Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jian-tao SHI"'
Publikováno v:
网络与信息安全学报, Vol 1, Pp 50-57 (2015)
Given its high utility value,mobile social network services(MSNS),however,has raised serious concerns about users’ location privacy.The location privacy requirements of users in MSNS are personal and dynamic,thus a metric called confidence was prop
Externí odkaz:
https://doaj.org/article/e45f778f633948d6950399bb255de507
Autor:
Xing-Rong Wang, Shuai Wang, Hong-Xia Mu, Kai-Yan Xu, Xue-Ting Wang, Jian-Tao Shi, Qi-Hang Cui, Li-Wen Zhang, Shi-Wu Chen
Publikováno v:
European journal of medicinal chemistry. 244
VEGFR-2 is an attractive therapeutic target for antitumor drug research by blocking tumor angiogenesis and PROTAC provides a new technology for targeted protein knockout. Herein, a library of novel VEGFR-2-PROTAC degraders were rationally designed an
Publikováno v:
Molecular Crystals and Liquid Crystals. 692:53-61
The title compound 2-[2-(2-fluorobenzylidene)hydrazinyl]-4-(1-methyl-1H-indol-3-yl) thieno[3,2-d]pyrimidine (C22H16FN5S) was prepared and its structure was confirmed by IR, 1H NMR, MS, elem...
Autor:
Shuai Wang, Jian-Tao Shi, Xing-Rong Wang, Hong-Xia Mu, Xue-Ting Wang, Kai-Yan Xu, Qing-Shan Wang, Shi-Wu Chen
Publikováno v:
Bioorganic Chemistry. 133:106412
Autor:
Kai-Yan, Xu, Xue-Ting, Wang, Lei, Cheng, Qi-Hang, Cui, Jian-Tao, Shi, Li-Wen, Zhang, Shi-Wu, Chen
Publikováno v:
Bioorganic & Medicinal Chemistry. 78:117152
The bromodomain-containing protein 4 (BRD4) has gained growing interest as an effective drug target for the treatment of hepatocellular carcinoma (HCC). Herein, we designed and synthesized a series of quinoxalinone derivatives as BRD4 inhibitors via
Autor:
Qi-Hang, Cui, Wen-Bo, Li, Zhao-Yang, Wang, Kai-Yan, Xu, Shuai, Wang, Jian-Tao, Shi, Li-Wen, Zhang, Shi-Wu, Chen
Publikováno v:
Bioorganic Chemistry. 128:106117
The bromodomain and extra-terminal (BET) bromodomains, particularly BRD4, have been identified as promising therapeutic targets in the treatment of many human disorders such as cancer. Coumarin is a highly privileged moiety for the development of nov
Autor:
Ju Liu1, Jian-tao Shi1, Xue-chen Hao1, Yu-tong Liu1, Shi Ding1, Yang Wang1, Ye Chen1 sy-chenye@163.com
Publikováno v:
Journal of Chemical Research. Sep2018, Vol. 42 Issue 9, p486-489. 4p.
Autor:
Ju liu Ju liu, Jun Li Jun Li, Jian tao Shi Jian tao Shi, Jie Li Jie Li, Xue chen Hao Xue chen Hao, Duang zheng Song Duang zheng Song, Yang Wang Yang Wang, Shi Ding and Ye Chen Shi Ding and Ye Chen
Publikováno v:
Journal of the chemical society of pakistan. 42:564-564
A series of novel 4-phenylaminobenzofuro[2,3-d]pyrimidine derivatives had been prepared and assessed for their in vitro antiproliferative activities against three lung cancer cell lines (A549, H460 and H1975). The bioassay results showed most of the
Autor:
Ye Chen Shi Ding, Li Jie, Jian tao Shi Jian tao Shi, Ju Liu, Li Jun, Xue chen Hao Xue chen Hao, Ye Chen, Duang zheng Song Duang zheng Song, Ding Shi, Yang Wang
Publikováno v:
Journal of the chemical society of pakistan. 42:564-564
A series of novel 4-phenylaminobenzofuro[2,3-d]pyrimidine derivatives had been prepared and assessed for their in vitro antiproliferative activities against three lung cancer cell lines (A549, H460 and H1975). The bioassay results showed most of the
Publikováno v:
International Journal of Biological Sciences
The homeobox transcription factor orthodenticle homolog 2 (otx2) is supposed as an organizer that orchestrates a transcription factor network during photoreceptor development. However, its regulation in the process remains unclear. In this study, we