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pro vyhledávání: '"Jian-Qi Ju"'
Autor:
Wen Si, Ying-Ying Fan, Shi-Zhen Qiu, Xin Li, Er-Yi Wu, Jian-Qi Ju, Wen Huang, Hao-Peng Wang, Ping Wei
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106529- (2023)
Summary: Chimeric antigen receptor (CAR)-T cells have shown great promise in cancer therapy. However, the anti-tumor efficiency is limited due to the CAR-induced T cell apoptosis or exhaustion. The intracellular domain of CAR comprised of various sig
Externí odkaz:
https://doaj.org/article/929a8eb89d3e41c5952b77b1b7c99966
Autor:
Yu-Xi Ke, Wendell A. Lim, Qiu-Yue Wang, Zhi-Bo Zhang, Chao Tang, Jian-Qi Ju, Ping Wei, Shi-Yu Liu
Publikováno v:
Cell systems. 5(5)
Summary Although oscillatory circuits are prevalent in transcriptional regulation, it is unclear how a circuit's structure and the specific parameters that describe its components determine the shape of its oscillations. Here, we engineer a minimal,