Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jian‐ge Chen"'
Publikováno v:
Orthopaedic Surgery, Vol 16, Iss 1, Pp 234-244 (2024)
Objective Closed reduction combined with external fixation is a frequently utilized approach for treating distal radial fractures in adults. Nonetheless, the potential for re‐displacement following external fixation remains. Analyzing the factors i
Externí odkaz:
https://doaj.org/article/24c13c527fdb4a9a80e8abc0e6fa78e7
Publikováno v:
Journal of Chromatography A. 917:63-73
This article presents a systematic approach to investigate, document, and eliminate pharmaceutical HPLC assay bias using experimental design. This is the first article to describe the application of experimental design in the area of assay bias. It i
Publikováno v:
AAPS PharmSciTech. 1:5-9
Publikováno v:
Electroanalysis. 11:331-336
Visible spectroscopy and the rotating ring-disk electrode were used to study Cu(II)-peptide complexation of 21 peptides including N-acylated and N-pyroglutamyl peptides. All of the investigated peptides formed a complex with copper ion, and those com
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 14:155-164
An electrochemical detection method was applied to the determination of the synthetic peptide TP9201 (Telios Pharmaceuticals). The method utilizes reversed-phase HPLC, followed by post-column formation of Cu(II)-peptide complexes to render peptides e
Autor:
Jian-Ge Chen, Stephen G. Weber
Publikováno v:
Analytical Chemistry. 67:3596-3604
We used a microbore reversed phase column for acetonitrile/0.1% aqueous TFA gradient elution separation of peptides with the detection of their copper complexes by electrochemical detection. The copper complexes are formed in a short (1 or 1.5 min) p
Publikováno v:
Journal of Chromatography A. 691:301-315
Post-column reaction of peptides with Cu(II) can be used for the electrochemical detection of peptides as their biuret complexes. Understanding of the behavior (sensitivity at the anode and cathode in the dual-series electrochemical detector) of the
Publikováno v:
Journal of the American Chemical Society. 115:7343-7350
A novel and sensitive method has been developed and evaluated for the study of carbamate formation equilibria of amino acids and peptides in aqueous solution. The method is based on reversed-phase liquid chromatography with cetyltrimethylammonium bro
Autor:
Jian-Ge Chen, Jian-Ge (James) Chen, Debbie A. Markovitz, Amy Y. Yang, Shelley R. Rabel, Josephine Pang, Olga Dolinsky, Lei-Shu Wu, Mark Alasandro
Publikováno v:
Pharmaceutical development and technology. 5(4)
The purpose of this paper was to investigate the degradation chemistry of a fluoropyridinyl drug candidate in capsule formulation and to optimize the formulation based on a proposed degradation mechanism. Small developmental batches of capsules were