Výsledky vyhledávání - "Jian-Zhong Xiang"

Effects of inorganic phosphate and ADP on calcium handling by the sarcoplasmic reticulum in rat skinned cardiac muscles

Autor: Jian-Zhong Xiang, Jonathan C. Kentish

Publikováno v: Cardiovascular Research. 29:391-400

Objective: The aim was to investigate whether, and how, increases in inorganic phosphate (Pi) and ADP, similar to those occurring intracellularly during early myocardial ischaemia, affect the calcium handling of the sarcoplasmic reticulum. Methods: R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::864cbb1bded59fc1109b043db192432c
https://doi.org/10.1016/s0008-6363(96)88597-x

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Quisqualate and carbachol-induced increases in intrasynaptosomal free calcium are mediated by different products of phospholipid hydrolysis

Autor: Iain C. Campbell, Michael Brammer, Jian-Zhong Xiang

Publikováno v: European Journal of Pharmacology: Molecular Pharmacology. 207:93-100

The mechanisms by which quisqualate and carbachol increase intrasynaptosomal free calcium ([Ca2+]i) were studied in rat cortical synaptosomes. Quisqualate (0.01-100 microM) and carbachol (100-1000 microM) increased [Ca2+]i in Fura-2 acetoxymethyl est

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea773fc9b484fe8967a428ec95575bd
https://doi.org/10.1016/0922-4106(91)90083-t

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Studies of receptor-mediated inhibition of 45Ca accumulation into synaptosomes

Autor: Iain C. Campbell, Michael Brammer, Jian-Zhong Xiang

Publikováno v: British Journal of Pharmacology. 101:140-144

1. The effects of alpha 2-adrenoceptor and kappa-opiate receptor activation on 45Ca accumulation into rat cortical synaptosomes were examined. 2. Clonidine (1 microM) and U50488H (1 microM) significantly reduced 45Ca accumulation under both resting (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984ec522757644a34eb58f55ac547fd2
https://doi.org/10.1111/j.1476-5381.1990.tb12103.x

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Regulation of Calcium Concentrations in Synaptosomes: α 2 ‐Adrenoceptors Reduce Free Ca 2+ by Closure of N‐Type Ca 2+ Channels

Autor: Michael Brammer, Iain C. Campbell, John Morton, Jian-Zhong Xiang

Publikováno v: Journal of Neurochemistry. 55:303-310

The relationship between intrasynaptosomal total (CaT) and free ([Ca2+]i) calcium and 45Ca accumulation was studied under physiological and K+-depolarised conditions in rat cortical synaptosomes. Under physiological conditions, CaT (10.7 mM) was ∼

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938be18cf5b475d80418dbc95ecadb5b
https://doi.org/10.1111/j.1471-4159.1990.tb08852.x

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Neuronal responses related to long-term recognition memory processes in prefrontal cortex

Autor: Malcolm W. Brown, Jian-Zhong Xiang

Publikováno v: Neuron. 42(5)

Much evidence indicates that prefrontal cortex plays an important role in long-term recognition memory processes. Here, we report primate prefrontal neuronal responses carrying information necessary for long-term visual recognition memory. The respon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69d45fc5668b9394b10f6634261244c
https://pubmed.ncbi.nlm.nih.gov/15182720

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Ca(2+)- and caffeine-induced Ca2+ release from the sarcoplasmic reticulum in rat skinned trabeculae: effects of pH and Pi

Autor: Jonathan C. Kentish, Jian-Zhong Xiang

Publikováno v: Cardiovascular research. 33(2)

Objective: Our aims were: (1) to examine the effect of pH (7.4–6.5) on Ca2+release from the sarcoplasmic reticulum (SR) of cardiac muscle, and (2) to see if these effects were altered by phosphate (Pi). Methods: Rat ventricular trabeculae were perm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668220026356b5e4b4e3eddff65a815a
https://pubmed.ncbi.nlm.nih.gov/9074695

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