Výsledky vyhledávání - "Jiajing Shan"

Akademický článek

A key role of miR-132-5p in the prefrontal cortex for persistent prophylactic actions of (R)-ketamine in mice

Autor: Li Ma, Long Wang, Lijia Chang, Jiajing Shan, Youge Qu, Xingming Wang, Xiayun Wan, Yuko Fujita, Kenji Hashimoto

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract (R,S)-ketamine is known to elicit persistent prophylactic effects in rodent models of depression. However, the precise molecular mechanisms underlying its action remain elusive. Using RNA-sequencing analysis, we searched for novel molecular

Externí odkaz: https://doaj.org/article/df5f5097b6214dbdbd5dcd4d24b0004a

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Akademický článek

Regulatory T cell expansion promotes white matter repair after stroke

Autor: Chunling Yuan, Ligen Shi, Zeyu Sun, Fei Xu, Chujun Wang, Jiajing Shan, T. Kevin Hitchens, Lesley M. Foley, Qing Ye, Jun Chen, Dandan Sun, Xiaoming Hu

Publikováno v: Neurobiology of Disease, Vol 179, Iss , Pp 106063- (2023)

Recent research highlights the function of regulatory T cells (Tregs) in white matter integrity in CNS diseases. Approaches that expand the number of Tregs have been utilized to improve stroke recovery. However, it remains unclear if Treg augmentatio

Externí odkaz: https://doaj.org/article/922a68ebcaf044a1a06d40a16b2bac7b

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Akademický článek

Nuclear factor of activated T cells 4 in the prefrontal cortex is required for prophylactic actions of (R)-ketamine

Autor: Li Ma, Jiancheng Zhang, Yuko Fujita, Youge Qu, Jiajing Shan, Xiayun Wan, Xingming Wang, Tamaki Ishima, Kenta Kobayashi, Long Wang, Kenji Hashimoto

Publikováno v: Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract (R, S)-ketamine has prophylactic antidepressant-like effects in rodents; however, the precise molecular mechanisms underlying its action remain unknown. Using RNA-sequencing analysis, we searched novel molecular target(s) that contribute to

Externí odkaz: https://doaj.org/article/f32c469a36c84859a13c5db52a93723a

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Akademický článek

Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain

Autor: Xingming Wang, Akifumi Eguchi, Yong Yang, Lijia Chang, Xiayun Wan, Jiajing Shan, Youge Qu, Li Ma, Chisato Mori, Jianjun Yang, Kenji Hashimoto

Publikováno v: Neurobiology of Disease, Vol 176, Iss , Pp 105951- (2023)

Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. Dietary intake of cuprizone (CPZ) produces demyelination resembling that of patients with MS. Given the role of the vagus nerve in gut–microbi

Externí odkaz: https://doaj.org/article/433f4dbddf26483f83aae9dde784c582

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Akademický článek

Corrigendum to '(R)-ketamine ameliorates demyelination and facilitates remyelination in cuprizone-treated mice: A role of gut–microbiota–brain axis' [Neurobiol Dis. 165 (2022):105635.]

Autor: Xingming Wang, Lijia Chang, Xiayun Wan, Yunfei Tan, Youge Qu, Jiajing Shan, Yong Yang, Li Ma, Kenji Hashimoto

Publikováno v: Neurobiology of Disease, Vol 170, Iss , Pp 105779- (2022)

Externí odkaz: https://doaj.org/article/c38eda3c9e1d49fdba3db1c108efeeef

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Akademický článek

(R)-ketamine ameliorates demyelination and facilitates remyelination in cuprizone-treated mice: A role of gut–microbiota–brain axis

Autor: Xingming Wang, Lijia Chang, Xiayun Wan, Yunfei Tan, Youge Qu, Jiajing Shan, Yong Yang, Li Ma, Kenji Hashimoto

Publikováno v: Neurobiology of Disease, Vol 165, Iss , Pp 105635- (2022)

Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. We recently reported that the new antidepressant (R)-ketamine could ameliorate the disease progression in experimental autoimmune encephalomyeli

Externí odkaz: https://doaj.org/article/468c6c555f52459889da29ed2b1ed592

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