Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Jian hui Wu"'
Autor:
Tahar Aboulkassim, Xiaohong Tian, Qiang Liu, Dinghong Qiu, Mark Hancock, Jian Hui Wu, Gerald Batist
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113104- (2023)
Summary: NRF2 (nuclear factor erythroid 2-related factor 2) is a master regulator of protective responses in healthy tissues. However, when it is active in tumor cells, it can result in drug resistance. KEAP1, the endogenous NRF2 inhibitor, binds NRF
Externí odkaz:
https://doaj.org/article/5432f75a297e4e659b80fb929a830c8e
Autor:
Lin Lin Song, Yuan Qing Qu, Yong Pei Tang, Xi Chen, Hang Hong Lo, Li Qun Qu, Yun Xiao Yun, Vincent Kam Wai Wong, Rui Long Zhang, Hui Miao Wang, Meng Han Liu, Wei Zhang, Hui Xia Zhang, Joyce Tsz Wai Chan, Cai Ren Wang, Jian Hui Wu, Betty Yuen Kwan Law
Publikováno v:
Redox Biology, Vol 61, Iss , Pp 102637- (2023)
Alzheimer's disease is a neurodegenerative disorder characterized by a decline in cognitive function. The β-amyloid (Aβ) hypothesis suggests that Aβ peptides can spontaneously aggregate into β-fragment-containing oligomers and protofibrils, and t
Externí odkaz:
https://doaj.org/article/4bfba4f3628f4c24a2fa823dc311d728
Autor:
Jinming Zhou, Jian Hui Wu
Publikováno v:
Molecules, Vol 25, Iss 8, p 1821 (2020)
Multi-target ligand strategies provide a valuable method of drug design. However, to develop a multi-target drug with the desired profile remains a challenge. Herein, we developed a computational method binding-site match maker (BSMM) for the design
Externí odkaz:
https://doaj.org/article/75aef09a6ced430db025c5d2621f6907
Autor:
Alexandre Sze, David Olagnier, Samar Bel Hadj, Xiaoying Han, Xiao Hong Tian, Hong-Tao Xu, Long Yang, Qingwen Shi, Penghua Wang, Mark A. Wainberg, Jian Hui Wu, Rongtuan Lin
Publikováno v:
Viruses, Vol 9, Iss 10, p 287 (2017)
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in humans, and the former are emerging as global health concerns with no antiviral treatments. We investigated Sophora Flavecens, used in Chinese medicine, as a sou
Externí odkaz:
https://doaj.org/article/906732291e9c425988c75bbc0a34e75f
Publikováno v:
BMC Medical Imaging, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Purpose Retroperitoneal liposarcoma (RLPS) poses a challenging scenario for surgeons due to its unpredictable biological behavior. Surgery remains the primary curative option for RLPS; however, the need for additional information to guide su
Externí odkaz:
https://doaj.org/article/890f43520e5f4ffd8f8c3e62ea7aee4f
Autor:
Zhen Wang, Jian-hui Wu, Cheng-peng Li, Ang Lv, Hui Qiu, Xiu-yun Tian, Bo-nan Liu, Chun-yi Hao
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
The outcomes of patients with primary retroperitoneal sarcoma (RPS) are significantly superior to those with recurrence. En bloc resection of tumor and adjacent organs is recommended in primary RPS. However, whether en bloc resection of tumor and adj
Externí odkaz:
https://doaj.org/article/07dcfe2efbfc4ae6934a4e3f144e1ea2
Publikováno v:
BMC Urology, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Ureteric stricture is a common and salvaging complications after renal transplantation. Two treatment methods are usually used, retrograde ureteral stent placement and percutaneous nephrostomy. The former has a higher failure rate
Externí odkaz:
https://doaj.org/article/b077d37d0ffe4c2baed2e69e2344a48d
Autor:
Qianhui Yi, Weiguo Liu, Jung Hwa Seo, Jie Su, Moulay A. Alaoui-Jamali, Jun Luo, Rongtuan Lin, Jian Hui Wu
Publikováno v:
Molecular Cancer Therapeutics. 22:570-582
The current mainstay therapeutic strategy for advanced prostate cancer is to suppress androgen receptor (AR) signaling. However, castration-resistant prostate cancer (CRPC) invariably arises with restored AR signaling activity. To date, the AR ligand
Autor:
Muhammad Musa Khan, Ze-Yun Fan, Irfan Ali Sabir, Muhammad Hafeez, Sang Wen, Jian-Hui Wu, Bao-Li Qiu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9800 (2022)
Ultraviolet-C (UV-C) radiation significantly impacts living organisms. UV-C radiation can also be used as a pest management tool. Therefore, this study was designed to investigate the effect of UV-C radiation on the physiology and gene expression lev
Externí odkaz:
https://doaj.org/article/e54991c5c26643b5805a0730f8da3a60
Autor:
Cheng-Peng Li, Zhen Wang, Bo-Nan Liu, Ang Lv, Dao-Ning Liu, Jian-Hui Wu, Hui Qiu, Chun-Yi Hao
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
BackgroundEn bloc resection of retroperitoneal sarcoma (RPS) with adjacent organs such as pancreatic head and duodenum is challenging for surgeons. This mono-institutional study aims to evaluate the feasibility, safety, and outcome of performing panc
Externí odkaz:
https://doaj.org/article/795b5533d49b4438a91615e2801426d5