Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jian-Qiao Gu"'
Autor:
Paul Brian, Marie-Françoise Coëffet-Le Gal, Jian-Qiao Gu, Sascha Doekel, Min Chu, Richard H. Baltz
Publikováno v:
Microbiology. 154:2872-2880
Genetic engineering has been applied to reprogramme non-ribosomal peptide synthetases (NRPSs) to produce novel antibiotics, but little is known about what determines the efficiency of production. We explored module exchanges at nucleotide sequences e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14fe26f00de85ca63df44e44fc20171
https://doi.org/10.1099/mic.0.2008/020685-0
https://doi.org/10.1099/mic.0.2008/020685-0
Autor:
Jian-Qiao Gu, Vivian Miao, Paul Brian, Dylan C. Alexander, Kien T. Nguyen, Richard H. Baltz, Daniel Ritz, Min Chu
Publikováno v:
Proceedings of the National Academy of Sciences. 103:17462-17467
Daptomycin, a cyclic lipopeptide produced by Streptomyces roseosporus , is the active ingredient of Cubicin (daptomycin-for-injection), a first-in-class antibiotic approved for treatment of skin and skin-structure infections caused by Gram-positive p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::544d041fb792bae1d630bd0fd4bfa27a
https://doi.org/10.1073/pnas.0608589103
https://doi.org/10.1073/pnas.0608589103
Publikováno v:
Zeitschrift für Naturforschung C. 59:797-802
Antitubercular bioassay-guided fractionation of the dichloromethane extracts of the above-ground biomass and roots of Quinchamalium majus led to the identification of six known constituents, betulinic acid (1), daucosterol (2), 5,7-dihydroxyflavone (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04337b0f2dee1167f1b2ed4dfcd76e44
https://doi.org/10.1515/znc-2004-11-1206
https://doi.org/10.1515/znc-2004-11-1206
Autor:
Yuehong Wang, Danzhou Yang, Jian Qiao Gu, Gloria Montenegro, Scott G. Franzblau, Barbara N. Timmermann
Publikováno v:
Planta Medica. 70:509-514
Antitubercular bioassay-guided fractionation of the n-hexane- and CH (2)Cl (2)-soluble extracts of the above-ground biomass and roots of Valeriana laxiflora led to the isolation of a new iridolactone, (4R,5R,7S,8S,9S)-7-hydroxy-8-hydroxymethyl-4-meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388eaf5936b7aeffe0763c4ddeb5fd59
https://doi.org/10.1055/s-2004-827149
https://doi.org/10.1055/s-2004-827149
Publikováno v:
Current Organic Chemistry. 7:213-226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21470fabc8652e1bcefd7be186064161
https://doi.org/10.2174/1385272033373003
https://doi.org/10.2174/1385272033373003
Autor:
John M. Pezzuto, A. Douglas Kinghorn, Jian-Qiao Gu, Harry H. S. Fong, Eun Jung Park, Soedarsono Riswan, Stephen Totura
Publikováno v:
Journal of Natural Products. 65:1065-1068
Activity-guided fractionation of an ethyl acetate extract of the twigs of Hernandia ovigera, using a soft agar assay with JB6 murine epidermal cells, led to the isolation of two new naturally occurring aryltetralin lignans, (7R,8S,7'R,8'R)-(+)-7'-ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fff5334735a761dbd7cad06a82e7375
https://doi.org/10.1021/np020042w
https://doi.org/10.1021/np020042w
Autor:
Eun Jung Park, Michael E. Hawthorne, Rajendra G. Mehta, A. Douglas Kinghorn, Norman R. Farnsworth, Jian-Qiao Gu, Lumonadio Luyengi, John M. Pezzuto
Publikováno v:
Phytochemistry. 58:121-127
A triterpenoid, 3β- cis - p -coumaroyloxy-2α,23-dihydroxyolean-12-en-28-oic acid ( 1 ), and two natural products, 3β- trans - p -coumaroyloxy-2α,23-dihydroxyolean-12-en-28-oic acid ( 2 ) and 23- trans - p -coumaroyloxy-2α,3β-dihydroxyolean-12-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c685a85251c4605f5af3bd5fef5b6be8
https://doi.org/10.1016/s0031-9422(01)00180-7
https://doi.org/10.1016/s0031-9422(01)00180-7
Publikováno v:
Phytochemical Analysis. 7:152-155
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7bc9cadda3d90c0f3eb6ed5a9a04385
https://doi.org/10.1002/(sici)1099-1565(199605)7:3<152::aid-pca295>3.0.co
https://doi.org/10.1002/(sici)1099-1565(199605)7:3<152::aid-pca295>3.0.co
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 60:o773-o775
The structure of an iridolactone isolated from Valeriana laxiflora was established as (4R,4aR,6S,7S,7aS)-6-hydroxy-7-hydroxymethyl-4-methylperhydrocyclopenta[c]pyran-1-one chloroform solvate, C(10)H(16)O(4).CHCl(3). The two rings are cis-fused. The d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed67667f880c7fae366898966cb15004
https://doi.org/10.1107/s0108270104021511
https://doi.org/10.1107/s0108270104021511
Publikováno v:
The Journal of antibiotics. 64(1)
A potent new lipopeptide antibiotic, A54145E(Asn(3)Asp(9)), was isolated from the fermentation broth of Streptomyces fradiae DA1489 engineered to delete genes encoding enzymes involved in hydroxylation of Asn(3) and methoxylation of Asp(9). The chemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::583bbffeeb9dabcfbf81fd163537ecbe
https://pubmed.ncbi.nlm.nih.gov/21102593
https://pubmed.ncbi.nlm.nih.gov/21102593