Zobrazeno 1 - 10 of 91 pro vyhledávání: '"Jian-Jun, Zou"'
1
Akademický článek
Combined angiogenesis and PD-1 inhibition for immunomodulatory TNBC: concept exploration and biomarker analysis in the FUTURE-C-Plus trial
Autor: Song-Yang Wu, Ying Xu, Li Chen, Lei Fan, Xiao-Yan Ma, Shen Zhao, Xiao-Qing Song, Xin Hu, Wen-Tao Yang, Wen-Jun Chai, Xiao-Mao Guo, Xi-Zi Chen, Yan-Hui Xu, Xiao-Yu Zhu, Jian-Jun Zou, Zhong-Hua Wang, Yi-Zhou Jiang, Zhi-Ming Shao
Publikováno v: Molecular Cancer, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Background Immune checkpoint inhibitors had a great effect in triple-negative breast cancer (TNBC); however, they benefited only a subset of patients, underscoring the need to co-target alternative pathways and select optimal patients. Herei
Externí odkaz: https://doaj.org/article/e0dbceec56ca46efaf601443a7bfe647
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2
Akademický článek
Assessment of anti-PD-(L)1 for patients with coexisting malignant tumor and tuberculosis classified by active, latent, and obsolete stage
Autor: Shan Su, Mei-Feng Ye, Xiao-Ting Cai, Xue Bai, Zhi-Hao Huang, Si-Cong Ma, Jian-Jun Zou, Yu-Xiang Wen, Li-Juan Wu, Xue-Jun Guo, Xian-Lan Zhang, Wen-Chang Cen, Duo-Hua Su, Hui-Yi Huang, Zhong-Yi Dong
Publikováno v: BMC Medicine, Vol 19, Iss 1, Pp 1-11 (2021)
Abstract Background It is not a rare clinical scenario to have patients presenting with coexisting malignant tumor and tuberculosis. Whether it is feasible to conduct programmed death-(ligand) 1 [PD-(L)1] inhibitors to these patients, especially thos
Externí odkaz: https://doaj.org/article/895224225a4443428766e35a13dfa42b
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3
Akademický článek
Alkenone surface hydrographic changes of the subarctic Northwestern Pacific since the last glacial: proxy limitations and implications of non-thermal environmental influences
Autor: Pai-Sen Yu, Chia-Ju Liao, Min-Te Chen, Jian-Jun Zou, Xuefa Shi, A. A. Bosin, Sergey A. Gorbarenko, Yusuke Yokoyama
Publikováno v: Progress in Earth and Planetary Science, Vol 7, Iss 1, Pp 1-13 (2020)
Abstract We investigated an alkenone-based sea surface temperature (SST) and the hydrographic change records of the subarctic Northwestern (NW) Pacific from the last glacial to interglacial. The core we investigated is a piston core (LV 63-41-2, 52.5
Externí odkaz: https://doaj.org/article/e0469d1c2dda44daadccbcf87568eda4
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4
Akademický článek
Physiologically-Based Pharmacokinetic-Pharmacodynamics Model Characterizing CYP2C19 Polymorphisms to Predict Clopidogrel Pharmacokinetics and Its Anti-Platelet Aggregation Effect Following Oral Administration to Coronary Artery Disease Patients With or Without Diabetes
Autor: Ru-jun Xu, Wei-min Kong, Xiao-fei An, Jian-jun Zou, Li Liu, Xiao-dong Liu
Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)
Background and Objective: Clopidogrel (CLOP) is commonly used in coronary artery disease (CAD) patients with or without diabetes (DM), but these patients often suffer CLOP resistance, especially those with diabetes. This study was aimed to develop a
Externí odkaz: https://doaj.org/article/cc87285573c64798aeaf1a5118e45def
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9
Using machine learning to predict atrial fibrillation diagnosed after ischemic stroke
Autor: Fuping Jiang, Song Lin, Nihong Chen, Xiaohan Zheng, Jian-Jun Zou, Juan Zhang, Xiaoli Cui, Junshan Zhou, Jinsong Chen, Fusang Wang
Publikováno v: International Journal of Cardiology. 347:21-27
Background Selecting best candidates for prolonged poststroke cardiac monitoring in acute ischemic stroke (AIS) patients is still challenging. We aimed to develop a machine learning (ML) model to select AIS patients at high risk of poststroke atrial
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfd78feaa78e0bfdfa08ae16f6f0ee7
https://doi.org/10.1016/j.ijcard.2021.11.005
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10
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
Autor: Jian-jun Zou, Yifan Zhang, Dafang Zhong, Xiao-fei Chen, Xin liang, Y. L. Zhu, Yan-mei Liu, Qian Chen, Hai-yan Liu, Jingying Jia, Zhendong Chen, Chen Yu, Yan Zhan
Publikováno v: Clinical Therapeutics. 43:e264-e273
Purpose Henagliflozin is a highly selective and effective sodium glucose co-transporter (SGLT)-2 inhibitor developed for the treatment of patients with type 2 diabetes mellitus (T2DM). This study aimed to investigate the effects of meal intake on the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64897d6114b818afbcc628b566b7ae6
https://doi.org/10.1016/j.clinthera.2021.07.008
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