Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jian Ming Khor"'
Autor:
Jian Ming Khor, Charles A Ettensohn
Publikováno v:
eLife, Vol 11 (2022)
The gene regulatory network (GRN) that underlies echinoderm skeletogenesis is a prominent model of GRN architecture and evolution. KirrelL is an essential downstream effector gene in this network and encodes an Ig-superfamily protein required for the
Externí odkaz:
https://doaj.org/article/1b9ac13785c440b78c2dcb85414fbbb7
Autor:
Jian Ming Khor, Charles A. Ettensohn
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Members of the alx gene family encode transcription factors that contain a highly conserved Paired-class, DNA-binding homeodomain, and a C-terminal OAR/Aristaless domain. Phylogenetic and comparative genomic studies have revealed complex patterns of
Externí odkaz:
https://doaj.org/article/f5732100cf8f4ba19bf13f52c2e04044
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background The developmental gene regulatory network (GRN) that underlies skeletogenesis in sea urchins and other echinoderms is a paradigm of GRN structure, function, and evolution. This transcriptional network is deployed selectively in sk
Externí odkaz:
https://doaj.org/article/2d05079bb1e146f3b4054ab51521993c
Autor:
Jian Ming Khor, Charles A Ettensohn
Publikováno v:
eLife, Vol 6 (2017)
Alx1 is a pivotal transcription factor in a gene regulatory network that controls skeletogenesis throughout the echinoderm phylum. We performed a structure-function analysis of sea urchin Alx1 using a rescue assay and identified a novel, conserved mo
Externí odkaz:
https://doaj.org/article/f2ad760a97cd4f4eaad42b49e1307bc0
Multinucleated cells, or syncytia, are found in diverse taxa. Their biological function is often associated with the compartmentalization of biochemical or cellular activities within the syncytium. How such compartments are generated and maintained i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4b673917da591100c79ee368640a58
https://doi.org/10.1101/2023.03.22.533866
https://doi.org/10.1101/2023.03.22.533866
Autor:
Jian Ming Khor, Charles A. Ettensohn
Sea urchins and other echinoderms are important experimental models for studying developmental processes. The lack of approaches for conditional gene perturbation, however, has made it challenging to investigate the late developmental functions of ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56edf5c85eae91c78ac4b5d7a4132429
https://doi.org/10.1101/2022.10.12.511941
https://doi.org/10.1101/2022.10.12.511941
Publikováno v:
Genome Research. 31:1680-1692
We used capped analysis of gene expression with sequencing (CAGE-seq) to profile eRNA expression and enhancer activity during embryogenesis of a model echinoderm: the sea urchin, Strongylocentrotus purpuratus. We identified more than 18,000 enhancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b34b9dd7300770e3de320d447f142c
https://doi.org/10.1101/gr.275684.121
https://doi.org/10.1101/gr.275684.121
Publikováno v:
Current topics in developmental biology. 146
The skeleton-forming cells of sea urchins and other echinoderms have been studied by developmental biologists as models of cell specification and morphogenesis for many decades. The gene regulatory network (GRN) deployed in the embryonic skeletogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6475d6bb954567c0bce99d0312046fe2
https://pubmed.ncbi.nlm.nih.gov/35152981
https://pubmed.ncbi.nlm.nih.gov/35152981
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128171875
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e81a1b08091b2120bac7f1f3346d74a0
https://doi.org/10.1016/bs.ctdb.2021.10.005
https://doi.org/10.1016/bs.ctdb.2021.10.005