Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Jian Ming Ren"'
Autor:
Jianjie Ma, Jian-Ming Ren, Shi-Jin Zhang, Abram Katz, Marie E. Sandström, Maria Ahlsén, Håkan Westerblad, Niklas Ivarsson, Hua Zhu
Publikováno v:
Experimental Physiology. 95:892-898
2-Methoxyoestradiol (2-ME) is an oestrogen derivative that inhibits superoxide dismutase (which converts superoxide anions to H2O2). Since reactive oxygen species have been implicated in glucose transport, we determined the effect of 2-ME on glucose
Autor:
Irene K. Moore, Gerald I. Shulman, Raynald Bergeron, Marc Pypaert, Jian Ming Ren, Kevin S. Cadman, Pascale Perret, Lawrence H. Young, Clay F. Semenkovich
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
The underlying mechanism by which skeletal muscle adapts to exercise training or chronic energy deprivation is largely unknown. To examine this question, rats were fed for 9 wk either with or without beta-guanadinopropionic acid (beta-GPA; 1% enriche
Autor:
Kevin S. Cadman, Sylvie Dufour, Beat M. Jucker, Gerald I. Shulman, Xueying Cao, Jian-Ming Ren, Stephen F. Previs
Publikováno v:
Journal of Biological Chemistry. 275:39279-39286
To examine the relationship between mitochondrial energy coupling in skeletal muscle and change in uncoupling protein 3 (UCP3) expression during the transition from the fed to fasted state, we used a novel noninvasive31P/13C NMR spectroscopic approac
Autor:
Kevin S. Cadman, Xueying Cao, Jian-Ming Ren, Beat M. Jucker, Sylvie Dufour, Stephen F. Previs, Gerald I. Shulman, Brian Underhill
Publikováno v:
Proceedings of the National Academy of Sciences. 97:6880-6884
The recently cloned uncoupling protein homolog UCP3 is expressed primarily in muscle and therefore may play a significant role in the regulation of energy expenditure and body weight. However, investigation into the regulation of uncoupling protein h
Autor:
Bess A. Marshall, Nicole Barucci, Polly A. Hansen, Jian-Ming Ren, Gerald I. Shulman, Mike Mueckler
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 278:E588-E592
The purpose of the present study was to determine the rates of muscle glycogenolysis and glycogenesis during and after exercise in GLUT-1 transgenic mice and their age-matched littermates. Male transgenic mice (TG) expressing a high level of human GL
Autor:
Lawrence H. Young, Raymond R. Russell, Michael J. Caplan, Jian-Ming Ren, Gerald I. Shulman, Raynald Bergeron, Albert J. Sinusas, Renfu Yin
Publikováno v:
The American Journal of Cardiology. 83:25-30
Myocardial glucose utilization increases in response to the energetic stress imposed on the heart by exercise, pressure overload, and myocardial ischemia. Recruitment of glucose transport proteins is the cellular mechanism by which the heart increase
Autor:
Yitao Zhang, Julio Sanchez Gutierrez, Sebastian Pons, Morris F. White, Dominic J. Withers, Stephen F. Previs, Gerald I. Shulman, Susan Bonner-Weir, Dolores Bernal, Heather H. Towery, Jian-Ming Ren, Deborah J. Burks
Publikováno v:
ResearcherID
Human type 2 diabetes is characterized by defects in both insulin action and insulin secretion. It has been difficult to identify a single molecular abnormality underlying these features. Insulin-receptor substrates (IRS proteins) may be involved in
Autor:
Jian-Ming Ren, Dominic Langley, Abram Katz, Pavel Shashkin, Aleksei Koshkin, Håkan Westerblad
Publikováno v:
Journal of Biological Chemistry. 270:25613-25618
The role of calmoudulin in control of carbohydrate metabolism in the absence and presence of insulin in isolated mouse soleus muscle was investigated. The calmodulin antagonist CGS 9343B had no effect on basal glycogen synthase activity, the contents
Publikováno v:
Pfl�gers Archiv European Journal of Physiology. 430:389-393
Administration of beta-guanidinopropionic acid (beta-GPA) to rats as 1% of their diet for 6 weeks led to an accumulation of beta-GPA and beta-GPA-phosphate and to a depletion of creatine and phosphocreatine in the fast-twitch plantaris muscle. Adenos
Publikováno v:
Journal of Clinical Investigation. 95:429-432
The effect of increased Glut4 protein expression in muscle and fat on the whole body glucose metabolism has been evaluated by the euglycemic hyperinsulinemic clamp technique in conscious mice. Fed and fasting plasma glucose concentrations were 172 +/