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pro vyhledávání: '"Jian'er Lin"'
Autor:
Ngan T B Nguyen, Mariati, Jessna H. M. Yeo, Terry Nguyen-Khuong, Jian'er Lin, Shi Jie Tay, Yuansheng Yang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
Therapeutic antibodies are decorated with complex-type N-glycans that significantly affect their biodistribution and bioactivity. The N-glycan structures on antibodies are incompletely processed in wild-type CHO cells due to their limited glycosylati
Autor:
Shu Hui Neo, Yuansheng Yang, Jessna H. M. Yeo, Steven C. L. Ho, Tianhua Wang, Xuezhi Bi, Jian'er Lin, Sheng-Hao Chao, Wei Zhang
Publikováno v:
Biotechnology journal. 12(9)
Studies had shown the benefits of using furin-2A peptides for high monoclonal antibody (mAb) expression in mammalian cells. How signal peptides affect furin-2A mediated mAb secretion has yet to be investigated. The impact of signal peptides on mAb se