Zobrazeno 1 - 10
of 517
pro vyhledávání: '"Jian‐Min Chen"'
Autor:
Min‐Jun Wang, Yuan‐Chen Wang, Emmanuelle Masson, Ya‐Hui Wang, Dong Yu, Yang‐Yang Qian, Xin‐Ying Tang, Shun‐Jiang Deng, Liang‐Hao Hu, Lei Wang, Li‐Juan Wang, Vinciane Rebours, David N. Cooper, Claude Férec, Zhao‐Shen Li, Jian‐Min Chen, Wen‐Bin Zou, Zhuan Liao
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Chronic pancreatitis (CP) is a complex disease with genetic and environmental factors at play. Through trio exome sequencing, a de novo SEC16A frameshift variant in a Chinese teenage CP patient is identified. Subsequent targeted next‐gener
Externí odkaz:
https://doaj.org/article/c5f4c65631754818979730d06240b965
Autor:
Jian Luo, Xiao-Bo Liu, Qian Yao, Yi Qu, Jin Yang, Ke Lin, Shi-Rong Pan, Tian-Yi Wang, Yun Dai, Huan-Yu Chen, Jian-Min Chen, Zheng Yang
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-16 (2024)
Abstract Background Studies has suggested that receiving social support improves the professional identity of health professional students. According to the two-way social support theory, social support includes receiving social support and giving so
Externí odkaz:
https://doaj.org/article/eb6e310bc41e4c7888ee3666340e186e
Autor:
Yuepeng Hu, Jian-Min Chen, Han Zuo, Na Pu, Guofu Zhang, Yichen Duan, Gang Li, Zhihui Tong, Weiqin Li, Baiqiang Li, Qi Yang
Publikováno v:
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Lipoprotein lipase (LPL) plays a crucial role in triglyceride hydrolysis. Rare biallelic variants in the LPL gene leading to complete or near-complete loss of function cause autosomal recessive familial chylomicronemia syndrome. H
Externí odkaz:
https://doaj.org/article/7eacbf00ac0f4b20924505722c98d8de
Autor:
Hao Wu, Jin-Huan Lin, Xin-Ying Tang, Gaëlle Marenne, Wen-Bin Zou, Sacha Schutz, Emmanuelle Masson, Emmanuelle Génin, Yann Fichou, Gerald Le Gac, Claude Férec, Zhuan Liao, Jian-Min Chen
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-23 (2024)
Abstract Background Single-nucleotide variants (SNVs) within gene coding sequences can significantly impact pre-mRNA splicing, bearing profound implications for pathogenic mechanisms and precision medicine. In this study, we aim to harness the well-e
Externí odkaz:
https://doaj.org/article/d02d19b436f74bb4b284a9c0563849d2
Autor:
Yuepeng Hu, Guofu Zhang, Qi Yang, Na Pu, Kaiwei Li, Baiqiang Li, David N. Cooper, Zhihui Tong, Weiqin Li, Jian-Min Chen
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-9 (2023)
Abstract Background Lipoprotein lipase (LPL) is the key enzyme responsible for the hydrolysis of triglycerides. Loss-of-function variants in the LPL gene are associated with hypertriglyceridemia (HTG) and HTG-related diseases. Unlike nonsense, frames
Externí odkaz:
https://doaj.org/article/92e5f75a086949e7a4a051b0ff16602f
Autor:
Guofu Zhang, Yuepeng Hu, Qi Yang, Na Pu, Gang Li, Jingzhu Zhang, Zhihui Tong, Emmanuelle Masson, David N. Cooper, Jian-Min Chen, Weiqin Li
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Background Lipoprotein lipase (LPL) is the rate-limiting enzyme for triglyceride hydrolysis. Homozygous or compound heterozygous LPL variants cause autosomal recessive familial chylomicronemia syndrome (FCS), whereas simple heterozygous LPL
Externí odkaz:
https://doaj.org/article/6e0b2acecd7045c7b7befd71c176c5b1
Autor:
Jian Luo, Xiao-Bo Liu, Qian Yao, Yi Qu, Jin Yang, Ke Lin, Shi-Rong Pan, Tian-Yi Wang, Yun Dai, Huan-Yu Chen, Jian-Min Chen, Zheng Yang
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7efc4efe76ac4dbfa967aced3be2554c
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Ischemic stroke (IS) is a serious neurological disease that largely results in long-term disability and death. Extensive evidence has indicated that the activation of inflammation and ferroptosis significantly contribute to the de
Externí odkaz:
https://doaj.org/article/86bde701b85649b4b91c7faeeb2073e8
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background In recent years, non-invasive brain stimulation (NIBS) has been used for motor function recovery. However, the effects of NIBS in populations with spinal cord injury (SCI) remain unclear. This study aims to conduct a meta-analysis
Externí odkaz:
https://doaj.org/article/b6584d69935140f7980075133f0e02e0
Autor:
Yuan-Chen Wang, Wen-Bin Zou, Da-Hai Tang, Lei Wang, Liang-Hao Hu, Yang-Yang Qian, David N. Cooper, Claude Férec, Zhao-Shen Li, Jian-Min Chen, Zhuan Liao
Publikováno v:
Gastro Hep Advances, Vol 2, Iss 2, Pp 186-195 (2023)
Background and Aims: Heavy alcohol consumption and genetic factors represent the 2 major etiologies of chronic pancreatitis (CP). However, little is so far known about the clinical features and genetic basis of light-to-moderate alcohol consumption-r
Externí odkaz:
https://doaj.org/article/37f13a2060944ab5bb6c73244fcce54d