Zobrazeno 1 - 5
of 5
pro vyhledávání: '"JianGen Gong"'
Autor:
Dan Hui Wang, Janaki Verraraghavan, Michael G. Brattain, Jiangen Gong, Lu-Zhe Sun, James K V Willson, Elizabeth Zborowska
Publikováno v:
Journal of Biological Chemistry. 274:12840-12847
Ectopic expression of the alpha5 integrin subunit in cancer cells with little or no endogenous expression of this integrin often results in reduced proliferation as well as reduced malignancy. We now show that inhibition resulting from ectopic expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5c63c6159d8c1b44808b44708f9180
https://doi.org/10.1074/jbc.274.18.12840
https://doi.org/10.1074/jbc.274.18.12840
Autor:
Lu Zhe Sun, DanHui Wang, Michael G. Brattain, Thomas M. Birkenmeier, Jiangen Gong, Guo-hao Zhou
Publikováno v:
Journal of Biological Chemistry. 270:14154-14159
Transforming growth factor beta (TGF-beta) has been extensively studied as an exogenous agent that stimulates the expression of extracellular matrix proteins and their cell-surface integrin receptors in a variety of cell types. However, the recent de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a4c61a9e7ccefff85adba7d2fb8533
https://doi.org/10.1074/jbc.270.23.14154
https://doi.org/10.1074/jbc.270.23.14154
Publikováno v:
Cancer research. 63(12)
We examined transforming growth factor-beta 1 (TGF-beta 1) effects on cell cycle progression of human colon carcinoma FET cells. TGF-beta 1 inhibited DNA synthesis and cyclin-dependent kinase (CDK) activity after release from growth arrest in associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8270228f24aedb38e5aaffa885efe188
https://pubmed.ncbi.nlm.nih.gov/12810668
https://pubmed.ncbi.nlm.nih.gov/12810668
Autor:
JianGen Gong, Massimo Levrero, William G. Kaelin, Jean Y. J. Wang, Hong-Qiong Yang, Gerry Melino, Antonio Costanzo
Cancer chemotherapeutic agents such as cisplatin exert their cytotoxic effect by inducing DNA damage and activating programmed cell death (apoptosis). The tumour-suppressor protein p53 is an important activator of apoptosis. Although p53-deficient ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c4ece25b496aa3a4992ff03ce85100
http://hdl.handle.net/11573/438336
http://hdl.handle.net/11573/438336
Publikováno v:
The Journal of biological chemistry. 273(3)
The alpha 5 alpha 1 integrin, a fibronectin receptor, has been implicated in the control of cell growth and the regulation of gene expression. We report that disruption of ligation between alpha 5 alpha 1 and fibronectin by integrin alpha 5 subunit o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5094cba4b80ba323c1144995ec6d5b
https://pubmed.ncbi.nlm.nih.gov/9430710
https://pubmed.ncbi.nlm.nih.gov/9430710