Zobrazeno 1 - 10
of 15 950
pro vyhledávání: '"Jian A. Li"'
Autor:
A. Clare Sparling, James M. Ward, Kakali Sarkar, Adam Schiffenbauer, Payam Noroozi Farhadi, Michael A. Smith, Saifur Rahman, Kamelia Zerrouki, Frederick W. Miller, Jian-Liang Li, Kerry A. Casey, Lisa G. Rider
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-15 (2024)
Abstract Objectives Serum protein abundance was assessed in adult and juvenile dermatomyositis (DM and JDM) patients to determine differentially regulated proteins, altered pathways, and candidate disease activity biomarkers. Methods Serum protein ex
Externí odkaz:
https://doaj.org/article/5ee387052055449bbf31c595ef8f3253
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Early evaluation of radiation sensitivity in lung cancer patients can facilitate the transition to personalized treatment strategies. To this end, we assessed the capability of 89Zr-anti-γH2AX-TAT microPET imaging in determining
Externí odkaz:
https://doaj.org/article/da5eeed6f7e64e4ea1f5c20f08047bea
Autor:
Chia-Yen Lin, Chun-Li Wang, Cheng-Kuang Yang, Jian-Ri Li, Chuan-Shu Chen, Kun-Yuan Chiu, Ching-Heng Lin, Shian-Shiang Wang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Prostate cancer (PC) treatment, particularly androgen deprivation therapy (ADT), remains pivotal, albeit linked to increased fracture risk due to osteoporosis. The advent of novel hormonal agents (NHAs) has spurred inquiries into their influ
Externí odkaz:
https://doaj.org/article/151f502bed2a49348114f19e43d30bad
NMDA receptor blockade attenuates Japanese encephalitis virus infection-induced microglia activation
Autor:
Cheng-Yi Chang, Chih-Cheng Wu, Chung-Yuh Tzeng, Jian-Ri Li, Yu-Fang Chen, Wen-Ying Chen, Yu-Hsiang Kuan, Su-Lan Liao, Chun-Jung Chen
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Neurodegeneration and neuroinflammation are key components in the pathogenesis of Japanese Encephalitis caused by Japanese Encephalitis Virus (JEV) infection. The N-methyl-D-aspartate (NMDA)-type glutamate receptor displays excitatory neurot
Externí odkaz:
https://doaj.org/article/2d61bd84790742fa947dee55c9ee68e9
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Objective Rheumatoid arthritis (RA) is a clinically heterogeneous and complex autoimmune disease, making the prediction of therapeutic responses a significant challenge. This study aims to assess the role of clinical and synovial biomarkers
Externí odkaz:
https://doaj.org/article/8eeef9049dbd4172b98f292ca4959caf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The endogenous FGF21 level is a potential target for diagnosing NAFLD. This study aimed to assess the clinical utility of FGF21 in diagnosing NAFLD and provide new ideas for predicting and preventing NAFLD. A total of 193 patients diagnosed
Externí odkaz:
https://doaj.org/article/b6f92de3bea34a8ab223a163699c3267
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4228-4242 (2024)
Cardiovascular diseases (CVDs) are a major threat to public health globally. A large proportion of people with dyslipidaemia have poorly controlled lipid levels, emphasizing the need for alternative lipid-lowering treatments that are both effective a
Externí odkaz:
https://doaj.org/article/54e0a56ceca241278621278b4dcd352a
Autor:
Tian Jian Zhou, Song Jiang, Jin Ke Ren, Xuan Zhang, Wang Xing Liu, Peng Yan, Jian Wang Li, Tong Zeng, Zhong Shi Xu
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Prompt identification of fracture healing is crucial for medical decision-making and clinical research. This study aims to assess the effectiveness of the Radiographic Union Score for Hip (RUSH) in subtrochanteric fractures and de
Externí odkaz:
https://doaj.org/article/8421296254164c33a53cb2a6fd6c74b0
Autor:
Chenyang Li, Thinh T. Nguyen, Jian-Rong Li, Xingzhi Song, Junya Fujimoto, Latasha Little, Curtis Gumb, Chi-Wan B. Chow, Ignacio I. Wistuba, Andrew P. Futreal, Jianhua Zhang, Shawna M. Hubert, John V. Heymach, Jia Wu, Christopher I. Amos, Jianjun Zhang, Chao Cheng
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-14 (2024)
Abstract Lung Cancer remains the leading cause of cancer deaths in the USA and worldwide. Non-small cell lung cancer (NSCLC) harbors high transcriptomic intratumor heterogeneity (RNA-ITH) that limits the reproducibility of expression-based prognostic
Externí odkaz:
https://doaj.org/article/b6fe0a65261748579d8ae587987a1d01
Autor:
Cheng Yang, Cheng-Gang Zhu, Yuan-Lin Guo, Na-Qiong Wu, Qian Dong, Rui-Xia Xu, Yong-Jian Wu, Jie Qian, Jian-Jun Li
Publikováno v:
Diabetes & Metabolism Journal, Vol 48, Iss 5, Pp 993-1002 (2024)
Background Endothelin-1 (ET-1) is an endogenous vasoconstrictor implicated in coronary artery disease (CAD) and diabetes. This study aimed to determine the prognostic value of ET-1 in the patients with stable CAD under different glucose metabolism st
Externí odkaz:
https://doaj.org/article/e74bf2c6e60a4ccfacb7150b3ce0f362