Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jian-Ren Gu"'
Autor:
Qing Li, Xiao-Xin Zhang, Li-Peng Hu, Bo Ni, Dong-Xue Li, Xu Wang, Shu-Heng Jiang, Hui Li, Min-Wei Yang, Yong-Sheng Jiang, Chun-Jie Xu, Xue-Li Zhang, Yan-Li Zhang, Pei-Qi Huang, Qin Yang, Yang Zhou, Jian-ren Gu, Gary Gui-Shan Xiao, Yong-wei Sun, Jun Li, Zhi-Gang Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Pancreatic ductal adenocarcinoma (PDAC) cells can utilise the tumour microenvironment to metastasise to the liver. Here the authors show that hepatoctyes overexpress SLIT2 to enable premetastatic niche formation for ROBO1-positive PDAC cells to suppo
Externí odkaz:
https://doaj.org/article/c0db6eed419d4fa68ab125432f399435
Autor:
Qing Li, Chun-Chao Zhu, Bo Ni, Zi-Zhen Zhang, Shu-Heng Jiang, Li-Peng Hu, Xu Wang, Xiao-Xin Zhang, Pei-Qi Huang, Qin Yang, Jun Li, Jian-Ren Gu, Jia Xu, Kathy Qian Luo, Gang Zhao, Zhi-Gang Zhang
Publikováno v:
EBioMedicine, Vol 49, Iss , Pp 157-171 (2019)
Background: Liver is one of the most preferred destinations of distant metastasis in gastric cancer (GC). As effective treatment is still limited, the prognosis of GC patients bearing liver metastasis is poor. We filter out lysyl oxidase (LOX) to stu
Externí odkaz:
https://doaj.org/article/edcd77c5fe0c433e8e605ee185580478
Autor:
Shu-Heng Jiang, Xiao-Xin Zhang, Li-Peng Hu, Xu Wang, Qing Li, Xue-Li Zhang, Jun Li, Jian-Ren Gu, Zhi-Gang Zhang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The overarching view of current tumor therapies simplifies cancer to a cell-biology problem in which neoplasms are caused solely by malignant cells and the exploration of carcinogenesis and tumor progression largely focuses on somatic mutations and o
Externí odkaz:
https://doaj.org/article/2665905fc0f949009d7813d8dc1f676c
Autor:
Guang-Ang Tian, Chun-Jie Xu, Kai-Xia Zhou, Zhi-Gang Zhang, Jian-Ren Gu, Xue-Li Zhang, Ya-Hui Wang
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1
Externí odkaz:
https://doaj.org/article/018ed00bbf094826a0892b29d0856e6d
Autor:
Ya-Hui Wang, Rong-Kun Li, Ying Fu, Jun Li, Xiao-Mei Yang, Yan-Li Zhang, Lei Zhu, Qin Yang, Jian-Ren Gu, Xin Xing, Zhi-Gang Zhang
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Exemestane (EXE) is an irreversible steroidal aromatase inhibitor mainly used as an adjuvant endocrine therapy for postmenopausal women suffering from breast cancer. Besides inhibiting aromatase activity, EXE has multiple biological functions, such a
Externí odkaz:
https://doaj.org/article/978766c41b2a4c84ae660cad480d0032
Autor:
Qing Li, Xiao-Xin Zhang, Li-Peng Hu, Bo Ni, Xu Wang, ShuHeng Jiang, Min-Wei Yang, Yong-shen Jiang, Chun-Jie Xu, Xueli Zhang, Yanli Zhang, Pei-Qi Huang, Qin Yang, Yang Zhou, Jian-ren Gu, Gary Gui-Shan Xiao, Yong-Wei Sun, Jun Li, Zhi-Gang Zhang
To explore the mechanism of co-evolution and potential driver of which in pancreatic ductal adenocarcinoma (PDAC) metastasis to liver, we studied key molecules involved in this progress and their translational values. Pre-metastatic niche (PMN) and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03dcf0e0f12d4011660225f0d2f82d1c
https://doi.org/10.21203/rs.3.rs-76006/v1
https://doi.org/10.21203/rs.3.rs-76006/v1
Autor:
Shu-Heng, Jiang, Li-Li, Zhu, Man, Zhang, Rong-Kun, Li, Qin, Yang, Jiang-Yu, Yan, Ce, Zhang, Jian-Yu, Yang, Fang-Yuan, Dong, Miao, Dai, Li-Peng, Hu, Jun, Li, Qing, Li, Ya-Hui, Wang, Xiao-Mei, Yang, Yan-Li, Zhang, Hui-Zhen, Nie, Lei, Zhu, Xue-Li, Zhang, Guang-Ang, Tian, Xiao-Xin, Zhang, Xiao-Yan, Cao, Ling-Ye, Tao, Shan, Huang, Yong-Sheng, Jiang, Rong, Hua, Kathy, Qian Luo, Jian-Ren, Gu, Yong-Wei, Sun, Shangwei, Hou, Zhi-Gang, Zhang
Publikováno v:
Gut. 68(11)
Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer-related death worldwide. Neurotransmitter-initiated signalling pathway is profoundly implicated in tumour initiation and progression. Here, we investigated whether dysregulated neur
Autor:
Xiao-Xin Zhang, Jiao Li, Jian-Yu Yang, Jie Hong, Min-Wei Yang, De-Jun Liu, Xiao-Mei Yang, Miao Dai, Jun Li, Yong-Wei Sun, Qing Li, Shan-Yun Wen, Shu-Heng Jiang, Ping He, Ya-Hui Wang, Mingxuan Feng, Jian-Ren Gu, Rong Hua, Guang-Ang Tian, Xue-Liang Fu, Xiao-Yan Cao, Zhigang Zhang, Yang Wang, Yan-Miao Huo
Publikováno v:
Oncotarget
// Shu-Heng Jiang 1, 2, * , Yang Wang 1, 2, 4, * , Jian-Yu Yang 3, * , Jun Li 2, * , Ming-Xuan Feng 5 , Ya-Hui Wang 1, 2 , Xiao-Mei Yang 2 , Ping He 2 , Guang-Ang Tian 2 , Xiao-Xin Zhang 2 , Qing Li 1, 2 , Xiao-Yan Cao 2 , Yan-Miao Huo 3 , Min-Wei Ya
Publikováno v:
Macromolecular Chemistry and Physics. 207:1359-1367
Linear, three- and four-armed block copolymers based on PEG and PSA were synthesized by melt polycondensation reactions. The CMC of the copolymer was measured using the dye solubilization method. The copolymers were found to self-aggregate in water t