Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Jian-Kang CHEN"'
Publikováno v:
Guoji Yanke Zazhi, Vol 13, Iss 9, Pp 1758-1761 (2013)
AIM: To study the effects of estrogen on the expression of matrix metalloproteinases-1(MMP-1)and tissue inhibitor of matrix metalloproteinase-1(TIMP-1)in lacrimal gland of ovariectomized rat. METHODS:A total of 60 female rats were examined for the ex
Externí odkaz:
https://doaj.org/article/4a0a97dd28cf405082012846e8972378
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0113130 (2015)
The cytochrome P450 epoxygenase-dependent arachidonic acid metabolites, epoxyeicosatrienoic acids (EETs), are potent survival factors and mitogens for renal epithelial cells, but the molecular identity in the cells that initiates the mitogenic signal
Externí odkaz:
https://doaj.org/article/87c6db19581d4c45b0a314eae6df6998
Autor:
Bao-Ying Chen, Jian-Kang Chen, Miao-Zhang Zhu, Dong-Liang Zhang, Jie-Shen Sun, Jian-Ming Pei, Hua-Song Feng, Xiao-Xing Zhu, Jian Jin, Jun Yu
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20477 (2011)
The aim of this study was to evaluate the cardiovascular and renal activities of a newly designed natriuretic peptide (NP). Here, we engineered a novel 28-amino acid chimeric peptide, termed AC-NP that combined the 17-amino acid ring of C type natriu
Externí odkaz:
https://doaj.org/article/cd1231d97b8246a487ca9db5e0002c0d
Autor:
Ting Liu, Jialing Yuan, Caihong Dai, Chen, Mystie X., Fan, Jerry, Humphreys, Benjamin D., Fulton, David J. R., Kleven, Daniel T., Xingjun Fan, Zheng Dong, Jian-Kang Chen
Publikováno v:
American Journal of Physiology: Cell Physiology; Oct2024, Vol. 327 Issue 4, pC1094-C1110, 17p
Autor:
Fang Li, Yili Fang, Qiyuan Zhuang, Meichu Cheng, Desmond Moronge, Hao Jue, Oded Meyuhas, Xiaoqiang Ding, Zhigang Zhang, Jian-Kang Chen, Huijuan Wu
Publikováno v:
Kidney International. 102:121-135
Ribosomal protein S6 (rpS6) phosphorylation mediates the hypertrophic growth of kidney proximal tubule cells. However, the role of rpS6 phosphorylation in podocyte hypertrophy and podocyte loss during the pathogenesis of focal segmental glomeruloscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9ecd4cfad6a202c1a1fa5dd0763d1d4
https://doi.org/10.1016/j.kint.2022.02.037
https://doi.org/10.1016/j.kint.2022.02.037
Autor:
Chenyang Qi, Jian Kang Chen, Feng Wang, Huijuan Wu, Zhonghua Zhao, Zhigang Zhang, Xing Mao, Yili Fang, Fang Li
Publikováno v:
Cell Death Discovery, Vol 6, Iss 1, Pp 1-16 (2020)
Cell Death Discovery
Cell Death Discovery
Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients developing polycystic kidney disease and leading to a decline of renal function. TSC is caused by loss-of-function mutations in either T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3754fed37ffba648673ab9816807659e
http://link.springer.com/article/10.1038/s41420-020-0285-0
http://link.springer.com/article/10.1038/s41420-020-0285-0
Publikováno v:
Am J Physiol Renal Physiol
Excessive compensatory nephron hypertrophy (CNH) has been implicated in setting the stage for progressive nephron damage. Lack of a class III phosphatidylinositol 3-kinase (Pik3c3) inhibitor suitable for using in animals and lack of a Pik3c3-deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384ff84997043f6c60c7703df100d012
https://doi.org/10.1152/ajprenal.00381.2019
https://doi.org/10.1152/ajprenal.00381.2019
Publikováno v:
Experimental Eye Research. 226:109306
Mouse models are valuable tools in studying lens biology and biochemistry, and the Cre-loxP system is the most used technology for gene targeting in the lens. However, numerous genes are indispensable in lens development. The conventional knockout me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c226b28fe69a0d643b124ac1933a5ea
https://doi.org/10.1016/j.exer.2022.109306
https://doi.org/10.1016/j.exer.2022.109306
Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Ultraviolet B (UVB) has been well documented to induce capsular cataracts; however, the mechanism of the lens epithelial cell–mediated repair process after UVB irradiation is not fully understood. The purpose of this study was to better und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fbf1f38613d15300955c5c41c9af6e
https://pubmed.ncbi.nlm.nih.gov/34967856
https://pubmed.ncbi.nlm.nih.gov/34967856
Autor:
Jian-Kang Chen, Zhen-Yu Wu
Publikováno v:
Soils and Foundations. 59:2299-2310
Rockfills are typically characterized by high shear strength and are extensively used in the construction of water retaining embankments. In practice, however, due to variations in the processes of quarrying and compacting of rock aggregates, the she
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10b05a602f4b2ca7b780a4078428b7cb
https://doi.org/10.1016/j.sandf.2019.08.013
https://doi.org/10.1016/j.sandf.2019.08.013