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Abstract Fungi are very common infectious pathogens, which may cause invasive and potentially life-threatening infections. However, the efficacy of antifungal medications remains limited. Herein, a Cu2+-phenolic nanoflower is designed to combat funga

Externí odkaz: https://doaj.org/article/132ad231d2b748c58a07b10b82848fbe

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Akademický článek

Herb Pair of Glycyrrhiza Radix–Platycodonis Radix Alleviates Respiratory Syncytial Virus Pneumonia in Mice by Modulating Lipid Metabolism and Inhibiting Inflammation

Autor: Yu Tang, Chen Shi, Ling Sun, Bin Yang, Jian-Jian Ji, Tong Xie, Shou-Chuan Wang, Li-Li Lin, Jin-Jun Shan

Publikováno v: World Journal of Traditional Chinese Medicine, Vol 10, Iss 3, Pp 322-333 (2024)

Objective: The objective of this study is to explore the optimal ratio of Glycyrrhiza Radix (GR, Glycyrrhizae radix et Rhizoma) and Platycodonis Radix (PR, Platycodon grandiflorum A. DC) and its potential mechanism for treating respiratory syncytial

Externí odkaz: https://doaj.org/article/5f4c091925d64ba1962f79842fb8f823

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Akademický článek

Immunocompatible elastomer with increased resistance to the foreign body response

Autor: Xianchi Zhou, Zhouyu Lu, Wenzhong Cao, Zihao Zhu, Yifeng Chen, Yanwen Ni, Zuolong Liu, Fan Jia, Yang Ye, Haijie Han, Ke Yao, Weifeng Liu, Youxiang Wang, Jian Ji, Peng Zhang

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)

Abstract Polymeric elastomers are extensively employed to fabricate implantable medical devices. However, implantation of the elastomers can induce a strong immune rejection known as the foreign body response (FBR), diminishing their efficacy. Herein

Externí odkaz: https://doaj.org/article/646ad58d401141ee93ebda0cbce2de38

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Akademický článek

ROS-responsive & scavenging NO nanomedicine for vascular diseases treatment by inhibiting endoplasmic reticulum stress and improving NO bioavailability

Autor: Jian Li, Jvhong Zhang, Pengcheng Yu, Han Xu, Meihui Wang, Zhebin Chen, Bo Yu, Jing Gao, Qiao Jin, Fan Jia, Jian Ji, Guosheng Fu

Publikováno v: Bioactive Materials, Vol 37, Iss , Pp 239-252 (2024)

Vascular diseases seriously threaten human life and health. Exogenous delivery of nitric oxide (NO) represents an effective approach for maintaining vascular homeostasis during pathological events. However, the overproduction of reactive oxygen speci

Externí odkaz: https://doaj.org/article/bedfb8ba080c407dac1b629420f9ba39

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Akademický článek

A new probabilistic model with mixed-state failure rates: Modeling time-to-event scenarios in reliability and music engineering

Autor: Xiaochun Liu, Jian Ji, Afaf Alrashidi, Fatimah A. Almulhim, Etaf Alshawarbeh, Jin-Taek Seong

Publikováno v: Alexandria Engineering Journal, Vol 96, Iss , Pp 99-111 (2024)

We consider and implement a new contemporary and state-of-the-art probabilistic model with optimal data modeling capabilities. We call the present probabilistic model a new beta power flexible Weibull distribution. It is obtained by using the flexibl

Externí odkaz: https://doaj.org/article/cb62605cbe614a119604593e9ec812f5

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