Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jialei Duan"'
Autor:
Samadrita Bhattacharyya, Rahul K. Kollipara, Gabriela Orquera-Tornakian, Sean Goetsch, Minzhe Zhang, Cameron Perry, Boxun Li, John M. Shelton, Minoti Bhakta, Jialei Duan, Yang Xie, Guanghua Xiao, Bret M. Evers, Gary C. Hon, Ralf Kittler, Nikhil V. Munshi
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Comprehensive cis-regulatory landscapes are essential for accurate enhancer prediction and disease variant mapping. Although cis-regulatory element (CRE) resources exist for most tissues and organs, many rare — yet functionally important — cell t
Externí odkaz:
https://doaj.org/article/46dde78eea664fca9e8ce2e867c261c0
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2570-2578.e5 (2019)
Summary: Single-cell screens enable high-throughput functional assessment of enhancers in their endogenous genomic context. However, the design of current studies limits their application to identifying the primary gene targets of enhancers. Here, we
Externí odkaz:
https://doaj.org/article/e41940ede607471781cc79668953c0e7
Autor:
Chuan Xia, Lichao Zhang, Cheng Zou, Yongqiang Gu, Jialei Duan, Guangyao Zhao, Jiajie Wu, Yue Liu, Xiaohua Fang, Lifeng Gao, Yuannian Jiao, Jiaqiang Sun, Yinghong Pan, Xu Liu, Jizeng Jia, Xiuying Kong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The male-sterilems2 mutant has facilitated commercial production of wheat for over 40 years. Here, Xia et al. map Ms2and describe how a retrotransposon insertion event in the regulatory element of an orphan gene is associated with expression in anthe
Externí odkaz:
https://doaj.org/article/52319968687d4103b3a90f328ac07187
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3486-3499.e6 (2019)
Summary: Ectopic expression of transcription factors (TFs) can reprogram cell state. However, because of the large combinatorial space of possible TF cocktails, it remains difficult to identify TFs that reprogram specific cell types. Here, we develop
Externí odkaz:
https://doaj.org/article/2805e13f0d1e46ccab417572d87d423c
Autor:
Samadrita Bhattacharyya, Jialei Duan, Ryan J. Vela, Minoti Bhakta, Pietro Bajona, Pradeep P.A. Mammen, Gary C. Hon, Nikhil V. Munshi
Publikováno v:
Circulation. 146:878-881
Publikováno v:
Journal of International Education and Development. 6:70-75
Autor:
Samadrita Bhattacharyya, Rahul K. Kollipara, Gabriela Orquera-Tornakian, Sean Goetsch, Minzhe Zhang, Cameron Perry, Boxun Li, John M. Shelton, Minoti Bhakta, Jialei Duan, Yang Xie, Guanghua Xiao, Bret M. Evers, Gary C. Hon, Ralf Kittler, Nikhil V. Munshi
Publikováno v:
The Journal of clinical investigation.
Comprehensive cis-regulatory landscapes are essential for accurate enhancer prediction and disease variant mapping. Although cis-regulatory element (CRE) resources exist for most tissues and organs, many rare - yet functionally important - cell types
Autor:
Leqian Yu, Toshihiko Ezashi, Yulei Wei, Jialei Duan, Deirdre Logsdon, Linfeng Zhan, Asrafun Nahar, Carlos A. Pinzon Arteaga, Lizhong Liu, Caitlen Stobbe, Mandy Katz-Jaffe, William B Schoolcraft, Lei Wang, Tao Tan, Gary C. Hon, Ye Yuan, Jun Wu
SUMMARYRecent advances in human blastoids generated from naïve pluripotent stem cells have opened a new avenue for modelling early human development and implantation. Despite the success, however, existing protocols have several limitations, e.g., t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef1a436e1a873e64ebd97ed5361d0966
https://doi.org/10.1101/2022.09.14.507946
https://doi.org/10.1101/2022.09.14.507946
Autor:
Masahiro Sakurai, Leqian Yu, Lei Wang, Yulei Wei, Gary C. Hon, Shuhua Zhao, Kunhua Wang, Jialei Duan, Jun Wu, Daniel A. Schmitz
Publikováno v:
Nature. 591:620-626
Limited access to embryos has hampered the study of human embryogenesis and disorders that occur during early pregnancy. Human pluripotent stem cells provide an alternative means to study human development in a dish1–7. Recent advances in partial e
Autor:
Jialei Duan, Gary C. Hon
Publikováno v:
Bioinformatics
Motivation Single cell RNA-Seq (scRNA-Seq) has broadened our understanding of cellular heterogeneity and provided valuable insights into cellular functions. Recent experimental strategies extend scRNA-Seq readouts to include additional features, incl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4667e9bb31098352422b827dc2ab6a6c
https://europepmc.org/articles/PMC9502162/
https://europepmc.org/articles/PMC9502162/