Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Jian Jun Wei"'
Autor:
Kadir Buyukcelebi, Xintong Chen, Fatih Abdula, Hoda Elkafas, Alexander James Duval, Harun Ozturk, Fidan Seker-Polat, Qiushi Jin, Ping Yin, Yue Feng, Serdar E. Bulun, Jian Jun Wei, Feng Yue, Mazhar Adli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Nearly 70% of Uterine fibroid (UF) tumors are driven by recurrent MED12 hotspot mutations. Unfortunately, no cellular models could be generated because the mutant cells have lower fitness in 2D culture conditions. To address this, we employ
Externí odkaz:
https://doaj.org/article/f796869116f04aa3836b1d309cad5481
Autor:
Yinuo Li, Xiuhua Xu, Huma Asif, Yue Feng, Brendan F. Kohrn, Scott R. Kennedy, J. Julie Kim, Jian-Jun Wei
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-17 (2022)
Highlights High rate of MED12 mutations and leiomyoma burden are clearly associated with myometrial oxidative stress. MED12 mutations are driven by misrepair of 8-OHdG at c.130-c.131 detected by deep sequencing analysis both in vitro and in vivo.
Externí odkaz:
https://doaj.org/article/fa4d73ee827a428fb574c9eddc9efbec
Autor:
Olugbenga Akindele Silas, Fatimah Abdulkareem, Jorge Eduardo Novo, Yinan Zheng, Drew R. Nannini, Demirkan B. Gursel, Rose Anorlu, Jonah Musa, Firas H. Wehbe, Atiene S. Sagay, Folasade T. Ogunsola, Robert L. Murphy, Lifang Hou, Jian-Jun Wei
Publikováno v:
Annals of Global Health, Vol 88, Iss 1 (2022)
Inadequate pathology personnel and high cost of running a Pathology facility are factors affecting access to timely and quality pathology services in resource-constrained settings. Telepathology is a novel technology that allows Pathologists to remot
Externí odkaz:
https://doaj.org/article/2932d99f521340658c9d62bfa775811a
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/611796c441884becbfacb0dab8695250
Autor:
Jonah Musa, Kyeezu Kim, Yinan Zheng, Yishu Qu, Brian T. Joyce, Jun Wang, Drew R. Nannini, Demirkan B. Gursel, Olugbenga Silas, Fatimah B. Abdulkareem, Godwin Imade, Alani S. Akanmu, Jian-Jun Wei, Masha Kocherginsky, Kwang-Youn A. Kim, Firas Wehbe, Chad J. Achenbach, Rose Anorlu, Melissa A. Simon, Atiene Sagay, Folasade T. Ogunsola, Robert L. Murphy, Lifang Hou
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
BackgroundInvasive cervical cancer (ICC) is a serious public health burden in Nigeria, where human immunodeficiency virus (HIV) remains highly prevalent. Previous research suggested that epigenetic age acceleration (EAA) could play a role in detectio
Externí odkaz:
https://doaj.org/article/4189762c3c40486db8f9d0dfd114347b
Autor:
Brian M. Larsen, Madhavi Kannan, Lee F. Langer, Benjamin D. Leibowitz, Aicha Bentaieb, Andrea Cancino, Igor Dolgalev, Bridgette E. Drummond, Jonathan R. Dry, Chi-Sing Ho, Gaurav Khullar, Benjamin A. Krantz, Brandon Mapes, Kelly E. McKinnon, Jessica Metti, Jason F. Perera, Tim A. Rand, Veronica Sanchez-Freire, Jenna M. Shaxted, Michelle M. Stein, Michael A. Streit, Yi-Hung Carol Tan, Yilin Zhang, Ende Zhao, Jagadish Venkataraman, Martin C. Stumpe, Jeffrey A. Borgia, Ashiq Masood, Daniel V.T. Catenacci, Jeremy V. Mathews, Demirkan B. Gursel, Jian-Jun Wei, Theodore H. Welling, Diane M. Simeone, Kevin P. White, Aly A. Khan, Catherine Igartua, Ameen A. Salahudeen
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109429- (2021)
Summary: Patient-derived tumor organoids (TOs) are emerging as high-fidelity models to study cancer biology and develop novel precision medicine therapeutics. However, utilizing TOs for systems-biology-based approaches has been limited by a lack of s
Externí odkaz:
https://doaj.org/article/9e05120e2cf8481abf4978520140395c
Autor:
Ai-Min Yang, Xiuhua Xu, Yan Han, Jian-Jun Wei, Gui-Min Hao, Na Cui, Zhi-Ming Zhao, Wei Wang, Xianghua Huang
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
ObjectiveTo evaluate the risk factors for different types of pregnancy losses after embryo transfer (ET).DesignRetrospective cohort study.SettingReproductive medicine center.ParticipantsA total of 15,210 pregnancies after fresh and frozen-thawed embr
Externí odkaz:
https://doaj.org/article/bd1b0acf20d94b19962349003a001579
Autor:
Serdar E. Bulun, Sule Yildiz, Mazhar Adli, Debabrata Chakravarti, James Brandon Parker, Magdy Milad, Linda Yang, Angela Chaudhari, Susan Tsai, Jian Jun Wei, Ping Yin
Publikováno v:
Fertility and Sterility. 119:746-750
Publikováno v:
Fertility and Sterility. 119:869-882
Autor:
Wenan Qiang, Haimei Chen, Yi Yang, Andrew Crawford, Demirkan B. Gursel, Jian-Jun Wei, Thomas O’Halloran, Massimo Cristofanilli
Publikováno v:
Cancer Research. 83:P3-08
Breast cancer (BC) is a heterogeneous disease comprising different clinical, histopathological, and molecular subtypes. Triple negative breast cancer (TNBC) is among the most aggressive clinical manifestations of breast cancer (BC), and represents a