Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jian Chiuan Li"'
Autor:
Prajakta Deshpande, Chao-Yi Chen, Anuradha Venkatakrishnan Chimata, Jian-Chiuan Li, Ankita Sarkar, Catherine Yeates, Chun-Hong Chen, Madhuri Kango-Singh, Amit Singh
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Alzheimer’s disease (AD), an age-related progressive neurodegenerative disorder, exhibits reduced cognitive function with no cure to date. One of the reasons for AD is the accumulation of Amyloid-beta 42 (Aβ42) plaque(s) that trigger aber
Externí odkaz:
https://doaj.org/article/4b6bf2e90d494d1f8da8e9eec3dfcfd8
Autor:
Wei-Liang Liu, Chia-Wei Hsu, Shih-Peng Chan, Pei-Shi Yen, Matthew P. Su, Jian-Chiuan Li, Hsing-Han Li, Lie Cheng, Cheng-Kang Tang, Shih-Hsun Ko, Huai-Kuang Tsai, Zing Tsung-Yeh Tsai, Omar S. Akbari, Anna-Bella Failoux, Chun-Hong Chen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The areas where dengue virus (DENV) is endemic have expanded rapidly, driven in part by the global spread of Aedes species, which act as disease vectors. DENV replicates in the mosquito midgut and is disseminated to the mosquito’s salivary
Externí odkaz:
https://doaj.org/article/19c406fe30f44c4fa7c547a6dc2d179e
Autor:
Chih-Chieh Yu, Ferng-Chang Chang, Yong-Huei Hong, Jian-Chiuan Li, Po-Lin Chen, Chun-Hong Chen, Tzai-Wen Chiu, Tsai-Te Lu, Yun-Ming Wang, Chih-Fei Kao
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Decision-making is considered an important aspect of cognitive function. Impaired decision-making is a consequence of cognitive decline caused by various physiological conditions, such as aging and neurodegenerative diseases. Here we exploit
Externí odkaz:
https://doaj.org/article/ffd765fde7e544a691de86ad07299d6f
Autor:
Po-Lin Chen, Kai-Ting Huang, Chu-Ya Cheng, Jian-Chiuan Li, Hsiao-Yen Chan, Tzu-Yang Lin, Matthew P. Su, Wei-Yuan Yang, Henry C. Chang, Horng-Dar Wang, Chun-Hong Chen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Mitochondrial dynamics change during ageing, with larger mitochondria and altered protein import in older animals. Here the authors show that Dosmit protein mediates mitochondrial morphology with Rab32 by inducing double-membraned vesicles that regul
Externí odkaz:
https://doaj.org/article/666dd2760252480d98caf0dd4c44a027
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100432- (2021)
Summary: Implementation of CRISPR/Cas9 methodologies for mosquito gene editing has not yet become widespread. This protocol details the procedure for Aedes aegypti mosquito gene editing using homology-directed repair and fluorescent marker insertion,
Externí odkaz:
https://doaj.org/article/8d795ff22f2b4f40ae84ec4c7adbff69
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Complement-like proteins in arthropods defend against invading pathogens in the early phases of infection. Thioester-containing proteins (TEPs), which exhibit high similarity to mammalian complement C3, are thought to play a key role in the innate im
Externí odkaz:
https://doaj.org/article/5e090c9cbf984056b79b10da7bfe40a3
Autor:
Lie Cheng, Wei-Liang Liu, Yun-Ting Tsou, Jian-Chiuan Li, Chia-Hao Chien, Matthew P. Su, Kun-Lin Liu, Ya-Lang Huang, Shih-Cheng Wu, Jih-Jin Tsai, Shie-Liang Hsieh, Chun-Hong Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The C-type lectins, one family of lectins featuring carbohydrate binding domains which participate in a variety of bioprocesses in both humans and mosquitoes, including immune response, are known to target DENV. A human C-type lectin protein CLEC18A
Externí odkaz:
https://doaj.org/article/c113b8f4292240daa111bd997545a9aa
Autor:
Hsing-Han Li, Yu Cai, Jian-Chiuan Li, Matthew P. Su, Wei-Liang Liu, Lie Cheng, Shu-Jen Chou, Guann-Yi Yu, Horng-Dar Wang, Chun-Hong Chen
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101486- (2020)
Summary: Physiological trade-offs between mosquito immune response and reproductive capability can arise due to insufficient resource availability. C-type lectin family members may be involved in these processes. We established a GCTL-3−/− mutant
Externí odkaz:
https://doaj.org/article/edbd026ed0e8478c90358c7773849df3
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 8 (2020)
Maple syrup urine disease (MSUD) is an inherited error in the metabolism of branched-chain amino acids (BCAAs) caused by a severe deficiency of the branched-chain α-ketoacid dehydrogenase (BCKDH) complex, which ultimately leads to neurological disor
Externí odkaz:
https://doaj.org/article/239a50f00f7946199d4f946cf053c179
Autor:
Wei-Liang Liu, Chia-Wei Hsu, Shih-Peng Chan, Pei-Shi Yen, Matthew P. Su, Jian-Chiuan Li, Hsing-Han Li, Lie Cheng, Cheng-Kang Tang, Shih-Hsun Ko, Huai-Kuang Tsai, Zing Tsung-Yeh Tsai, Omar S. Akbari, Anna-Bella Failloux, Chun-Hong Chen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c69e1ad67d484f66b71365ec252e44eb