)
Abstract Long noncoding RNAs (lncRNAs) are involved in glioma initiation and progression. Glioma stem cells (GSCs) are essential for tumor initiation, maintenance, and therapeutic resistance. However, the biological functions and underlying mechanism
Externí odkaz:
https://doaj.org/article/99f11da15a63462d9198ce0ec0f0d457
Autor:
Xin Ge, Mengdie Li, Guo‐Xin Song, Zhixiang Zhang, Jianxing Yin, Zehe Ge, Zhumei Shi, Ling‐Zhi Liu, Bing‐Hua Jiang, Xu Qian, Hua Shen
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Cr(VI) is broadly applied in industry. Cr(VI) exposure places a big burden on public health, thereby increasing the risk of lung squamous cell carcinoma (LUSC). The mechanisms underlying Cr(VI)‐induced LUSC remain largely elusive. Here, we
Externí odkaz:
https://doaj.org/article/f7e632d741dc495897d557946aa5f81f
Autor:
JianXing Yin, ZhuMei Shi, WenJin Wei, Chenfei Lu, Yutian Wei, Wei Yan, Rui Li, JunXia Zhang, YongPing You, XieFeng Wang
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Glucose metabolic reprogramming is a significant hallmark of malignant tumors including GBM. Previous studies suggest that microRNAs play key roles in modulating this process in GBM cells. miR-181b acts as a tumor suppressor miRNA
Externí odkaz:
https://doaj.org/article/451822e6911749b5be910185049f4ef9
Autor:
Chenfei Lu, Yutian Wei, Xiefeng Wang, Zhuoran Zhang, Jianxing Yin, Wentao Li, Lijiu Chen, Xiao Lyu, Zhumei Shi, Wei Yan, Yongping You
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-19 (2020)
Abstract Background Accumulating evidence shows that long noncoding RNAs (lncRNAs) are important regulator molecules involved in diverse biological processes. Acquired drug resistance is a major challenge in the clinical treatment of glioblastoma (GB
Externí odkaz:
https://doaj.org/article/0478454b0efe490085728f5f7fd46931
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate
Externí odkaz:
https://doaj.org/article/7459fb0606e84f01ae1c09a016e120de
Publikováno v:
EBioMedicine, Vol 42, Iss , Pp 238-251 (2019)
Background: Although temozolomide (TMZ) resistance is a significant clinical problem in glioblastoma (GBM), its underlying molecular mechanisms are poorly understood. In this study, we identified the role of exosomal microRNAs (miRNAs) from TMZ-resis
Externí odkaz:
https://doaj.org/article/8ba8a89453534d148e1864f02481a522
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 1, Pp 233-245 (2018)
Background/Aims: Glioma is one of the most devasting tumors and confers dismal prognosis. Long noncoding RNAs(lncRNAs) have emerged as important regulators in various tumors including glioma. A classic lncRNA-H19, which is found to be highly expresse
Externí odkaz:
https://doaj.org/article/0eadcc7c7a034022a7d94769339df144
Autor:
Mengjie Zhao, Yanhui Li, Chenfei Lu, Fangshu Ding, Miao Xu, Xin Ge, Mengdie Li, Zhen Wang, Jianxing Yin, Junxia Zhang, Xiefeng Wang, Zehe Ge, Hong Xiao, Yong Xiao, Hongyi Liu, Wentao Liu, Yuandong Cao, Qianghu Wang, Yongping You, Xiuxing Wang, Kun Yang, Zhumei Shi, Xu Qian
Publikováno v:
Cancer Research. 83:1094-1110
Radiotherapy is a major component of standard-of-care treatment for gliomas, the most prevalent type of brain tumor. However, resistance to radiotherapy remains a major concern. Identification of mechanisms governing radioresistance in gliomas could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f677fa12c5fb8a46f5da1c46fb1437c5
https://doi.org/10.1158/0008-5472.can-22-3083
https://doi.org/10.1158/0008-5472.can-22-3083
Autor:
Xu Qian, Zhumei Shi, Kun Yang, Xiuxing Wang, Yongping You, Qianghu Wang, Yuandong Cao, Wentao Liu, Hongyi Liu, Yong Xiao, Hong Xiao, Zehe Ge, Xiefeng Wang, Junxia Zhang, Jianxing Yin, Zhen Wang, Mengdie Li, Xin Ge, Miao Xu, Fangshu Ding, Chenfei Lu, Yanhui Li, Mengjie Zhao
Radiotherapy is a major component of standard-of-care treatment for gliomas, the most prevalent type of brain tumor. However, resistance to radiotherapy remains a major concern. Identification of mechanisms governing radioresistance in gliomas could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0769e7b63f0842ba8b701d14927a9b50
https://doi.org/10.1158/0008-5472.c.6487387.v2
https://doi.org/10.1158/0008-5472.c.6487387.v2
