Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jian-Guo Ren"'
Publikováno v:
Frontiers in Materials, Vol 11 (2024)
This paper explored the effects of various amounts of cellulose nanocrystals (CNCs), namely 0%, 0.1%, 0.2%, and 0.4% of binder weight, on the rheology, pore structure, mechanical properties, and 3D distribution of fibers of an engineered cementitious
Externí odkaz:
https://doaj.org/article/1cb21775f4e7421585ee1ee5b4eb7cd7
Autor:
Seyed Pairawan, Ming Zhao, Erkan Yuca, Allen Annis, Kurt Evans, David Sutton, Luis Carvajal, Jian-Guo Ren, Solimar Santiago, Vincent Guerlavais, Argun Akcakanat, Coya Tapia, Fei Yang, Priya Subash Chandra Bose, Xiaofeng Zheng, Ecaterina Ileana Dumbrava, Manuel Aivado, Funda Meric-Bernstam
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Background MDM2/MDMX proteins are frequently elevated in hormone receptor-positive (ER+) breast cancer. We sought to determine the antitumor efficacy of the combination of ALRN-6924, a dual inhibitor of MDM2/MDMX, with chemotherapy in ER+ br
Externí odkaz:
https://doaj.org/article/c251cacd8a6e4763988dbd3811b83598
Autor:
Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua Dempster, Mark Murakami, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Nicolas A. Cordero, Kristen E. Stevenson, Maneka Puligandla, Brian Haas, Christopher Lo, Robin Meyers, Galen Gao, Andrew Cherniack, Abner Louissaint, Valentina Nardi, Aaron R. Thorner, Henry Long, Xintao Qiu, Elizabeth A. Morgan, David M. Dorfman, Danilo Fiore, Julie Jang, Alan L. Epstein, Ahmet Dogan, Yanming Zhang, Steven M. Horwitz, Eric D. Jacobsen, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, D. Allen Annis, Manuel Aivado, Mansoor N. Saleh, Amitkumar Mehta, Aviad Tsherniak, David Root, Francisca Vazquez, William C. Hahn, Giorgio Inghirami, Jon C. Aster, David M. Weinstock, Raphael Koch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
T- and NK-cell lymphomas (TCL) are a group of lymphoid malignancies characterized by poor prognosis, but the absence of appropriate pre-clinical models has hampered the development of effective therapies. Here the authors establish several pre-clinic
Externí odkaz:
https://doaj.org/article/ecc83cf960564bd2938fc055d45d8a01
Autor:
Jian-Guo Ren, Pankaj Seth, Huihui Ye, Kun Guo, Jun-ichi Hanai, Zaheed Husain, Vikas P. Sukhatme
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract In this study we have tested the efficacy of citrate therapy in various cancer models. We found that citrate administration inhibited A549 lung cancer growth and additional benefit accrued in combination with cisplatin. Interestingly, citrat
Externí odkaz:
https://doaj.org/article/3acbcb82668747168191a6e029a8aad7
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Malic enzyme 2 (ME2) is a mitochondrial enzyme that catalyzes the conversion of malate to pyruvate and CO2 and uses NAD as a cofactor. Higher expression of this enzyme correlates with the degree of cell de-differentiation. We found that ME2 is expres
Externí odkaz:
https://doaj.org/article/b6e91d2209f1407cb38136e0d4f603c4
Autor:
Vincent Guerlavais, David Sutton, Argun Akcakanat, Manuel Aivado, Fei Yang, Ecaterina Ileana Dumbrava, Kurt W. Evans, Funda Meric-Bernstam, A. Annis, Seyed Pairawan, Luis A. Carvajal, Ming Zhao, Solimar Santiago, Erkan Yuca, Priya Subash Chandra Bose, Coya Tapia, Jian-Guo Ren, Xiaofeng Zheng
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background MDM2/MDMX proteins are frequently elevated in hormone receptor-positive (ER+) breast cancer. We sought to determine the antitumor efficacy of the combination of ALRN-6924, a dual inhibitor of MDM2/MDMX, with chemotherapy in ER+ breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cc7c381261de8792d01829c74d7695
https://doaj.org/article/c251cacd8a6e4763988dbd3811b83598
https://doaj.org/article/c251cacd8a6e4763988dbd3811b83598
Publikováno v:
Ocean Engineering. 266:112944
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e8cf4a1517fdfd92cc7e85e6ac8d875
https://doi.org/10.1016/j.oceaneng.2022.112944
https://doi.org/10.1016/j.oceaneng.2022.112944
Autor:
Ashweta Sahni, George Appiah Kubi, Ziqing Qian, Jian-Guo Ren, Amritendu Koley, Patrick G Dougherty, Jin Wen, Ruchira Basu, Xiaoyan Pan, Dehua Pei, Heba Salim
Publikováno v:
J Med Chem
Stapled peptides recapitulate the binding affinity and specificity of α-helices in proteins, resist proteolytic degradation, and may provide a novel modality against challenging drug targets such as protein-protein interactions. However, most of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8209ea802cefe2b26a8c964426c9034b
https://doi.org/10.1021/acs.jmedchem.9b00456
https://doi.org/10.1021/acs.jmedchem.9b00456
Autor:
Qian Zhang, Chang fei Wang, Yu jing Sun, Jian guo Ren, Xin jian Chang, Yao yong Wang, Dong yan Li, Ying Wang, Jian hua Wu
Publikováno v:
Infectious Diseases
Introduction: With the emergence of novel coronavirus disease 2019 (COVID-19) in many countries, medical resources currently focus on the treatment of confirmed patients and screening of suspected cases. Asymptomatic patients may be contagious, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ccdcea0190a0843ff6a26cfe6e53767
Autor:
Yujing Sun, Yao Tian, Yaoyong Wang, Changfei Wang, Jianhua Wu, Jian guo Ren, Dongyan Li, Ying Wang, Qian Zhang, Yanwen Gao, Xiaofei Zhang, Xinjian Chang
Background: With the emergence of coronavirus disease 2019 in many places around the world, the main medical resources currently focus on the treatment of confirmed patients and the screening of suspected cases. Asymptomatic patients are difficult to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba1255dce7b3d4f1933a8530a83a85a3
https://doi.org/10.21203/rs.3.rs-22292/v1
https://doi.org/10.21203/rs.3.rs-22292/v1
