Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jian-yong Sun"'
Autor:
Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Chao Bi, Lin-Juan Du, Yuan Liu, Lu-Jun Zhou, Ting Liu, Shuo Xu, Chao-Ji Shi, Hong Zhu, Yong-Li Wang, Jian-Yong Sun, Yan Liu, Wu-Chang Zhang, Hai-Xia Lu, Yi-Hua Wang, Qiang Feng, Fu-Xiang Chen, Chang-Qian Wang, Maurizio S. Tonetti, Ya-Qin Zhu, Huili Zhang, Sheng-Zhong Duan
Publikováno v:
Journal of Advanced Research, Vol 43, Iss , Pp 147-161 (2023)
Introduction: Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but the nature behind this connection is unclear. Dysbiosis of oral microbiota leading to PD is known to aggravate different systematic diseases, but the alterat
Externí odkaz:
https://doaj.org/article/71033037bd794f0dab07ee9d7a79ad79
Autor:
Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Chao Bi, Lin-Juan Du, Yuan Liu, Lu-Jun Zhou, Ting Liu, Shuo Xu, Chao-Ji Shi, Hong Zhu, Yong-Li Wang, Jian-Yong Sun, Yan Liu, Wu-Chang Zhang, Zhiyuan Zhang, Hui-li Zhang, Ya-Qin Zhu, Sheng-Zhong Duan
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The mycobiome is an essential constituent of the human microbiome and is associated with various diseases. However, the role of oral and gut fungi in hypertension (HTN) remains largely unexplored. In this study, saliva, subgingival plaques,
Externí odkaz:
https://doaj.org/article/537dd5e490e04690aad0233584470ae0
Autor:
Lin‐Juan Du, Jian‐Yong Sun, Wu‐Chang Zhang, Yong‐Li Wang, Hong Zhu, Ting Liu, Ming‐Zhu Gao, Chen Zheng, Yu‐Yao Zhang, Yuan Liu, Yan Liu, Shuai Shao, Xue‐Qing Zhang, Qibin Leng, Johan Auwerx, Sheng‐Zhong Duan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background NCOR1 (nuclear receptor corepressor 1) is an essential coregulator of gene transcription. It has been shown that NCOR1 in macrophages plays important roles in metabolic regulation. However, the function of macrophage NCOR1 in response to m
Externí odkaz:
https://doaj.org/article/674bd41bffae467da6ef79a13fe6fa62
Autor:
Jian-Yong Sun, Lin-Juan Du, Xue-Rui Shi, Yu-Yao Zhang, Yuan Liu, Yong-Li Wang, Bo-Yan Chen, Ting Liu, Hong Zhu, Yan Liu, Cheng-Chao Ruan, Zhenji Gan, Hao Ying, Zhinan Yin, Ping-Jin Gao, Xiaoxiang Yan, Ruo-Gu Li, Sheng-Zhong Duan
Publikováno v:
Science Advances. 9
The liver plays a protective role in myocardial infarction (MI). However, very little is known about the mechanisms. Here, we identify mineralocorticoid receptor (MR) as a pivotal nexus that conveys communications between the liver and the heart duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d64ad7ddd1b4321fc85dc43c2b83c2
https://doi.org/10.1126/sciadv.ade4110
https://doi.org/10.1126/sciadv.ade4110
Osteoblast MR deficiency protects against adverse ventricular remodeling after myocardial infarction
Autor:
Yong-Li, Wang, Lan, Bai, Xue-Rui, Shi, Hong, Zhu, Lin-Juan, Du, Yuan, Liu, Xiao-Xin, Ma, Wen-Zhen, Lin, Ting, Liu, Jian-Yong, Sun, Yan, Liu, Xu-Guang, Guo, Lu-Jun, Zhou, Bo-Yan, Chen, Shuai, Shao, Xiao-Qian, Meng, Yu-Lin, Li, Ruo-Gu, Li, Sheng-Zhong, Duan
Publikováno v:
Journal of Molecular and Cellular Cardiology. 167:40-51
Mineralocorticoid receptor (MR) antagonists have been clinically used to treat heart failure. However, the underlying cellular and molecular mechanisms remain incompletely understood.Using osteoblast MR knockout (MRMR deficiency in osteoblasts allevi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e735195b71d2ff035d4674b66dd9ec0
https://doi.org/10.1016/j.yjmcc.2022.03.003
https://doi.org/10.1016/j.yjmcc.2022.03.003
Autor:
Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Chao Bi, Lin-Juan Du, Yuan Liu, Lu-Jun Zhou, Ting Liu, Shuo Xu, Chao-Ji Shi, Hong Zhu, Yong-Li Wang, Jian-Yong Sun, Yan Liu, Wu-Chang Zhang, Zhiyuan Zhang, Hui-li Zhang, Ya-Qin Zhu, Sheng-Zhong Duan
Publikováno v:
Microbiology spectrum.
The mycobiome is an essential constituent of the human microbiome and is associated with various diseases. However, the role of oral and gut fungi in hypertension (HTN) remains largely unexplored. In this study, saliva, subgingival plaques, and feces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fe63f3c00ac0989e794690076f45a6
https://pubmed.ncbi.nlm.nih.gov/36475759
https://pubmed.ncbi.nlm.nih.gov/36475759
Autor:
Ting Liu, Yu‐Lin Li, Lu‐Jun Zhou, Xue‐Nan Sun, Yong‐Li Wang, Lin‐Juan Du, Yuan Liu, Hong Zhu, Bo‐Yan Chen, Jian‐Yong Sun, Yan Liu, Shuo Xu, Hui‐Lin Ye, Shi‐Jia Huang, Xiaoxia Wang, Bin Li, Sheng‐Zhong Duan
Publikováno v:
ImmunologyREFERENCES. 167(1)
Mineralocorticoid receptor (MR) is a classic nuclear receptor and an effective drug target in the cardiovascular system. The function of MR in immune cells such as macrophages and T cells has been increasingly appreciated. The aim of this study was t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb0ab72443f4cdc7580f1aba6a8e004
https://pubmed.ncbi.nlm.nih.gov/35751882
https://pubmed.ncbi.nlm.nih.gov/35751882
Autor:
Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Chao Bi, Lin-Juan Du, Yuan Liu, Lu-Jun Zhou, Ting Liu, Shuo Xu, Chao-Ji Shi, Hong Zhu, Yong-Li Wang, Jian-Yong Sun, Yan Liu, Wu-Chang Zhang, Hai-Xia Lu, Yi-Hua Wang, Qiang Feng, Fu-Xiang Chen, Chang-Qian Wang, Maurizio S. Tonetti, Ya-Qin Zhu, Huili Zhang, Sheng-Zhong Duan
Publikováno v:
Journal of advanced research. 43
Considerable evidence has linked periodontitis (PD) to hypertension (HTN), but the nature behind this connection is unclear. Dysbiosis of oral microbiota leading to PD is known to aggravate different systematic diseases, but the alteration of oral mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d0ee6b6b8a14928e6c52cb966db1331
https://pubmed.ncbi.nlm.nih.gov/36585105
https://pubmed.ncbi.nlm.nih.gov/36585105
Publikováno v:
Global Translational Medicine. 2:229
Cardiometabolic diseases (CMDs), which cause 31% of all global deaths, are one of the greatest public health challenges. Mineralocorticoid receptor (MR), as a key nuclear transcription factor, is an important drug target for the treatment of CMDs. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::772b3a6d798e694a95e1cbeaec194a88
https://doi.org/10.36922/gtm.v2i1.229
https://doi.org/10.36922/gtm.v2i1.229
NCOR1 maintains the homeostasis of vascular smooth muscle cells and protects against aortic aneurysm
Autor:
Lin-Juan Du, Jian-Yong Sun, Wu-Chang Zhang, Yuan Liu, Yan Liu, Wen-Zhen Lin, Ting Liu, Hong Zhu, Yong-Li Wang, Shuai Shao, Lu-Jun Zhou, Bo-Yan Chen, Hongjian Lu, Ruo-Gu Li, Feng Jia, Sheng-Zhong Duan
Publikováno v:
Cell death and differentiation.
Phenotypic modulation of vascular smooth muscle cells (VSMCs) plays critical roles in the pathogenesis of aortic aneurysm (AA). The function of nuclear receptor corepressor1 (NCOR1) in regulation of VSMC phenotype and AA is unclear. Herein, using smo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2289e365e64a4237a1abcbf40d2bb32a
https://pubmed.ncbi.nlm.nih.gov/36151473
https://pubmed.ncbi.nlm.nih.gov/36151473