Zobrazeno 1 - 10
of 302
pro vyhledávání: '"Jian-bo Wan"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 4045-4058 (2024)
Although serving as the workhorse, MS/MS cannot fully satisfy the analytical requirements of quantitative sub-metabolome characterization. Because more information intrinsically correlates to more structural and concentration clues, here, efforts wer
Externí odkaz:
https://doaj.org/article/c6d508e887d941d88e50cc67ef1cb869
Publikováno v:
Journal of Advanced Research, Vol 63, Iss , Pp 255-267 (2024)
Introduction: Methicillin-resistant Staphylococcus aureus (MRSA)-caused infections greatly threaten public health. The discovery of natural-product-based anti-MRSA agents for treating infectious diseases has become one of the current research focuses
Externí odkaz:
https://doaj.org/article/113302980cda4d968c2782fdbbadd75e
Autor:
Yingzhi Chen, Ruike Li, Qiao Duan, Lingling Wu, Xinyi Li, Aoxiang Luo, Yongming Zhang, Na Zhao, Kai Cui, Wenwei Wu, Tize Liu, Jian‐Bo Wan, Liufu Deng, Guiying Li, Lijun Hou, Weihong Tan, Zeyu Xiao
Publikováno v:
Advanced Science, Vol 11, Iss 32, Pp n/a-n/a (2024)
Abstract The activation of cyclic GMP‐AMP (cGAMP) synthase (cGAS) and its adaptor, stimulator of interferon genes (STING), is known to reprogram the immunosuppressive tumor microenvironment for promoting antitumor immunity. To enhance the efficienc
Externí odkaz:
https://doaj.org/article/3a4fa06c0ca94787bb78c4697c2a55ef
Autor:
Li-Juan Ma, Xiao Liu, Liwei Guo, Yuan Luo, Beibei Zhang, Xiaoxue Cui, Kuan Yang, Jing Cai, Fang Liu, Ni Ma, Feng-Qing Yang, Xiahong He, She-Po Shi, Jian-Bo Wan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Plants usually produce defence metabolites in non-active forms to minimize the risk of harm to themselves and spatiotemporally activate these defence metabolites upon pathogen attack. This so-called two-component system plays a decisive role
Externí odkaz:
https://doaj.org/article/2b6929564ed545fb9673931fc6f7299c
Autor:
Pengde Lu, Jinfen Chen, Ying Chen, Xingping Quan, Jiayue Liu, Yan Han, Yiyang Li, Li Yang, Jian‐Bo Wan, Yonghua Zhao
Publikováno v:
Food Frontiers, Vol 4, Iss 4, Pp 2081-2096 (2023)
Abstract Ulcerative colitis (UC) is a digestive disease with a high incidence and is difficult to be cured due to its complex etiology. It has evidenced that intestinal barrier dysfunction plays a predominant role in UC. 20(S)‐protopanaxadiol sapon
Externí odkaz:
https://doaj.org/article/1b8b6d241af54306b270ebe9464dae90
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 10, Pp 1221-1231 (2023)
Fatty acids (FAs), which were initially recognized as energy sources and essential building blocks of biomembranes, serve as the precursors of important signaling molecules. Tracing FA metabolism is essential to understanding the biochemical activity
Externí odkaz:
https://doaj.org/article/b521d495df194b17b60483075b20c40e
Publikováno v:
Small Structures, Vol 4, Iss 2, Pp n/a-n/a (2023)
Luminescence bioimaging and biosensing in the second near‐infrared (NIR‐II) spectral window (1,000–1,700 nm wavelengths) is a newly emerging technique that is extensively used in fundamental research and clinical practice. Owing to its advantag
Externí odkaz:
https://doaj.org/article/4d56fc0a7a364d668c2c1ee819919005
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-15 (2022)
Abstract Background Red yeast rice (RYR), a nutraceutical with a profound cholesterol-lowering effect, was found to attenuate non-alcoholic fatty liver disease (NAFLD) in mice. Despite monacolin K in RYR being a specific inhibitor of hydroxymethylglu
Externí odkaz:
https://doaj.org/article/43942f86a3d94baca03ed89ceaa8e5a8
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-12 (2021)
Abstract Background The Chinese medicinal wine made from herbal medicines became prevalent among Chinese people. The Chinese herbal spirit is composed of several herbal extracts, and has the certain health functions, such as anti-fatigue and immune r
Externí odkaz:
https://doaj.org/article/9439201298ce4740b9b2affc0448f0b8
Autor:
Yi-Yao Yang, Zhao-Yu Wu, Fang-Bo Xia, Hao Zhang, Xu Wang, Jian-Li Gao, Feng-Qing Yang, Jian-Bo Wan
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-14 (2020)
Abstract Background The dry root and rhizome of Ligusticum chuanxiong Hort., or Chuanxiong, has been used as a blood-activating and stasis-removing traditional Chinese medicine for 1000 years. Our previous studies have shown the inhibitory activity o
Externí odkaz:
https://doaj.org/article/f360b28767094f39b3d5948099338110