Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jiameng Dan"'
Publikováno v:
Cancer Biology & Medicine, Vol 20, Iss 8, Pp 545-552 (2023)
Externí odkaz:
https://doaj.org/article/4664501a56d7477fae089cfc8d588c9c
Autor:
Haisong Liu, Ronghui Li, Hsin-Kai Liao, Zheying Min, Chao Wang, Yang Yu, Lei Shi, Jiameng Dan, Alberto Hayek, Llanos Martinez Martinez, Estrella Nuñez Delicado, Juan Carlos Izpisua Belmonte
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Human pluripotent stem cell (hPSC) derived pancreatic beta cells are a promising and potentially limitless source for cell replacement therapy. Here the authors perform stage-wise chemical screening to develop an improved protocol for hPSC differenti
Externí odkaz:
https://doaj.org/article/e0538b6a302e489391b9de003c23bba8
Publikováno v:
Cells, Vol 11, Iss 3, p 456 (2022)
Proper telomere length is essential for indefinite self-renewal of embryonic stem (ES) cells and cancer cells. Telomerase-deficient late generation mouse ES cells and human ALT cancer cells are able to propagate for numerous passages, suggesting telo
Externí odkaz:
https://doaj.org/article/a8a782cc76594e9ea8fe3fe9fc504c21
Autor:
Nicolas Veland, Swanand Hardikar, Yi Zhong, Sitaram Gayatri, Jiameng Dan, Brian D. Strahl, Scott B. Rothbart, Mark T. Bedford, Taiping Chen
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3390-3397 (2017)
Summary: DNA methylation plays crucial roles in chromatin structure and gene expression. Aberrant DNA methylation patterns, including global hypomethylation and regional hypermethylation, are associated with cancer and implicated in oncogenic events.
Externí odkaz:
https://doaj.org/article/7f414f8837684284866b48335ef2ff51
Autor:
Jiameng Dan, Philippe Rousseau, Swanand Hardikar, Nicolas Veland, Jiemin Wong, Chantal Autexier, Taiping Chen
Publikováno v:
Cell Reports, Vol 20, Iss 8, Pp 1936-1949 (2017)
Proper telomere length is essential for embryonic stem cell (ESC) self-renewal and pluripotency. Mouse ESCs (mESCs) sporadically convert to a transient totipotent state similar to that of two-cell (2C) embryos to recover shortened telomeres. Zscan4,
Externí odkaz:
https://doaj.org/article/84580ee6e0174731a1a52e420b2b73fd
Autor:
Jiao Yang, Renpeng Guo, Hua Wang, Xiaoying Ye, Zhongcheng Zhou, Jiameng Dan, Haiying Wang, Peng Gong, Wei Deng, Yu Yin, ShiQing Mao, Lingbo Wang, Junjun Ding, Jinsong Li, David L. Keefe, Meelad M. Dawlaty, Jianlong Wang, GuoLiang Xu, Lin Liu
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1809-1821 (2016)
Ten-eleven translocation (Tet) family proteins convert 5-methylcytosine to 5-hydroxymethylcytosine. We show that mouse embryonic stem cells (ESCs) depleted of Tet1 and/or Tet2 by RNAi exhibit short telomeres and chromosomal instability, concomitant w
Externí odkaz:
https://doaj.org/article/583a8ae977d24f889c5b25d7fbbde2bb
Autor:
Jeesun Kim, Hongbo Zhao, Jiameng Dan, Soojin Kim, Swanand Hardikar, Debra Hollowell, Kevin Lin, Yue Lu, Yoko Takata, Jianjun Shen, Taiping Chen
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005970 (2016)
Oocyte meiotic progression and maternal-to-zygote transition are accompanied by dynamic epigenetic changes. The functional significance of these changes and the key epigenetic regulators involved are largely unknown. Here we show that Setdb1, a lysin
Externí odkaz:
https://doaj.org/article/46377a802a1345aab117ae38590d51ff
Publikováno v:
Biology Open, Vol 1, Iss 11, Pp 1118-1127 (2012)
Summary Lamin A is an inner nuclear membrane protein that maintains nuclear structure integrity, is involved in transcription, DNA damage response and genomic stability, and also links to cell differentiation, senescence, premature aging and associat
Externí odkaz:
https://doaj.org/article/2c4efdaf25364cd38231f6980a69444f
Autor:
Llanos Martinez Martinez, Zheying Min, Alberto Hayek, Haisong Liu, Estrella Nuñez Delicado, Lei Shi, Chao Wang, Ronghui Li, Juan Carlos Izpisua Belmonte, Jiameng Dan, Hsin-Kai Liao, Yang Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Human pluripotent stem cell (hPSC)-derived pancreatic β cells are an attractive cell source for treating diabetes. However, current derivation methods remain inefficient, heterogeneous, and cell line dependent. To address these issues, we first devi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a9b0c4686d3ddcc6cd05d75981bc5f
https://doaj.org/article/e0538b6a302e489391b9de003c23bba8
https://doaj.org/article/e0538b6a302e489391b9de003c23bba8
Autor:
Taiping Chen, Jiameng Dan
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783031114533
Advances in Experimental Medicine and Biology ISBN: 9783319436227
Adv Exp Med Biol
Advances in Experimental Medicine and Biology ISBN: 9783319436227
Adv Exp Med Biol
Cytosine methylation at the C5-position – generating 5-methylcytosine (5mC) – is a DNA modification found in many eukaryotic organisms, including fungi, plants, invertebrates and vertebrates, albeit its levels vary greatly in different organisms.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64406116ad9e4c3e6f6e5797bbccd81a
https://doi.org/10.1007/978-3-031-11454-0_5
https://doi.org/10.1007/978-3-031-11454-0_5
