Zobrazeno 1 - 10
of 368
pro vyhledávání: '"JianQiang Guo"'
Autor:
Yunyun Li, Xuelian Yang, Tao Han, Jiawei Zhou, Yafeng Liu, Jianqiang Guo, Ziqin Liu, Ying Bai, Yingru Xing, Xuansheng Ding, Jing Wu, Dong Hu
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102095- (2024)
Background: The immune status is closely linked to cancer progression, metastasis, and prognosis. Lipid metabolism, crucial for reshaping immune status, plays a key role in regulating the advancement of lung adenocarcinoma (LUAD) and deserves further
Externí odkaz:
https://doaj.org/article/80317cf442284c7995e61e36305a3971
Autor:
Yafeng Liu, Tao Han, Zhi Xu, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Yingru Xing, Deyong Ge, Ying Bai, Dong Hu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Objective This study aimed to assess the functions of cell division cycle protein 45 (CDC45) in Non-small cell lung cancer (NSCLC) cancer and its effects on stemness and metastasis. Methods Firstly, differentially expressed genes related to
Externí odkaz:
https://doaj.org/article/3baf555ffb004dbfaacc4dbdf27693c1
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundTraumatic brain injury (TBI) causes neuronal cell damage and dysfunction. According to previous studies, daphnetin (Dap) has a protective effect in neurological injury. However, the in vivo bioavailability of daphnetin is not high. The purp
Externí odkaz:
https://doaj.org/article/891e501c84774260b90bd2e7d1e7bf5c
Autor:
Peihua Niu, Zhenlu Sun, Ruiqing Zhang, Yiming Zhao, Fengyu Tian, Ping Cheng, Hongmei Zheng, Jianqiang Guo, Meng Zhang, Xuejun Ma, Ji Wang
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundThe COVID-19 pandemic underscored the critical importance of biosafety in microbiology laboratories worldwide. In response, China has ramped up its efforts to enhance biosafety measures within its Centers for Disease Control and Prevention
Externí odkaz:
https://doaj.org/article/fcfa747b674d43888aa4dab9b8315495
Autor:
Rui Miao, Zhi Xu, Tao Han, Yafeng Liu, Jiawei Zhou, Jianqiang Guo, Yingru Xing, Ying Bai, Zhonglei He, Jing Wu, Wenxin Wang, Dong Hu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
ObjectiveBy utilizing machine learning, we can identify genes that are associated with recurrence, invasion, and tumor stemness, thus uncovering new therapeutic targets.MethodsTo begin, we obtained a gene set related to recurrence and invasion from t
Externí odkaz:
https://doaj.org/article/fe2ae54b49be4e57b19b9f420b45fa2b
Autor:
Ying Bai, Tao Han, Yunjia Dong, Chao Liang, Lu Gao, Yafeng Liu, Jiawei Zhou, Jianqiang Guo, Deyong Ge, Jing Wu, Dong Hu
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Background Cancer-associated fibroblasts (CAFs) play a crucial role in the tumor microenvironment of lung adenocarcinoma (LUAD) and are often associated with poorer clinical outcomes. This study aimed to screen for CAF-specific genes that co
Externí odkaz:
https://doaj.org/article/f2b705546e164e1aa15e60cdc8e34017
Autor:
Yafeng Liu, Tao Han, Rui Miao, Jiawei Zhou, Jianqiang Guo, Zhi Xu, Yingru Xing, Ying Bai, Jing Wu, Dong Hu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Objection Investigating the key genes and mechanisms that influence stemness in lung adenocarcinoma. Methods First, consistent clustering analysis was performed on lung adenocarcinoma patients using stemness scoring to classify them. Subsequ
Externí odkaz:
https://doaj.org/article/40e2617f2f994076939c5a5e62ed8ee3
Autor:
Tao Han, Yafeng Liu, Jiawei Zhou, Jianqiang Guo, Yingru Xing, Jun Xie, Ying Bai, Jing Wu, Dong Hu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The invasive capacity of lung adenocarcinoma (LUAD) is an important factor influencing patients’ metastatic status and survival outcomes. However, there is still a lack of suitable biomarkers to evaluate tumor invasiveness. LUAD molecular
Externí odkaz:
https://doaj.org/article/dde9354c96724586a71ef3784eb434b0
Autor:
Yafeng Liu, Tao Han, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Zhi Xu, Yingru Xing, Ying Bai, Dong Hu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background The occurrence of epithelial-mesenchymal transition (EMT) and immune evasion is considered to contribute to poor prognosis in lung adenocarcinoma (LUAD). Therefore, this study aims to explore the key oncogenes that promote EMT and
Externí odkaz:
https://doaj.org/article/0c12cef9c507428a8846cb4920f956ed
Autor:
Tao Han, Yafeng Liu, Jing Wu, Ying Bai, Jiawei Zhou, Chunxiao Hu, Wenting Zhang, Jianqiang Guo, Qingsen Wang, Dong Hu
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract In lung adenocarcinoma (LUAD), immune heterogeneity of hot and cold tumors has been recognized as one of the major factors affecting immunotherapy and other common treatments. However, there is still a lack of biomarkers that can effectively
Externí odkaz:
https://doaj.org/article/d811b69578d94679919ed643bcb7354c