Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Jiajun, Dong"'
Autor:
Yu Wang, Huihuang Lin, Anqi Yang, Jiaming Huang, Weicong Ren, Jiajun Dong, Shaojie Wang, Wenxue Xu, Yu Pang, Jieming Qu, Jia Liu
Publikováno v:
View, Vol 5, Iss 3, Pp n/a-n/a (2024)
Abstract Mycobacterium tuberculosis (MTB) is the causal pathogen of tuberculosis (TB). Rapid and accurate detection of live MTB is important for transmission control and patient treatment. Here, we described a clustered regularly interspaced short pa
Externí odkaz:
https://doaj.org/article/b8008a30217e4c3c851f574b457f4054
Autor:
Yuchen Shang, Mingguang Yao, Zhaodong Liu, Rong Fu, Longbiao Yan, Long Yang, Zhongyin Zhang, Jiajun Dong, Chunguang Zhai, Xuyuan Hou, Liting Fei, GuanJie Zhang, Jianfeng Ji, Jie Zhu, He Lin, Bertil Sundqvist, Bingbing Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract As an advanced amorphous material, sp 3 amorphous carbon exhibits exceptional mechanical, thermal and optical properties, but it cannot be synthesized by using traditional processes such as fast cooling liquid carbon and an efficient strateg
Externí odkaz:
https://doaj.org/article/4dbce326c4234c52bb82a05854cf5318
Autor:
Yilong Peng, Zhengyuan Xie, Shaoai Chen, Yi Wu, Jiajun Dong, Jinhong Li, Jinlang He, Xiaolei Chen, Hongzhi Gao
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The purpose of this study was to explore the applicability of application effect of head-mounted mixed reality (MR) equipment combined with a three-dimensional (3D) printed model in neurosurgical ventricular and haematoma puncture
Externí odkaz:
https://doaj.org/article/0dd7fb7677bd4849b3e75bbac80b93d9
Autor:
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D. Huntington, Jeffrey J. Babon, Nadia J. Kershaw, Zhong-Yin Zhang, Jonathan B. Baell, Florian Wiede, Tony Tiganis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-27 (2023)
Abstract The inhibition of protein tyrosine phosphatases 1B (PTP1B) and N2 (PTPN2) has emerged as an exciting approach for bolstering T cell anti-tumor immunity. ABBV-CLS-484 is a PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. Here we hav
Externí odkaz:
https://doaj.org/article/0cb5e14e733040fe85a8642c25963be7
Autor:
Xiaozhao Wang, Cai Yao, Xudong Yao, Junxin Lin, Rui Li, Kun Huang, Weiming Lin, Xiaojun Long, Chao Dai, Jiajun Dong, Xuegong Yu, Wenwen Huang, Wenjian Weng, Qi Wang, Hongwei Ouyang, Kui Cheng
Publikováno v:
Bioactive Materials, Vol 22, Iss , Pp 168-179 (2023)
Dynamic regulation of cell-extracellular matrix (ECM)-material interactions is crucial for various biomedical applications. In this study, a light-activated molecular switch for the modulation of cell attachment/detachment behaviors was established o
Externí odkaz:
https://doaj.org/article/ff4c723049884f81b9bdd6346fcbac6d
Autor:
Cynthia D. Jesudason, Emily R. Mason, Shaoyou Chu, Adrian L. Oblak, June Javens‐Wolfe, Mustapha Moussaif, Greg Durst, Philip Hipskind, Daniel E. Beck, Jiajun Dong, Ovini Amarasinghe, Zhong‐Yin Zhang, Adam K. Hamdani, Kratika Singhal, Andrew D. Mesecar, Sarah Souza, Marlene Jacobson, Jerry Di Salvo, Disha M. Soni, Murugesh Kandasamy, Andrea R. Masters, Sara K Quinney, Suzanne Doolen, Hasi Huhe, Stacey J. Sukoff Rizzo, Bruce T. Lamb, Alan D. Palkowitz, Timothy I. Richardson
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 9, Iss 4, Pp n/a-n/a (2023)
Abstract INTRODUCTION The risk of developing Alzheimer's disease is associated with genes involved in microglial function. Inositol polyphosphate‐5‐phosphatase (INPP5D), which encodes Src homology 2 (SH2) domain–containing inositol polyphosphat
Externí odkaz:
https://doaj.org/article/4d6f6a10135b4cdbb5e5fc4dd51947a7
Autor:
Jiajun Dong, Shengnan Wang, Haoqun Xie, Yanhao Mou, Hao Zhu, Yilong Peng, Jianxin Xi, Minggu Zhong, Zhengyuan Xie, Zongyuan Jiang, Kang Wang, Hongyu Chen, Wenzhuo Yang, Mingqin Zhu, Yufeng Wen, Yi Wu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundAs a result of the COVID-19 pandemic, patients with glioblastoma (GBM) are considered a highly vulnerable population. Despite this, the extent of the causative relationship between GBM and COVID-19 infection is uncertain.MethodsGenetic inst
Externí odkaz:
https://doaj.org/article/1020220c399042849e19714f7637beff
Autor:
Jinmin Miao, Yunpeng Bai, Yiming Miao, Zihan Qu, Jiajun Dong, Ruo-Yu Zhang, Devesh Aggarwal, Brenson A. Jassim, Quyen Nguyen, Zhong-Yin Zhang
Publikováno v:
Molecules, Vol 28, Iss 19, p 6947 (2023)
Src homology 2 domain-containing phosphatase 2 (SHP2) is an attractive target for cancer therapy due to its multifaceted roles in both tumor and immune cells. Herein, we designed and synthesized a novel series of proteolysis targeting chimeras (PROTA
Externí odkaz:
https://doaj.org/article/db5fd6dcfae1472097563161c7abdfec
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Prolactinoma is the major cause of hyperprolactinemia, and dopamine agonists (DAs) are generally the first-line treatment for them. Several studies have reviewed the recurrent rate of hyperprolactinemia after DAs withdrawal. Howev
Externí odkaz:
https://doaj.org/article/017de2a0a1a64c9aa4461a58e0795625
Autor:
Chunguang Zhai, Xiu Yin, Shifeng Niu, Mingguang Yao, Shuhe Hu, Jiajun Dong, Yuchen Shang, Zhigang Wang, Quanjun Li, Bertil Sundqvist, Bingbing Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The design of piezochromic luminescent materials with desirable stimuliresponsive properties remains challenging. Here, the authors report the insertion of a non-emissive molecule into a donor and acceptor binary cocrystal and realize desirable piezo
Externí odkaz:
https://doaj.org/article/a32241e590fe4bfba895ef52e98cb618