Výsledky vyhledávání - "Jian-fang Feng"

Akademický článek

Pharmacokinetics of five phthalides in volatile oil of Ligusticum sinense Oliv.cv. Chaxiong, and comparison study on physicochemistry and pharmacokinetics after being formulated into solid dispersion and inclusion compound

Autor: Peng-yi Hu, Ying-huai Zhong, Jian-fang Feng, Dong-xun Li, Ping Deng, Wen-liu Zhang, Zhi-qiang Lei, Xue-mei Liu, Guo-song Zhang

Publikováno v: BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-16 (2021)

Abstract Backgrounds The dried rhizome of Ligusticum sinense Oliv.cv. Chaxiong has been used to treat cardiovascular and cerebrovascular diseases, atherosclerosis, anemia and stroke. A high purity extract from chaxiong (VOC, brownish yellow oil) was

Externí odkaz: https://doaj.org/article/3c1d250176a04f23935db848908e6ce6

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Preparation, in vitro and in vivo Evaluation of Thermosensitive in situ Gel Loaded with Ibuprofen-Solid Lipid Nanoparticles for Rectal Delivery

Autor: Chun-hui Huang, Peng-yi Hu, Qiu-yan Wu, Ming-yan Xia, Wen-liu Zhang, Zhi-qiang Lei, Dong-Xun Li, Guo-song Zhang, Jian-fang Feng

Publikováno v: Drug Design, Development and Therapy. 16:1407-1431

Chun-hui Huang,1,2,* Peng-yi Hu,2,3,* Qiu-yan Wu,2,3 Ming-yan Xia,2,3 Wen-liu Zhang,3 Zhi-qiang Lei,3 Dong-xun Li,3 Guo-song Zhang,2,3 Jian-fang Feng1,2 1School of Pharmacy, Guangxi University of Chinese Medicine, Nanning, Guangxi, 530200, Pe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598e08542da9f30bb7ee5c783f0f06c9
https://doi.org/10.2147/dddt.s350886

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[Research progress on liposome and nanomicelle targeted drug delivery system across blood-brain barrier]

Autor: Xu, Yang, Ling-Hui, Zou, Wen-Ya, Ding, Zhong-Bin, Zhang, Jin-Qing, Chen, Ji-Lang, Li, Hong-Li, Feng, Yu-Yang, Li, Ling, Tang, Jian-Fang, Feng

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 47(22)

The blood-brain barrier(BBB), a protective barrier between brain tissues and brain capillaries, can prevent drugs from entering the brain tissues to exert the effect, which greatly increases the difficulty in treating brain diseases. The drug deliver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c9c95c83f293aad77a827a1915dc7c67
https://pubmed.ncbi.nlm.nih.gov/36471922

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Autor: Zhang Guosong, Jian-fang Feng, Zhang Wenliu, Dong-xun Li, Lei Zhiqiang, Ying-huai Zhong, Xue-mei Liu, Ping Deng, Hu Pengyi

Publikováno v: BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-16 (2021)

Backgrounds The dried rhizome of Ligusticum sinense Oliv.cv. Chaxiong has been used to treat cardiovascular and cerebrovascular diseases, atherosclerosis, anemia and stroke. A high purity extract from chaxiong (VOC, brownish yellow oil) was extracted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105a0df096beb0a5d938a755323b2ca3
https://doi.org/10.1186/s12906-021-03289-z

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[Pharmacokinetic study on five components in phthalide target areas of Chaxiong and its β-CD inclusion compounds based on UPLC-MS/MS]

Autor: Ying-Huai, Zhong, Jian-Fang, Feng, Ming-Yan, Xia, Xin-Hua, Wei, Qiu-Yan, Wu, Dong-Xun, Li, Xue-Mei, Liu, Guo-Song, Zhang

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 46(4)

This study aims to establish a method for the determination of the concentration of five main components of phthalide target areas of Chaxiong(CPTA) and its inclusion of β-CD in the plasma of rats, and determine the pharmacokinetic parameters, absol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8b280e6ff1d771164ff071d20ede138
https://pubmed.ncbi.nlm.nih.gov/33645104

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[Effect and mechanism of total flavonoids of Lichi Semen on CCl_4-induced liver fibrosis in rats, and prediction of Q-marker]

Autor: Yin-Yi, Feng, Jiong-Yi, Yan, Xing, Xia, Jian-Qin, Liang, Fang, Li, Tan-Fang, Xie, Wei-Sheng, Luo, Jian-Fang, Feng

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 45(23)

This paper was to investigate the effect of total flavonoids of Lichi Semen(TFL) on carbon tetrachloride(CCl_4)-induced liver fibrosis in rats, analyze and predict its mechanism of action and potential quality markers(Q-marker). Firstly, male SD rats

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7340439a3d5b738c4bb022adcbe3c85
https://pubmed.ncbi.nlm.nih.gov/33496112

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[Development and characterization of TPGS modified proniosomes of docetaxel]

Autor: He-long, Liu, Kai-li, Hu, Jian-fang, Feng

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 40(19)

A novel oral delivery system that TPGS modified docetaxel proniosomes, DTX-TPGS-PN, was developed and the characterization after hydration was observed. Firstly, Doce-TPGS-PN was optimized by investing the factors, including the type of surfactant, m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a5699e9fef54c3fb9547b843ac0dbb7f
https://pubmed.ncbi.nlm.nih.gov/26975101

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[Progress in regulation effect of aromatic refreshing traditional Chinese medicine on BBB permeability and its mechanism]

Autor: Li-Ping, Wang, Jian-Fang, Feng, Kai-Li, Hu

Publikováno v: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 39(6)

The blood-brain barrier (BBB) protects the brain against unwanted substances, while, at the same time, limits the transport of many drugs into the brain. Aromatic refreshing traditional Chinese medicine (TCM) can induce resuscitation and modify the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c8e4c78fe926c3ce126d35d0f162778d
https://pubmed.ncbi.nlm.nih.gov/24956831

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Cardiac Specific Overexpression of Transglutaminase II (Gh) Results in a Unique Hypertrophy Phenotype Independent of Phospholipase C Activation

Autor: Gerald W. Dorn, John N. Lorenz, Elizabeth T. Donnelly, Kersten M. Small, Jian-Fang Feng, Mie-Jae Im, Andrew Yu, Stephen B. Liggett

Publikováno v: Journal of Biological Chemistry. 274:21291-21296

Tissue type transglutaminase (TGII, also known as G(h)) has been considered a multifunctional protein, with both transglutaminase and GTPase activity. The role of the latter function, which is proposed as a coupling mechanism between alpha(1)-adrener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9555590aae73e44c21e09c2072631422
https://doi.org/10.1074/jbc.274.30.21291

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α1B-Adrenoceptor Interacts with Multiple Sites of Transglutaminase II: Characteristics of the Interaction in Binding and Activation

Autor: Caroline D. Gray, Jian-Fang Feng, Mie-Jae Im

Publikováno v: Biochemistry. 38:2224-2232

We previously reported that a novel GTP binding protein (G alpha h) is tissue type transglutaminase (TGII) and transmits the alpha 1B-adrenoceptor (AR) signal to phospholipase C (PLC) through its GTPase function. We have also shown that PLC-delta 1 i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366704bc8e03803166372126292cfefa
https://doi.org/10.1021/bi9823176

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