Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Jian-Qin Jiang"'
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Akademický článek
Total Flavonoids of Glycyrrhiza uralensis Alleviates Irinotecan-Induced Colitis via Modification of Gut Microbiota and Fecal Metabolism
Autor: Shi-Jun Yue, Yi-Feng Qin, An Kang, Hui-Juan Tao, Gui-Sheng Zhou, Yan-Yan Chen, Jian-Qin Jiang, Yu-Ping Tang, Jin-Ao Duan
Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Irinotecan (CPT-11)-induced gastrointestinal toxicity strongly limits its anticancer efficacy. Glycyrrhiza uralensis Fisch., especially flavonoids, has strong anti-inflammatory and immunomodulatory activities. Herein, we investigate the protective ef
Externí odkaz: https://doaj.org/article/c9388c9bbebc4d0eb0950143a50ff0cd
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2
Comparative chemical profiling of three TCM drugs in the Paeoniaceae family by UPLC-MS/MS combined with chemometric methods
Autor: Jian-Qin Jiang, Hu Qinmei, Yuntian Zhang, Lu Meng, Yuqi Zhou, Yanjuan Zhai
Publikováno v: Biochemical Systematics and Ecology. 83:121-129
Paeoniae Radix Rubra (Chi-Shao in Chinese) and Paeoniae Radix Alba (Bai-Shao in Chinese) are two valuable traditional Chinese medicine (TCM) drugs, usually indicated for menstrual disorders and viral infections. Paeonia anomala subsp. anomala (Xinjia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94100846b67de9b2b8de34eff8226a42
https://doi.org/10.1016/j.bse.2019.02.002
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3
Novel berberine derivatives: Design, synthesis, antimicrobial effects, and molecular docking studies
Autor: Ling Yao, Kang Liu, Jian-Qin Jiang, Shu-Yuan Zhang, Qian Li, Ling-Ling Wu, Qin-Mei Hu
Publikováno v: Chinese Journal of Natural Medicines. 16:774-781
A series of berberine derivatives were synthesized by introducing substituted benzyl groups at C-9. All these synthesized compounds (4a-4m) were screened for their in vitro antibacterial activity against four Gram-positive bacteria and four Gram-nega
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fd7ed410d2271e6385e23bdb873633
https://doi.org/10.1016/s1875-5364(18)30117-1
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Chemo Proling and Simultaneous Analysis of Different Combinations of Sinomenii Caulis and Ramulus Cinnamomi Using UHPLC-Q-TOF-MS, GC-MS and HPLC Methods
Autor: Mengqiu Xia, Liu Liu, Jian-Qin Jiang, Lu Zhang, Xiaoqin Chu, Chunling Tian, Shuangying Gui
Publikováno v: Journal of chromatographic science. 59(7)
Objective Sinomenii Caulis (QingFengTeng) and Ramulus Cinnamomi (GuiZhi) are traditional Chinese drugs that have been used for anti-inflammation. In this study, the team plans to find out the material basis of a Chinese herb combination composed of t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e80a238c44c22d86240d32ed04d04757
https://pubmed.ncbi.nlm.nih.gov/33969409
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6
The Effect of Prescription on the Framework of Lipid Matrix and In Vitro Properties
Autor: Qian Li, Yong Zhang, Xiaoqin Chu, Zhengguang Li, Jie Huang, Shuangying Gui, Jian-Qin Jiang
Publikováno v: Current drug delivery. 16(8)
Purpose: To clarify the inner framework and relative properties in vitro of Lyotropic liquid crystal (LLC) based on various prescriptions by using hydrophilic sinomenine hydrochloride (SH) and lipophilic cinnamaldehyde (CA) as model drugs. Methods: P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac7d56b9f191ed8dc139eaabafb7724
https://pubmed.ncbi.nlm.nih.gov/31250753
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Discovery and structural optimization of 4-(4-(benzyloxy)phenyl)-3,4-dihydropyrimidin-2(1H)-ones as RORc inverse agonists
Autor: Luo Xiaoyu, Yan Zhang, Chun Wu, Y. Zhou, Yong-Zhi Lu, Yong Xu, Yanli Xing, Rui Wang, Jian-Qin Jiang, Wu Xishan, Yu Song, Xiaoqian Xue
Publikováno v: Acta Pharmacologica Sinica. 37:1516-1524
Retinoic acid receptor-related orphan nuclear receptors (RORs) are orphan nuclear receptors that show constitutive activity in the absence of ligands. Among 3 subtypes of RORs, RORc is a promising therapeutic target for the treatment of Th17-mediated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71768aa19dfbcbbe17b4de7fd17db5dc
https://doi.org/10.1038/aps.2016.32
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8
On the Structure and Transdermal Profile of Liquid Crystals Based on Phytantriol
Autor: Qian Li, Xiaoqin Chu, Jian-Qin Jiang, Zhengguang Li, Shuangying Gui, Jie Huang, Jiaojiao Cao
Publikováno v: Current drug delivery. 15(10)
Background There has been a growing concern in transdermal drug technology over the past several decades. As a novel transdermal delivery system, Lyotropic liquid crystals (LLC) still face challenges such as drug loading, limited drug permeation and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683ca2e94ec91af47b8760f14db98ca0
https://pubmed.ncbi.nlm.nih.gov/30198435
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9
Characterization and In Vitro Permeation Study of Cubic Liquid Crystal Containing Sinomenine Hydrochloride
Autor: Zhengguang Li, Jiaojiao Cao, Qian Li, Xiaoqin Chu, Shuangying Gui, Jian-Qin Jiang
Publikováno v: AAPS PharmSciTech. 19(5)
This study developed a new transdermal delivery system for the improved delivery of sinomenine hydrochloride (SH). The delivery system utilized the advantages of lyotropic liquid crystals (LLC) creating an adaptable system that offers a variety of op
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae45010869036fe5e5daad770120f3f2
https://pubmed.ncbi.nlm.nih.gov/29740759
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