Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Jian-hong Shi"'
Autor:
Na Zheng, Yihao Long, Zixuan Bai, Jianing Li, Hongyu Wang, Dan-Dan Song, Hong-Lin Liu, Jian-Hong Shi, Shuli Zhao
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background Chimeric antigen receptor CAR-T cell therapies have ushered in a new era of treatment for specific blood cancers, offering unparalleled efficacy in cases of treatment resistance or relapse. However, the emergence of cytokine relea
Externí odkaz:
https://doaj.org/article/45ee568115be4b51a9edc9b64b7df583
Autor:
Jie Wan, Cheng Cheng, Jiajia Hu, Haiyan Huang, Qiaoqiao Han, Zuliang Jie, Qiang Zou, Jian-Hong Shi, Xiaoyan Yu
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113518- (2023)
Summary: The dysfunction and clonal constriction of tumor-infiltrating CD8+ T cells are accompanied by alterations in cellular metabolism; however, how the cell-intrinsic metabolic pathway specifies intratumoral CD8+ T cell features remains elusive.
Externí odkaz:
https://doaj.org/article/ead2c7c49d40431b892e1bf1ce25de0e
Autor:
Jian-Hong Shi, Chen Ling, Ting-Ting Wang, Li-Nuo Zhang, Wen-Wen Liu, Yan Qin, Ying-Hui Tan, Nai-Peng Cui, Zhi-Yu Ni
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract TRK-fused gene (TFG) is known to be involved in protein secretion and plays essential roles in an antiviral innate immune response. However, its function in LPS-induced inflammation and pyroptotic cell death is still unknown. Here, we report
Externí odkaz:
https://doaj.org/article/91f0d54125be4b5da070330d0c8fd6dd
Autor:
Liang Ding, Yalei Wen, Xin Zhang, Fang Zhao, Kenao Lv, Jian-hong Shi, Shigang Shen, Xuefeng Pan
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract CREB-binding protein (CBP) is an acetyltransferase known to play multiple roles in the transcriptions of genes involving oxidative metabolism, cell cycle, DNA damage checkpoints, and cell death. In this study, CBP was found to positively reg
Externí odkaz:
https://doaj.org/article/43ab395dabed4a81b0f4c80d8674d4f3
Autor:
Yan Qin, Bin Zheng, Gao-shan Yang, Hao-jie Yang, Jing Zhou, Zhan Yang, Xin-hua Zhang, Hong-ye Zhao, Jian-hong Shi, Jin-kun Wen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 492-511 (2020)
Autophagy is associated with the cytoprotection of physiological processes against inflammation and oxidative stress. Salvia miltiorrhiza possesses cardiovascular protective actions and has powerful anti-oxidative and anti-inflammatory effects; howev
Externí odkaz:
https://doaj.org/article/6b3c5952ca634d3fb25f4f64088222bf
Autor:
Nai-Peng Cui, Shu Qiao, Shan Jiang, Jin-Lin Hu, Ting-Ting Wang, Wen-Wen Liu, Yan Qin, Ya-Nan Wang, Li-Shuang Zheng, Jin-Chao Zhang, Yong-Ping Ma, Bao-Ping Chen, Jian-Hong Shi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeTriple-negative breast cancer (TNBC), the most aggressive subtype of breast cancer, is associated with high invasiveness, high metastatic occurrence and poor prognosis. Protein tyrosine kinase 7 (PTK7) plays an important role in multiple cance
Externí odkaz:
https://doaj.org/article/9581539790fd4aa0b1ed381012234df9
Autor:
Dan-dan Lin, Yang Shen, Shu Qiao, Wen-wen Liu, Lishuang Zheng, Ya-nan Wang, Naipeng Cui, Yun-fan Wang, Shuli Zhao, Jian-hong Shi
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
OTUD7B, a multifunctional deubiquitinylase, plays an essential role in inflammation and proliferation signals. However, its function in lung cancer remains largely unknown. The aim of this study was to evaluate the prognostic significance of OTUD7B i
Externí odkaz:
https://doaj.org/article/cd1a1d4d21db43eeb5f436b9f55ba566
Autor:
Jian-Hong Shi, Shao-Cong Sun
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Tumor necrosis factor receptor (TNFR)-associated factors (TRAFs) are a family of structurally related proteins that transduces signals from members of TNFR superfamily and various other immune receptors. Major downstream signaling events mediated by
Externí odkaz:
https://doaj.org/article/41c39f5154cc463ba5e1205aa0e98953
Autor:
Bing Wang, Ming-zhi Zhao, Nai-peng Cui, Dan-dan Lin, An-yi Zhang, Yan Qin, Cai-yun Liu, Wei-tao Yan, Jian-hong Shi, Bao-ping Chen
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 147-154 (2015)
Krüppel‐like factor 4 (KLF4) functions as either a tumor suppressor or an oncogene in different tissues by regulating the expression of various genes. The aim of this study was to reveal the functions of KLF4 in regulating breast cancer apoptosis,
Externí odkaz:
https://doaj.org/article/60c95fe3475b4370ab0a0b5e60690e63
Autor:
Xiang-qun, Fu, Wan-su, Bao, He-liang, Huang, Tan, Li, Jian-hong, Shi, Xiang, Wang, Shuo, Zhang, Feng-guang, Li
To overcome the difficulty of realizing large-scale quantum Fourier transform (QFT) within existing technology, this paper presents a resource-saving method, namely t-bit semiclassical QFT over (Z_(2^n)), which could realize large-scale QFT using arb
Externí odkaz:
http://arxiv.org/abs/1712.08424