Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jian-guang Lu"'
Publikováno v:
Pharmaceutical Fronts, Vol 04, Iss 04, Pp e267-e274 (2022)
Saxagliptin is a therapeutic drug for diabetes. The key synthesis process of the drug involves catalyzing 2-(3-hydroxy-1-adamantyl)-2-oxoacetic acid (A) into (S)-3-hydroxyadamantane glycine (B), during which enzymes phenylalanine dehydrogenase mutant
Externí odkaz:
https://doaj.org/article/53ac3b317b504011897372c59bd0c6ae
Publikováno v:
Pharmaceutical Fronts, Vol 03, Iss 01, Pp e23-e29 (2021)
Abstract Parathyroid hormone (PTH)1–34 is an effective peptide drug for osteoporosis therapy. However, the half-life of PTH1–34 in vivo is short, leading to the need for frequent injections of this drug during its treatment. To prolong the half-l
Externí odkaz:
https://doaj.org/article/1355a70fbb414001a4dfeda5a840f6ae
Publikováno v:
Pharmaceutical Fronts, Vol 02, Iss 04, Pp e160-e167 (2020)
Adalimumab, a full-length monoclonal antibody, is widely used as an anti-tumor necrosis factor-α (anti-TNF-α) agent. In this article, we aimed to prolong the in vivo half-life of adalimumab antigen-binding fragment (Fab) through Sortase A (SrtA)-me
Externí odkaz:
https://doaj.org/article/5383e01842be40e1b986e7b6273dd37b
Publikováno v:
International Journal of Minerals, Metallurgy and Materials. 28:629-636
The effects of SiO2 content on the preparation process and metallurgical properties of acid oxidized pellets, including compressive strength, reduction, and softening—melting behaviors, were systematically investigated. Mineralogical structures, el
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e22186- (2023)
Distiller's grains, byproducts of the brewing process, represent a valuable resource for extracting natural phenolic compounds due to their significant global production. This study presents the first evidence of the protective effects of Moutai dist
Externí odkaz:
https://doaj.org/article/5cbe8c0918a74532934b0c1f8dc4af6e
Autor:
Ming Hua Li, Yu Wang, Jian-Guang Lu, De-jun Jin, Qiuying Li, Xuan Kan, Yan-Dong Zhou, Ying Liu, Yu-Li Xiao
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 16:2659-2664
Background: To examine the expression of cysteine-rich 61 (Cyr61/CCN1) protein in laryngeal squamous- cell carcinoma (LSCC) tissues, and its relationship with the tumor epithelial-mesenchymal transition (EMT), invasion, metastasis, and prognosis. Mat
Publikováno v:
European Archives of Oto-Rhino-Laryngology. 271:2233-2240
Cilengitide is a chemical synthesis cyclopeptide containing RGD sequence, which can be used as a small molecule antagonist targeted to integrin αν (ITGAV). The aim of present study was to investigate the effect on proliferation and cell apoptosis o
Publikováno v:
Pathology - Research and Practice. 209:105-109
In the past several years, the αv integrin subfamily has been repeatedly found to be involved in tumor progression and angiogenesis. The aim of this study was to investigate the expression of the integrin αv subfamily in laryngeal squamous cell car
Autor:
Wen-Na Zhang, Yuan-Yuan Li, Jia-Jia Xu, Lu-Lu Shi, Lei Chen, Yong-Ming Lu, Qing-Xi Wu, Jian-Guang Luo, Yan Chen
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105301- (2022)
Armillariella tabescens is a traditional Chinese medicinal and edible fungus which holds importance for treatment of gastrointestinal disorders. This study was aimed to evaluate the effect of methanol extract of A. tabescens (AME) in dextran sulfate
Externí odkaz:
https://doaj.org/article/c94c5d538cfb4685b7c9e4269172c9d4
Publikováno v:
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 48(6)
To compare the functional results of transoral CO2 laser epiglottectomy with transcervical supraglottic laryngectomy and to find the landmarks for CO2 laser surgery.Forty-nine preoperatively untreated patients diagnosed as clinical T1-2N0M0 epiglotti