Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Jian-gang Shen"'
Autor:
Lin-Yan Huang, Yi-De Zhang, Jie Chen, Hai-Di Fan, Wan Wang, Bin Wang, Ju-Yun Ma, Peng-Peng Li, Hai-Wei Pu, Xin-Yian Guo, Jian-Gang Shen, Su-Hua Qi
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 845-857 (2025)
It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late stroke. Indeed, previous studies have shown that excessive increases in hypochlorous acid after stro
Externí odkaz:
https://doaj.org/article/08ee337d90284669a878ac0b5ed188cd
Autor:
Lin-Yan Huang, Ju-Yun Ma, Jin-Xiu Song, Jing-Jing Xu, Rui Hong, Hai-Di Fan, Heng Cai, Wan Wang, Yan-Ling Wang, Zhao-Li Hu, Jian-Gang Shen, Su-Hua Qi
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 1040-1045 (2023)
Ischemic accumulation of succinate causes cerebral damage by excess production of reactive oxygen species. However, it is unknown whether ischemic accumulation of succinate affects neural stem cell proliferation. In this study, we established a rat m
Externí odkaz:
https://doaj.org/article/9ce18f7cfdfd4f94a2cd6714e11893a7
Autor:
Heng Cai, Lin-Yan Huang, Rui Hong, Jin-Xiu Song, Xin-Jian Guo, Wei Zhou, Zhao-Li Hu, Wan Wang, Yan-Ling Wang, Jian-Gang Shen, Su-Hua Qi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the present study, we isolated and characterized novel ELNs from Momordic
Externí odkaz:
https://doaj.org/article/43ba6dc420ac4b5d982e974d610cbb93
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 5, Iss 2, Pp 104-115 (2019)
Neural stem/progenitor cells (NSCs) could be attractive therapeutic targets for promoting adult neurogenesis, brain plasticity, and repair in stroke and neurodegenerative diseases, raising great potentials for regeneration therapy. In adult ischemic
Externí odkaz:
https://doaj.org/article/0c863d286f8047dd8ee3a156a11ec77c
Autor:
Jian-Gang SHEN
Publikováno v:
Digital Chinese Medicine, Vol 1, Iss 3, Pp 191-197 (2018)
ABSTRACT: Stroke is the leading cause of human disability with limited effective drugs availability. The disruption of multiple signaling pathways in stroke makes developing new drugs be difficult. Traditional Chinese medicine (TCM) has its unique ad
Externí odkaz:
https://doaj.org/article/1a43ddc8b1a14bef9f3d34f45b7daaef
Autor:
Su-Hua Qi, Lin-Yan Huang, Ju-Yun Ma, Jin-Xiu Song, Jing-Jing Xu, Rui Hong, Hai-Di Fan, Heng Cai, Wan Wang, Yan-Ling Wang, Zhao-Li Hu, Jian-Gang Shen
Publikováno v:
Neural regeneration research. 18(5)
Ischemic accumulation of succinate causes cerebral damage by excess production of reactive oxygen species. However, it is unknown whether ischemic accumulation of succinate affects neural stem cell proliferation. In this study, we established a rat m
Autor:
Lap Ki Chan, Nai Sum Wong, Gordon Tin Chun Wong, Jody K. P. Chu, Arkers Kwan Ching Wong, Lei King Yu, Susan Bridges, Julie Y. Chen, Veronica Suk fun Lam, Tin Pui Yum, Chak Sing Lau, Jian Gang Shen, Tai Pong Lam, Janet Yuen Ha Wong, Qingyun Li, Winnie W.Y. Tso, Fraide A. Ganotice, Hai-Yong Chen, Charlene C. Ho, Jacqueline Mei Chi Ho, Phoebe Wing Lam Chan, Frances Kam Yuet Wong, Namkiu Chan, Julian A. Tanner, Alan J. Worsley, Celia Hoi Yan Chan
Publikováno v:
BMC Medical Education, Vol 17, Iss 1, Pp 1-12 (2017)
BMC Medical Education
BMC Medical Education
Background Interprofessional learning is gaining momentum in revolutionizing healthcare education. During the academic year 2015/16, seven undergraduate-entry health and social care programs from two universities in Hong Kong took part in an interpro
Publikováno v:
The Journal of Immunology. 196:119.18-119.18
Multiple Sclerosis (MS) is a progressive autoimmune disease in central nervous system (CNS) with its pathogenesis not fully understood. In the present study, we demonstrated that caveolin-1, a major membrane scaffolding protein, plays a critical role
Autor:
Dan, Yang, Zhen-Ning, Sun, Tao, Peng, Hua-Li, Wang, Jian-Gang, Shen, Yan, Chen, Paul Kwong-Hang, Tam
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 591
Peroxynitrite (ONOO(-)) and hypochlorous acid (HOCl) are two highly reactive oxygen species generated in biological systems. The overproduction of peroxynitrite or hypochlorous acid is implicated in a broad array of human pathologies including vascul
Publikováno v:
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. 16(11)
To investigate the effects of FAK-related non-kinase (FRNK) on the apoptosis of hepatic stellate cells (HSC) in vitro and on the extracellular signal-regulated kinase (ERK) signal transduction pathway.HSC were stimulated by fibronectin (FN), and then