Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jian-Hui Shi"'
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33278- (2024)
Arginase, an enzyme dependent on manganese (Mn), plays a crucial role in the production of urea and processing of ammonia in the liver. Previous studies have shown that overconsumption of fructose disrupts Mn homeostasis in the liver of male mice. Ho
Externí odkaz:
https://doaj.org/article/70c84fbbe1a549de8bad129ddb47ba1d
Autor:
Jian-Hui Shi, Yu-Xia Chen, Yingying Feng, Xiaohang Yang, Jie Lin, Ting Wang, Chun-Chun Wei, Xian-Hua Ma, Rui Yang, Dongmei Cao, Hai Zhang, Xiangyang Xie, Zhifang Xie, Weiping J. Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Arginase, a manganese (Mn)-dependent enzyme, is indispensable for urea generation and ammonia disposal in the liver. The potential role of fructose in Mn and ammonia metabolism is undefined. Here we demonstrate that fructose overconsumption
Externí odkaz:
https://doaj.org/article/014ff36b029a4ce38946bd821c2f6fce
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Although hydrate-based technology has been considered as a safe and environmentally friendly approach for gas storage and transportation in recent decades, there are still inherent problems during hydrate production, such as a long induction time, sl
Externí odkaz:
https://doaj.org/article/e3d0a1f92521443397ed531d8f555f98
Autor:
Jian-Hui Shi, 釋堅慧
100
There are two kinds of vow system in Buddhism, i.e. Śrāvaka and Bodhisattva vow systems respectively. Bodhisattva vow is the precept the Enlightened One expounds for the disciple whose capacity is appropriate to raise bodhicitta （the min
There are two kinds of vow system in Buddhism, i.e. Śrāvaka and Bodhisattva vow systems respectively. Bodhisattva vow is the precept the Enlightened One expounds for the disciple whose capacity is appropriate to raise bodhicitta （the min
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/85114715676572333649
Autor:
Xiaojing Wu, Xian-Hua Ma, Jie Lin, Xiaohang Yang, Jian-Hui Shi, Zhifang Xie, Yu-Xia Chen, Weiping J Zhang
Publikováno v:
Life Metabolism. 2
Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is an independent risk factor for atherosclerotic cardiovascular disease. Niemann-Pick C1-like 1 (NPC1L1) is a major membrane protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e232f2d617809cbf25120a522599c57
https://doi.org/10.1093/lifemeta/load011
https://doi.org/10.1093/lifemeta/load011
Autor:
Chunchun Wei, Ping Wang, Qi Dong, Xian-Hua Ma, Ming Lu, Shasha Qi, Jian-Hui Shi, Zhifang Xie, An-Jing Ren, Weiping J. Zhang
Publikováno v:
International Journal of Obesity. 46:1068-1075
Brown adipose tissue (BAT) plays a critical role in energy expenditure by uncoupling protein 1 (UCP1)-mediated thermogenesis and represents an important therapeutic target for metabolic diseases. Carbohydrate response element-binding protein (ChREBP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cf899b2b85ebeff10f9ccbcf2a649d1
https://doi.org/10.1038/s41366-022-01082-7
https://doi.org/10.1038/s41366-022-01082-7
Autor:
Jian-Hui Shi, Hai Zhang, Chun-Chun Wei, Dongmei Cao, Yu-Xia Chen, Fang-Zhen Xia, Yingli Lu, Ya-Nan Shi, Guanghou Shui, Sin Man Lam, Xia Yang, Xiongfei Xu, Heng-Yu Chen, Weiping J. Zhang, Jun-Yu Lu, Qiufang Bai, Hao Li, Liming Chen
Publikováno v:
Diabetes. 69(4)
Excessive fructose consumption is closely linked to the pathogenesis of metabolic disease. Carbohydrate response element-binding protein (ChREBP) is a transcription factor essential for fructose tolerance in mice. However, the functional significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003363192d98e173cba9706c4fa046b6
https://pubmed.ncbi.nlm.nih.gov/31974143
https://pubmed.ncbi.nlm.nih.gov/31974143
Autor:
Jian-Hui Shi, Ying-Jie Hao
Publikováno v:
Biochemical and biophysical research communications. 510(4)
Osteosarcoma (OS) is an invasive cancer in the skeletal system. The molecular mechanism of its etiology and pathogenesis are still not clear, so the effective treatment strategy of OS needs further research. First, we analyzed the expression level an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1000603214e11da1986e01e01954da16
https://pubmed.ncbi.nlm.nih.gov/30738579
https://pubmed.ncbi.nlm.nih.gov/30738579
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Toll-like receptor (TLR) signaling plays major roles in innate immune response in macrophages. Melatonin regulates TLR3- and TLR4-mediated innate immune responses in macrophages. However, it remains unknown whether melatonin regulates TLR9-mediated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99aa98c7904da5537b48ec00698ae2ca
https://doi.org/10.1038/s41598-018-34011-8
https://doi.org/10.1038/s41598-018-34011-8
Autor:
Xiongfei Xu, Kejia Wang, An-Jing Ren, Yu-Xia Chen, Xianhua Ma, Jian-Hui Shi, Xuchao Jiang, Hai Zhang, Shaodong Guo, Jianming Zheng, Jun-Yu Lu, Hui Jiang, Weiping J. Zhang, Zhifang Xie
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 5, Pp 1-11 (2018)
Cell Death and Disease, Vol 9, Iss 5, Pp 1-11 (2018)
Liver has a unique regenerative capacity, however, its regulatory mechanism is not fully defined. We have established the zinc-finger protein ZBTB20 as a key transcriptional repressor for alpha-fetoprotein (AFP) gene in liver. As a marker of hepatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edee9ddb48fbb3c7dcfd54abe7873f0
https://pubmed.ncbi.nlm.nih.gov/29700307
https://pubmed.ncbi.nlm.nih.gov/29700307