Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Jian‑Pei Fang"'
Publikováno v:
BMC Pediatrics, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Purpose The current study aims to investigate the significance of N6-methyladenosine (m6A) methylationrelated genes in the clinical prognosis of childhood relapsed B-cell acute lymphoblastic leukemia (B-ALLL) patient. Methods Transcriptome d
Externí odkaz:
https://doaj.org/article/126062dd837c4b2e863b9363f8678000
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Purpose To explore the outcome and prognostic factors between inv(16) and t(8;21) disrupt core binding factor (CBF) in acute myeloid leukemia (AML). Methods The clinical characteristic, probability of achieving complete remission (CR), overa
Externí odkaz:
https://doaj.org/article/bf1c9252028842ca9314938850774aff
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1418-1430 (2023)
Abstract Background Alterations of 11q23/KMT2A are the most prevalent cytogenetic abnormalities in acute myeloid leukemia (AML) and the prognostic significance of 11q23/KMT2A‐rearranged AML based on various translocation partners varies among diffe
Externí odkaz:
https://doaj.org/article/d28371511aae498b872cdd207332f3fc
Autor:
Kun-yin Qiu, Dun-hua Zhou, Xiong-yu Liao, Ke Huang, Yang Li, Hong-gui Xu, Wen-jun Weng, Lu-hong Xu, Jian-pei Fang
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Purpose To evaluate the prognostic factors and outcome for acute lymphoblastic leukemia (ALL) in children with MLL rearrangement (MLL-r). Methods A total of 124 pediatric patients who were diagnosed with ALL were classified into two groups b
Externí odkaz:
https://doaj.org/article/05242078cda84627a5242240d75eeb76
Autor:
Kun-yin Qiu, Shu-yi Guo, Yang-hui Zeng, Xiong-yu Liao, Shao-fen Lin, Jian-pei Fang, Dun-hua Zhou
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 874-880 (2022)
Purpose Our aim is to analyze the clinical characteristics and prognostic factors of Epstein-Barr (EB) virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) in children. Methods Children with newly diagnosed HLH were retrospectively analyzed.
Externí odkaz:
https://doaj.org/article/5547a07e08ae4381a5266a8a5b18af1d
Autor:
Xin-Yu Li, Li-Ping Zhan, Dian-Dian Liu, Xia-Wei Han, Han Chen, Zheng-Zhou Wu, Yin Wang, Li-Ping Que, Xiao-Jun Wu, Su Liu, Kai-Mei Wang, Shao-Liang Huang, Jian-Pei Fang, Ke Huang, Hong-Gui Xu
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Umbilical cord blood transplantation (UCBT) from unrelated donors is one of the successful treatments for acute leukemia in childhood. The most frequent side effect of UCBT is peri-engraftment syndrome (PES), which is directly ass
Externí odkaz:
https://doaj.org/article/f2f03d0f53b545db8cd64c21c2026643
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Immune reconstitution inflammatory syndrome (IRIS) refers to the phenomenon of intense immune responses against pathogens in patients with AIDS undergoing antiretroviral therapy to reconstitute immune function, resulting in functi
Externí odkaz:
https://doaj.org/article/6533f0b1ed2547a8bf156c4c39325b3f
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Activating FLT3 mutations are the most common mutations in AML. Here, the authors explore the relationship between the FLT3/ITD allelic ratio and prognosis in pediatric AML patients and identify an optimal threshold to stratify patients.
Externí odkaz:
https://doaj.org/article/0daa3487045a467d94b7c5d3a7e050ab
Autor:
Xin-Yu Li, Xia-Wei Han, Ke Huang, Ya-Ting Zhang, Hong-Gui Xu, Dun-Hua Zhou, Lu-Hong Xu, Jian-Pei Fang
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundThe long-term overall survival of children with T-cell acute lymphoblastic leukemia (T-ALL) is limited to approximately 80–85% because of a high incidence of relapse after achieving remission with intensive chemotherapy and hematopoietic
Externí odkaz:
https://doaj.org/article/2ef0cf310e9a4881b0a5792c1b6f31ff
Autor:
Lu-Hong Xu, Xu Geng, Ning Liao, Li-Hua Yang, Hui-Rong Mai, Wu-Qing Wan, Li-Bin Huang, Min-Cui Zheng, Chuan Tian, Hui-Qin Chen, Qi-Wen Chen, Xing-Jiang Long, Zi-Jun Zhen, Ri-Yang Liu, Qiao-Ru Li, Bei-Yan Wu, Li-Na Wang, Xian-Ling Kong, Guo-Hua Chen, Jian-Pei Fang, Yang Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesThe prognostic significance of acute lymphoblastic leukemia (ALL) patients with central nervous system leukemia (CNSL) at diagnosis is controversial. We aimed to determine the impact of CNSL at diagnosis on the clinical outcomes of childhoo
Externí odkaz:
https://doaj.org/article/44744bb0eb36457e9857f1dca5e1147d