Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jiamei Lian"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Externí odkaz:
https://doaj.org/article/2cc46a823fa44672a42fc2777a3d47e2
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1403 (2024)
Olanzapine is an atypical antipsychotic drug and a potent muscarinic M3 receptor (M3R) antagonist. Olanzapine has been reported to cause metabolic disorders, including dyslipidemia. Anaplastic lymphoma kinase (Alk), a tyrosine kinase receptor well kn
Externí odkaz:
https://doaj.org/article/bf2d34d9686b45b786fd94c77a0a6fff
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Introduction: Neuroinflammation in the central nervous system, particularly the prefrontal cortex (PFC), plays a role in the pathogenesis of schizophrenia, which has been found to be associated with maternal immune activation (MIA). Recent evidence s
Externí odkaz:
https://doaj.org/article/8437f91861a74a4eb3c22b3b391aa5ec
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 732 (2022)
The ventral tegmental area (VTA) in the ventral midbrain is the origin of the dopaminergic neurotransmission pathways. Although GABAA receptors and AKT-GSK3β signaling are involved in the pathophysiology of mental disorders and are modulated by anti
Externí odkaz:
https://doaj.org/article/795c5b6134f54c4f991f80fc0f37d791
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Chronic treatment with second-generation antipsychotic drugs (SGAs) has been associated with an increased risk of metabolic syndrome. To evaluate the longitudinal changes in glucose-lipid homeostasis after SGA use, we studied the time-depend
Externí odkaz:
https://doaj.org/article/d44ba3620fcd44e58ea44ad0872f6987
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132722 (2015)
Aripiprazole is a wide-used antipsychotic drug with therapeutic effects on both positive and negative symptoms of schizophrenia, and reduced side-effects. Although aripiprazole was developed as a dopamine D2 receptor (D2R) partial agonist, all other
Externí odkaz:
https://doaj.org/article/da260ef448f64882ba1281e79741ce64
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104160 (2014)
Olanzapine is the one of first line antipsychotic drug for schizophrenia and other serious mental illness. However, it is associated with troublesome metabolic side-effects, particularly body weight gain and obesity. The antagonistic affinity to hist
Externí odkaz:
https://doaj.org/article/fe95fcc676bc4917a86ca041fbd06363
Publikováno v:
BMC Anesthesiology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Patients who are recovering from general anesthesia commonly exhibit symptoms such as dry lips, throat irritation, and thirst, prompting a desire to drink water in the post-anesthesia care unit (PACU). In this study, we aimed to e
Externí odkaz:
https://doaj.org/article/4e0ae63b147f44bf8647b09a7cb0c5e6
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9143
As a partial histamine H1 receptor agonist and H3 antagonist, betahistine has been reported to partially prevent olanzapine-induced dyslipidemia and obesity through a combination therapy, although the underlying epigenetic mechanisms are still not kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b565de6ef8c2b256d212952fc4439f27
https://doi.org/10.3390/ijms24119143
https://doi.org/10.3390/ijms24119143
Publikováno v:
Pharmacology, biochemistry, and behavior. 219
Second generation antipsychotic drugs including aripiprazole, olanzapine and risperidone are prescribed increasingly (mostly off-label) to treat various mental disorders in children and adolescents. Early treatment with antipsychotics during this per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114eec45ac0a44894d2c5860653a9385
https://pubmed.ncbi.nlm.nih.gov/36029928
https://pubmed.ncbi.nlm.nih.gov/36029928