Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jian-Jiang Hao"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Mitochondria are essential cellular organelles that participate in important cellular processes, including bioenergetics, metabolism, and signaling. Recent functional and proteomic studies have revealed the remarkable complexity of mitochondrial prot
Externí odkaz:
https://doaj.org/article/684b196d0ff64797bee0c4225d486936
Autor:
Yu-Li Song, Run Yu, Xin-Wei Qiao, Chun-Mei Bai, Chong-Mei Lu, Yu Xiao, Ding-Rong Zhong, Jie Chen, Yu-Pei Zhao, Tai-Ping Zhang, Tian-Tian Song, He-Li Gao, Ying-Hua Wan, Lin Shen, Bin Lv, Jian-Jiang Hao, Ye Zhang, Laura Tang, Yuan-Jia Chen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Prognostic biomarkers for the pancreatic neuroendocrine tumors are needed. Proteomic study on insulinoma has been rarely reported. We identified the differential expression of proteins between insulinoma and their paired tissues by proteomic
Externí odkaz:
https://doaj.org/article/cdd41ba6f50b48ae95d0ff5540b121b4
Autor:
Qingdi Quentin Li, Jian-Jiang Hao, Zheng Zhang, L. Spencer Krane, Kai H. Hammerich, Thomas Sanford, Jane B. Trepel, Len Neckers, Piyush K. Agarwal
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-20 (2017)
Abstract Heat shock protein 90 (HSP90) inhibition is an attractive strategy for cancer treatment. Several HSP90 inhibitors have shown promising effects in clinical oncology trials. However, little is known about HSP90 inhibition-mediated bladder canc
Externí odkaz:
https://doaj.org/article/d315dc00c8384dfc8ae699ecec61f833
Autor:
Yuichiro J. Suzuki, Jian-Jiang Hao
Publikováno v:
F1000Research, Vol 6 (2018)
Reactive oxygen species (ROS) play an important role in the development of various pathological conditions as well as aging. ROS oxidize DNA, proteins, lipids, and small molecules. Carbonylation is one mode of protein oxidation that occurs in respons
Externí odkaz:
https://doaj.org/article/b5bdfd62832a4f16913363516aba85ea
Autor:
Jian-Jiang Hao, John H. McVey, Yideng Liang, James H. Kurasawa, Mikhail V Ovanesov, Elena Karnaukhova, Timothy K Lee, M. Lin, Andrey G Sarafanov, Svetlana A Shestopal
Publikováno v:
Journal of Thrombosis and Haemostasis. 15:709-720
Essentials Recombinant factor VIII (FVIII) is known to be expressed at a low level in cell culture. To increase expression, we used codon-optimization of a B-domain deleted FVIII (BDD-FVIII). This resulted in 7-fold increase of the expression level i
Autor:
Zheng Zhang, Zhen Tao, Yi Liu, Adam R. Metwalli, Keidren Lewi, Qingdi Quentin Li, Piyush K. Agarwal, Jian-Jiang Hao, Iawen Hsu
Publikováno v:
International Journal of Oncology
The Cancer Genome Atlas (TCGA) project recently identified the importance of mutations in chromatin remodeling genes in human carcinomas. These findings imply that epigenetic modulators might have a therapeutic role in urothelial cancers. To exploit
Autor:
Jian-Jiang Hao, Yuichiro J. Suzuki
Publikováno v:
F1000Research
Reactive oxygen species (ROS) play an important role in the development of various pathological conditions as well as aging. ROS oxidize DNA, proteins, lipids, and small molecules. Carbonylation is one mode of protein oxidation that occurs in respons
Autor:
Piyush K. Agarwal, Zheng Zhang, Kai H. Hammerich, L. Spencer Krane, Jane B. Trepel, Jian-Jiang Hao, Qingdi Quentin Li, Len Neckers, Thomas Sanford
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-20 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-20 (2017)
Heat shock protein 90 (HSP90) inhibition is an attractive strategy for cancer treatment. Several HSP90 inhibitors have shown promising effects in clinical oncology trials. However, little is known about HSP90 inhibition-mediated bladder cancer therap
Autor:
Xiaofei Zhi, Quhui Wang, Zhijie Tang, Zeyu Hao, Rong Ye, Jianwei Zhu, Jian-Jiang Hao, Fei Qian, Zheng Zhang, Yeming Wang
Publikováno v:
Scientific Reports
The global change in protein abundance in colorectal cancer (CRC) and its contribution to tumorigenesis have not been comprehensively analyzed. In this study, we conducted a comprehensive proteomic analysis of paired tumors and adjacent tissues (AT)
Autor:
Yu-Li Song, Run Yu, Xin-Wei Qiao, Chun-Mei Bai, Chong-Mei Lu, Yu Xiao, Ding-Rong Zhong, Jie Chen, Yu-Pei Zhao, Tai-Ping Zhang, Tian-Tian Song, He-Li Gao, Ying-Hua Wan, Lin Shen, Bin Lv, Jian-Jiang Hao, Ye Zhang, Laura Tang, Yuan-Jia Chen
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Prognostic biomarkers for the pancreatic neuroendocrine tumors are needed. Proteomic study on insulinoma has been rarely reported. We identified the differential expression of proteins between insulinoma and their paired tissues by proteomic analysis