Zobrazeno 1 - 10
of 358
pro vyhledávání: '"Jian R Lu"'
Autor:
Kai Qi, Hao Qi, Muhan Wang, Xiaoyue Ma, Yan Wang, Qiang Yao, Wenliang Liu, Yurong Zhao, Jiqian Wang, Yuefei Wang, Wei Qi, Jun Zhang, Jian R. Lu, Hai Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Although hydrophobic interactions provide the main driving force for initial peptide aggregation, their role in regulating suprastructure handedness of higher-order architectures remains largely unknown. We here interrogate the effects of hy
Externí odkaz:
https://doaj.org/article/5763b354ed4c49e7b5d776d13285b645
Autor:
Conor M. Lewis, Charles T. Heise, Natalia Harasimiuk, Jennifer Tovey, Jian R. Lu, Thomas A. Waigh
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026105-026105-8 (2024)
The viscoelasticity of monoclonal antibodies (mAbs) is important during their production, formulation, and drug delivery. High concentration mAbs can provide higher efficacy therapeutics (e.g., during immunotherapy) and improved efficiency during the
Externí odkaz:
https://doaj.org/article/3f9f7e7dde6947139450411208214f3a
Publikováno v:
APL Bioengineering, Vol 8, Iss 2, Pp 026128-026128-18 (2024)
Monoclonal antibodies (mAbs) can undergo structural changes due to interaction with oil–water interfaces during storage. Such changes can lead to aggregation, resulting in a loss of therapeutic efficacy. Therefore, understanding the microscopic mec
Externí odkaz:
https://doaj.org/article/dd0adc7a83ab4e399acb0a2c01e1fa80
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60645 (2013)
BACKGROUND: Microbial derived lipolytic hydrolysts are an important class of biocatalysts because of their huge abundance and ability to display bioactivities under extreme conditions. In spite of recent advances, our understanding of these enzymes r
Externí odkaz:
https://doaj.org/article/821eef6ae69d4ca6a2914b63fc64f87f
Autor:
Xiaoqiang Wang, Guihong Huang, Daoyong Yu, Baosheng Ge, Jiqian Wang, Fengxi Xu, Fang Huang, Hai Xu, Jian R Lu
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76256 (2013)
It is difficult to maintain a target membrane protein in a soluble and functional form in aqueous solution without biological membranes. Use of surfactants can improve solubility, but it remains challenging to identify adequate surfactants that can i
Externí odkaz:
https://doaj.org/article/e860eb52c33e4588b0c30331ab1c90e3
Autor:
Jiqian Wang, Gang Meng, Kai Tao, Min Feng, Xiubo Zhao, Zhen Li, Hai Xu, Daohong Xia, Jian R Lu
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43478 (2012)
BACKGROUND: Biocatalytic processes often require a full recycling of biocatalysts to optimize economic benefits and minimize waste disposal. Immobilization of biocatalysts onto particulate carriers has been widely explored as an option to meet these
Externí odkaz:
https://doaj.org/article/71bab5d7310e42ad82c780f58309f003
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e6980 (2009)
BACKGROUND:Halophiles are extremophiles that thrive in environments with very high concentrations of salt. Although the salt reliance and physiology of these extremophiles have been widely investigated, the molecular working mechanisms of their enzym
Externí odkaz:
https://doaj.org/article/ed2801382da340fe820f7cb8f7dae9f7
Autor:
Rhona E McDonald, Rachel I Fleming, John G Beeley, Douglas L Bovell, Jian R Lu, Xiubo Zhao, Alan Cooper, Malcolm W Kennedy
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5726 (2009)
Horses are unusual in producing protein-rich sweat for thermoregulation, a major component of which is latherin, a highly surface-active, non-glycosylated protein. The amino acid sequence of latherin, determined from cDNA analysis, is highly conserve
Externí odkaz:
https://doaj.org/article/a7731993606f4ee79949f9c5860b0208
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5627 (2009)
BACKGROUND: Most low molecular diols are highly water-soluble, hygroscopic, and reactive with many organic compounds. In the past decades, microbial research to produce diols, e.g. 1,3-propanediol and 2,3-butanediol, were considerably expanded due to
Externí odkaz:
https://doaj.org/article/5a057564b267459fa25e4ffbb7e480e8
Publikováno v:
Global Challenges, Vol 7, Iss 2, Pp n/a-n/a (2023)
Abstract Zinc oxide, as a commonly used photocatalytic degradation of organic pollutants, typically shows limitations in wastewater treatment, such as aggregation and recycling problems caused by nanoscale dimensions and inappropriate substrates. Anc
Externí odkaz:
https://doaj.org/article/d5920c5ff8b74a77ac43e8823dc0e190