Zobrazeno 1 - 10
of 494
pro vyhledávání: '"Jian–Dong Jiang"'
Autor:
Qinghua Wang, Tingting Du, Zhihui Zhang, Qingyang Zhang, Jie Zhang, Wenbin Li, Jian-Dong Jiang, Xiaoguang Chen, Hai-Yu Hu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4431-4442 (2024)
Chlorogenic acid (CGA) is a natural product that effectively inhibits tumor growth, demonstrated in many preclinical models, and phase II clinical trials for patients with glioma. However, its direct proteomic targets and anticancer molecular mechani
Externí odkaz:
https://doaj.org/article/8247d7f9a4954166ba1c01e28325080e
Autor:
Tong-Tong Liu, Hai-Fei Sun, Ming-Ze Tang, Hao-Ran Shen, Zhen Shen, Yan-Xing Han, Yun Zhan, Jian-Dong Jiang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Silicosis is an irreversible fibrotic disease of the lung caused by chronic exposure to silica dust, which manifests as infiltration of inflammatory cells, excessive secretion of pro-inflammatory cytokines, and pulmonary diffuse f
Externí odkaz:
https://doaj.org/article/2b118b10efc04e819d2449e7e07a98e0
Autor:
Hu Li, Xue-Kai Wang, Mei Tang, Lei Lei, Jian-Rui Li, Han Sun, Jing Jiang, Biao Dong, Hong-Ying Li, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTGut microbiota plays an essential role in the progression of nonalcoholic fatty liver disease (NAFLD), making the gut-liver axis a potential therapeutic strategy. Bacteroides genus, the enriched gut symbionts, has shown promise in treating fa
Externí odkaz:
https://doaj.org/article/ab3b458b8c954c298ea7473b9b368c59
Autor:
Hongying Li, Jianrui Li, Jiayu Li, Hu Li, Xuekai Wang, Jing Jiang, Lei Lei, Han Sun, Mei Tang, Biao Dong, Weiqing He, Shuyi Si, Bin Hong, Yinghong Li, Danqing Song, Zonggen Peng, Yongsheng Che, Jian-Dong Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2567-2580 (2024)
The pandemic of SARS-CoV-2 worldwide with successive emerging variants urgently calls for small-molecule oral drugs with broad-spectrum antiviral activity. Here, we show that carrimycin, a new macrolide antibiotic in the clinic and an antiviral candi
Externí odkaz:
https://doaj.org/article/0c69026a221e410791cdc5a1b0b2f32b
Autor:
Jian-Dong Jiang
Publikováno v:
Engineering, Vol 38, Iss , Pp 1- (2024)
Externí odkaz:
https://doaj.org/article/dc641ba5e8d448cb86d3acfecc61fb7c
Autor:
Hailong Qi, Zhongjie Sun, Tianle Gao, Yanling Yao, Yu Wang, Weiwei Li, Xudong Wang, Xiaofang Wang, Defang Liu, Jian-Dong Jiang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-18 (2024)
Abstract Nucleic acid vaccines have shown promising potency and efficacy for cancer treatment with robust and specific T-cell responses. Improving the immunogenicity of delivered antigens helps to extend therapeutic efficacy and reduce dose-dependent
Externí odkaz:
https://doaj.org/article/12c3f4b5e99c4ee8a78a331490a652f8
Publikováno v:
Engineering, Vol 38, Iss , Pp 11-12 (2024)
Externí odkaz:
https://doaj.org/article/e2084b12175a4a7db7d14fc92912bd6e
Autor:
Zhen Shen, Yun-Dan Guo, Ming-Ze Tang, Ping Zhou, Yu-Xin Su, Hao-Ran Shen, Tao Li, Wei Jiang, Yan-Xing Han, Cai Tie, Jing-Jing Cui, Tian-Le Gao, Jian-Dong Jiang
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 803 (2024)
Pregabalin is a medication primarily used in the treatment of neuropathic pain and anxiety disorders, owing to its gabapentinoid properties. Pregabalin monotherapy faces limitations due to its variable efficacy and dose-dependent adverse reactions. I
Externí odkaz:
https://doaj.org/article/9febe5dd4fbf4ef28cdd72c6afec79b9
Autor:
Feng Wang, Yang Gao, Situ Xue, Luyao Zhao, Huimin Jiang, Tingting Zhang, Yunxuan Li, Chenxi Zhao, Fan Wu, Tana Siqin, Ying Liu, Jie Wu, Yechao Yan, Jian Yuan, Jian-dong Jiang, Ke Li
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract CSCs (Cancer stem cells) with distinct metabolic features are considered to cause HCC (hepatocellular carcinoma) initiation, metastasis and therapeutic resistance. Here, we perform a metabolic gene CRISPR/Cas9 knockout library screen in tumo
Externí odkaz:
https://doaj.org/article/9b6e3301b313436b88f6ef434ab58234
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Silicosis is a chronic illness marked by diffuse fibrosis in lung tissue resulting from continuous exposure to SiO2-rich dust in the workplace. The onset and progression of silicosis is a complicated and poorly understood pathological process involvi
Externí odkaz:
https://doaj.org/article/8066f3ee7b074408b931c433f1810875