Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Jian‑Dong Luo"'
Autor:
Qing Xiao, Xiu-Hui Chen, Ru-Chao Jiang, Sheng-Ying Chen, Kai-Feng Chen, Xiang Zhu, Xiao-ling Zhang, Jun-jun Huang, Yuan Qin, Gui-Ping Zhang, Quan Yi, Jian-dong Luo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
AimsSUMOylation is a post-translational modification that plays a crucial role in the cellular stress response. We aimed to demonstrate whether and how the SUMO E2 conjugation enzyme Ubc9 affects acute myocardial ischemic (MI) injury.Methods and Resu
Externí odkaz:
https://doaj.org/article/9055826de4a64a4e9a3de83061813b8a
Autor:
Ning Hou, Yunpei Mai, Xiaoxia Qiu, Wenchang Yuan, Yilang Li, Chengfeng Luo, Yun Liu, Guiping Zhang, Ganjiang Zhao, Jian-dong Luo
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Diabetic cardiomyopathy (DCM), a common complication of diabetes mellitus, eventually leads to heart failure. Carvacrol is a food additive with diverse bioactivities. We aimed to study the protective effects and mechanisms of carvacrol in
Externí odkaz:
https://doaj.org/article/3a2d1f3f6cfe422abb1231e3479394e9
Autor:
Xiaoqing Chen, Yilang Li, Xun Yuan, Wenchang Yuan, Conglin Li, Yue Zeng, Yuling Lian, Xiaoxia Qiu, Yuan Qin, Guiping Zhang, Xiawen Liu, Chengfeng Luo, Jian-Dong Luo, Ning Hou
Publikováno v:
Diabetes. 71(4)
Methazolamide (MTZ), a carbonic anhydrase inhibitor, has been shown to inhibit cardiomyocyte hypertrophy and exert a hypoglycemic effect in patients with type 2 diabetes mellitus and diabetic db/db mice. However, whether MTZ has a cardioprotective ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0988bed47aeec3296ea7be2b3800e7a7
https://pubmed.ncbi.nlm.nih.gov/35043173
https://pubmed.ncbi.nlm.nih.gov/35043173
Publikováno v:
Journal of Cellular Biochemistry. 119:8290-8303
Cardiac hypertrophy is one of the major risk factors for chronic heart failure. The role of endophilinA2 (EndoA2) in clathrin-mediated endocytosis and clathrin-independent endocytosis is well documented. In the present study, we tested the hypothesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::261c4fafb7f2e5ba996eb2b3e3e62727
https://doi.org/10.1002/jcb.26862
https://doi.org/10.1002/jcb.26862
Autor:
Yun Liu, Jian-Ying Xiao, Hai-Qi Liu, Xin-Qiu-Yue Wang, Jian-Dong Luo, Huan-Jia Shen, Kai-Ting Ma
Publikováno v:
Biochemical and Biophysical Research Communications. 499:299-306
Apoptosis plays a critical role in normal embryonic development and tissue homeostasis regulation. EndophilinA2 (EndoA2) is widely reported to regulate endocytosis. Additionally, EndoA2 has been demonstrated to be involved in tumor metastasis, neuror
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0fd3b70903e2df092495dc651b8337f
https://doi.org/10.1016/j.bbrc.2018.03.151
https://doi.org/10.1016/j.bbrc.2018.03.151
Publikováno v:
Circulation Research. 125
Vascular complications induced by diabetes constitute the principal cause of morbidity and mortality in diabetic patients. It’s reported that carvacrol (CAR) possess a wide range of biological activities. The effect of CAR on diabetes-induced vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15eb61301862638e9c756f2685f6c2fa
https://doi.org/10.1161/res.125.suppl_1.921
https://doi.org/10.1161/res.125.suppl_1.921
Autor:
Xiang Zhu, Xiao‑Ya Zhao, Ru‑Chao Jiang, Kai‑Feng Chen, Jian‑Dong Luo, Yuan Qin, Qing Xiao, Sheng‑Ying Chen, Ying‑Hua Liu, Xiu‑Hui Chen, Xiao-Ling Zhang
Publikováno v:
International Journal of Molecular Medicine
Damaged endothelial progenitor cells (EPCs) are associated with poor prognosis in diabetic myocardial infarction (DMI). Our previous studies revealed that an impaired Sonic hedgehog (Shh) pathway contributes to insufficient function in diabetic EPCs;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f90a42c2c355c95fbe806ece38b2ac
https://doi.org/10.3892/ijmm.2019.4277
https://doi.org/10.3892/ijmm.2019.4277
Autor:
Xin-Qiu-Yue, Wang, Zong-Tang, Xu, Gui-Ping, Zhang, Ning, Hou, Qin-Xing, Mo, Jie, Wei, Xin, Jiang, Yun, Liu, Jian-Dong, Luo
Publikováno v:
American journal of translational research. 11(8)
Decreased autophagy has been reported to contribute to the progression of cardiac hypertrophy. Our previous research has demonstrated that endophilin A2 (EndoA2) attenuates H(2)O(2)-induced cardiomyocyte apoptosis by strengthening autophagy. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::270b502aeda1b93e169a916a4bb4485a
https://pubmed.ncbi.nlm.nih.gov/31497222
https://pubmed.ncbi.nlm.nih.gov/31497222
Autor:
Yuan Qin, Qing Xiao, Gui‑Ping Zhang, Yan‑Hua He, Xiao-Ya Zhao, Jian‑Dong Luo, Ya Yang, Li‑Shan He
Publikováno v:
Experimental and Therapeutic Medicine
Our previous study demonstrated that an impaired sonic hedgehog (Shh) pathway contributed to cardiac dysfunction in type 1 diabetic mice with myocardial infarction (MI). The present study aimed to test the hypothesis that oxidative stress may contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bf94d9de646f2af19bcd97938d035a
http://europepmc.org/articles/PMC4665878
http://europepmc.org/articles/PMC4665878
Autor:
Kai-Fey Luo, Ning Hou, Quan Yi, Yinghua Liu, Wen-Liang Chen, Gen-Shui Zhang, Qin Xue, Xiaoen He, Jian-Dong Luo
Publikováno v:
Current Therapeutic Research. 73:174-185
BackgroundHuang-Lian-Jie-Du-Tang (HLJDT) is the classical traditional Chinese recipe for heat clearance and detoxification and is used in diabetic patients in the clinical practice of traditional Chinese medicine.ObjectiveThe aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6267ff6bedb1df6403dd049532bc2df4
https://doi.org/10.1016/j.curtheres.2012.09.002
https://doi.org/10.1016/j.curtheres.2012.09.002