Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jian‑Xiong Feng"'
Autor:
Li Luo, Denghui Wei, Yihui Pan, Qiu‐Xia Wang, Jian‐Xiong Feng, Bing Yu, Tiebang Kang, Junhang Luo, Jiefeng Yang, Song Gao
Publikováno v:
Cancer Communications, Vol 43, Iss 7, Pp 808-833 (2023)
Abstract Background Clear cell renal cell carcinoma (ccRCC) is the most lethal renal cancer. An overwhelming increase of patients experience tumor progression and unfavorable prognosis. However, the molecular events underlying ccRCC tumorigenesis and
Externí odkaz:
https://doaj.org/article/e670c65b26374439899838cc394c1ae4
Autor:
Yu-Jie Li, Yu-Lu Cao, Jian-Xiong Feng, Yuanbo Qi, Shuxia Meng, Jie-Feng Yang, Ya-Ting Zhong, Sisi Kang, Xiaoxue Chen, Lan Lan, Li Luo, Bing Yu, Shoudeng Chen, David C. Chan, Junjie Hu, Song Gao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Mitofusin-2 (MFN2) is a dynamin-like GTPase that plays a central role in regulating mitochondrial fusion and cell metabolism. Here, authors report crystal structures of truncated human MFN2 in different nucleotide-loading states and show that MFN2 fo
Externí odkaz:
https://doaj.org/article/20184dcb3f0a4e0db34a9f78850e0d8f
Autor:
Jin-Yu Yang, Xiang-Yu Deng, Yi-Sheng Li, Xian-Cai Ma, Jian-Xiong Feng, Bing Yu, Yang Chen, Yi-Ling Luo, Xi Wang, Mei-Ling Chen, Zhi-Xin Fang, Fu-Xiang Zheng, Yi-Ping Li, Qian Zhong, Tie-Bang Kang, Li-Bing Song, Rui-Hua Xu, Mu-Sheng Zeng, Wei Chen, Hui Zhang, Wei Xie, Song Gao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Translation inhibition is a strategy for organisms to overcome various environmental stresses including viral infections. Here the authors show that a tRNA/rRNA-targeting RNase Schlafen13 inhibits protein synthesis by directly digesting cytoplasmic t
Externí odkaz:
https://doaj.org/article/19334f8a10ad4bdb82c317e1451abf22
Autor:
Bing Yu, Jian-Xiong Feng, Li Luo, Xiao-Yan Ma, Song Gao, Jichang Wang, Hong Zhang, Jia-Li Hu, Shuang Liao, Yu-Lu Cao
Publikováno v:
Nucleic Acids Research
The stability and processing of cellular RNA transcripts are efficiently controlled via non-templated addition of single or multiple nucleotides, which is catalyzed by various nucleotidyltransferases including poly(A) polymerases (PAPs). Germline dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f86201d1d1b6d0eb249479338c2e8f1
https://doi.org/10.1093/nar/gkaa578
https://doi.org/10.1093/nar/gkaa578
Autor:
Jian Xiong Feng, Zexian Liu, Dan Xie, Chao Zhang, Jia Jia Hu, Gong Chen, Huai-Qiang Ju, Yun Xin Lu, Marcia A. Ogasawara, Ying qin Li, Yang Chen, Ying Nan Wang, Qi Zhao, Jin Ping Yun, Zhizhong Pan, Hui Chang Bi, Feng Tian, Kai Yan Liu, Ying Jin, Zhao Lei Zeng, Song Gao, Yi Ming Jiang, Scott Kopetz, Feng Wang, Jie Liu, Rui-Hua Xu, Wei Hua Jia, Hui Sheng
Publikováno v:
Oncogene
Patients with stage II or III colorectal cancer (CRC) exhibit various clinical outcomes after radical treatments. The 5-year survival rate was between 50 and 87%. However, the underlying mechanisms of the variation remain unclear. Here we show that A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c439a7909426fea7eec769d1d82a7917
https://doi.org/10.1038/s41388-019-1004-2
https://doi.org/10.1038/s41388-019-1004-2
Autor:
Ming Zhu Yang, Fang Liu, Mu Sheng Zeng, Yang Chen, Yongkang Long, Jia Li Hu, Huang-Tian Yang, Yongbo Wang, Song Gao, Jichang Wang, Jin Yu Yang, Wei Chen, Jian Xiong Feng, Nan Cao, Qian Zhong, Li Luo, Tianpeng Zhang, Shuang Liao, Xiao Yan Ma, Yong Zhao, Wei Sun, H. Y. Bai, Qingsong Gao, Bing Yu, He Liang, Hong Zhang, Peng Zhang
Publikováno v:
Nucleic Acids Research
Family with sequence similarity (FAM46) proteins are newly identified metazoan-specific poly(A) polymerases (PAPs). Although predicted as Gld-2-like eukaryotic non-canonical PAPs, the detailed architecture of FAM46 proteins is still unclear. Exact bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fd82c465e9b88eca5072f605e0100a
https://pubmed.ncbi.nlm.nih.gov/32009146
https://pubmed.ncbi.nlm.nih.gov/32009146
Autor:
Xiang Yu Deng, Yi Ling Luo, Jian Xiong Feng, Yang Chen, Wei Xie, Qian Zhong, Mu Sheng Zeng, Xiancai Ma, Mei Ling Chen, Hui Zhang, Tiebang Kang, Fu Xiang Zheng, Zhi Xin Fang, Wei Chen, Bing Yu, Xi Wang, Rui-Hua Xu, Libing Song, Jin Yu Yang, Yi Sheng Li, Song Gao, Yi-Ping Li
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Cleavage of transfer (t)RNA and ribosomal (r)RNA are critical and conserved steps of translational control for cells to overcome varied environmental stresses. However, enzymes that are responsible for this event have not been fully identified in hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2907c7d39e84b9dc2421ef3557d7bf64
http://link.springer.com/article/10.1038/s41467-018-03544-x
http://link.springer.com/article/10.1038/s41467-018-03544-x
Autor:
David C. Chan, Dong-Dong Gu, Bing Yu, Shuang Liao, Yu-Lu Cao, Yu-Jie Li, Shuxia Meng, Song Gao, Yang Chen, Jinyu Yang, Jian-Xiong Feng
Publikováno v:
Nature
Mitochondria are double-membrane organelles with varying shapes influenced by metabolic conditions, developmental stage, and environmental stimuli1–4. Their dynamic morphology is realized through regulated and balanced fusion and fission processes5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd16931dda605c29327a8a03584cf6d2
http://europepmc.org/articles/PMC5319402
http://europepmc.org/articles/PMC5319402
Publikováno v:
Experimental and Therapeutic Medicine. 12:1225-1231
Non-small cell lung cancer (NSCLC) accounts for >80% of all cases of lung cancer and can be divided into lung adenocarcinoma (LAC), large-cell carcinoma (LCC), and squamous cell carcinoma (SCC). Accumulating evidence suggests that MTSS1, which is a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af36bd9773fbe8b2eeb85f192a8d8021
https://doi.org/10.3892/etm.2016.3382
https://doi.org/10.3892/etm.2016.3382
Publikováno v:
Molecular Medicine Reports. 11:1851-1858
Clinical studies have reported evidence for the involvement of octamer‑binding protein 4 (Oct4) in the tumorigenicity and progression of lung cancer; however, the role of Oct4 in lung cancer cell biology in vitro and its mechanism of action remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17058e98f9709f607352ea4e3cd73e56
https://doi.org/10.3892/mmr.2014.2992
https://doi.org/10.3892/mmr.2014.2992