Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Jian‐wei Chen"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-12 (2024)
Abstract The Eastern Pamir, distinguished with high altitude, extremely arid and cold climate, limited nutrients and sparse vegetation, is a unique ecological reservoir. Microbial communities play a central role in maintaining Eastern Pamir’s ecosy
Externí odkaz:
https://doaj.org/article/ea1cbc6354454869867b31be1d110333
Publikováno v:
Marine Drugs, Vol 22, Iss 9, p 409 (2024)
The actinomycete genus Rhodococcus is known for its diverse biosynthetic enzymes, with potential in pollutant degradation, chemical biocatalysis, and natural product exploration. Comparative genomics have analyzed the distribution patterns of non-rib
Externí odkaz:
https://doaj.org/article/440a5242cc524d04b21bab11cdb4f067
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundSARS-CoV-2 could trigger multiple immune responses, leading to several autoimmune diseases, including thyroid diseases. Many cases of thyroid diseases caused by COVID-19 infection have been reported. Here, we describe the disease developmen
Externí odkaz:
https://doaj.org/article/f086c30d270549b4a49fc5a53ff98422
Autor:
Bin Wei, Gang-Ao Hu, Zhen-Yi Zhou, Wen-Chao Yu, Ao-Qi Du, Cai-Ling Yang, Yan-Lei Yu, Jian-Wei Chen, Hua-Wei Zhang, Qihao Wu, Qi Xuan, Xue-Wei Xu, Hong Wang
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Background Marine prokaryotes are a rich source of novel bioactive secondary metabolites for drug discovery. Recent genome mining studies have revealed their great potential to bio-synthesize novel secondary metabolites. However, the exact b
Externí odkaz:
https://doaj.org/article/d3c55ca1485f45b18063970d3d75a896
Autor:
Tao-Shun Zhou, Bin Wei, Min He, Ya-Sheng Li, Ya-Kun Wang, Si-Jia Wang, Jian-Wei Chen, Hua-Wei Zhang, Zi-Ning Cui, Hong Wang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1736-1742 (2020)
Gut microbial β-glucuronidases have the ability to deconjugate glucuronides of some drugs, thus have been considered as an important drug target to alleviate the drug metabolites-induced gastrointestinal toxicity. In this study, thiazolidin-2-cyanam
Externí odkaz:
https://doaj.org/article/b4aa4ef45c4847c5a2685ad01ffb23f8
Autor:
Zhi Huang, Zhi-Kun Yang, Si-Qing Chen, Jian-Wei Chen, Xiao-Ze Bao, Xin-Yi Ye, Bin Wei, Zi-Ning Cui, Ya-Sheng Li, Hong Wang
Publikováno v:
Results in Chemistry, Vol 4, Iss , Pp 100391- (2022)
β-Carbolines are of great interest due to their broad spectrum of biochemical effects and pharmaceutical functions, especially antitumor activity. The N9 position at β-carboline is a modification site for important antitumor activity. Several pheny
Externí odkaz:
https://doaj.org/article/83db723aa3b74320a21545075b1f9d8e
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
IntroductionNeutrophil extracellular traps (NETs) act as a critical trigger of inflammation and coagulation. We hypothesized that NETs are associated with septic hypercoagulability.Materials and MethodsIn total, 82 patients admitted with sepsis in th
Externí odkaz:
https://doaj.org/article/080efb2f8b8c4046a246abc2d44f370a
Autor:
Bin Wei, Qi-Wu Zhong, Song-Ze Ke, Tao-Shun Zhou, Qiao-Li Xu, Si-Jia Wang, Jian-Wei Chen, Hua-Wei Zhang, Wei-Hua Jin, Hong Wang
Publikováno v:
Marine Drugs, Vol 18, Iss 9, p 444 (2020)
A low fasting blood glucose level is a common symptom in diabetes patients and can be induced by high-fat diet (HFD) feeding at an early stage, which may play important roles in the development of diabetes, but has received little attention. In this
Externí odkaz:
https://doaj.org/article/73b93d5e240146e2a1d42fa699bd1640
Autor:
Chuan-Kang Ting, Choun-Sea Lin, Ming-Tsai Chan, Jian-Wei Chen, Sheng-Yu Chuang, Yao-Ting Huang
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166721 (2016)
The genome of many species in the biosphere is a diploid consisting of paternal and maternal haplotypes. The differences between these two haplotypes range from single nucleotide polymorphisms (SNPs) to large-scale structural variations (SVs). Existi
Externí odkaz:
https://doaj.org/article/e78629e5cf2148c0839bfc9133a6ec3c
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115794 (2014)
BackgroundA number of factors, including gender, age, smoking habits, and occupational exposure, affect the levels of urinary cadmium. Few studies have considered these influences when calculating the benchmark dose (BMD) of cadmium. In the present s
Externí odkaz:
https://doaj.org/article/731902142fad446cbf24ac7d2eb90a2c