Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Jiahua JIANG"'
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e90024 (2014)
Members of the EAG K(+) channel superfamily (EAG/Kv10.x, ERG/Kv11.x, ELK/Kv12.x subfamilies) are expressed in many cells and tissues. In particular, two prototypes, EAG1/Kv10.1/KCNH1 and ERG1/Kv11.1/KCNH2 contribute to both normal and pathological fu
Externí odkaz:
https://doaj.org/article/7093a1f01e3e4f7c907a579ecce07563
Autor:
Jiahua Jiang, Anita Thyagarajan-Sahu, Viktor Krchňák, Andrej Jedinak, George E Sandusky, Daniel Sliva
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34283 (2012)
BACKGROUND: We have recently synthesized novel N-alkylated amino acid-derived hydroxamate, 2-[Benzyl-(2-nitro-benzenesulfonyl)-amino]-N-hydroxy-3-methyl-N-propyl-butyramide (NAHA). Here, we evaluate the anticancer activity of NAHA against highly inva
Externí odkaz:
https://doaj.org/article/98f260e1d35e41fdb1a83be99df7b5f9
Autor:
Daniel Sliva, Jagadish Loganathan, Jiahua Jiang, Andrej Jedinak, John G Lamb, Colin Terry, Lee Ann Baldridge, Jiri Adamec, George E Sandusky, Shailesh Dudhgaonkar
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47873 (2012)
Epidemiological studies suggest that mushroom intake is inversely correlated with gastric, gastrointestinal and breast cancers. We have recently demonstrated anticancer and anti-inflammatory activity of triterpene extract isolated from mushroom Ganod
Externí odkaz:
https://doaj.org/article/f64edd40747d47a283f75487da08386f
Publikováno v:
SIAM Journal on Scientific Computing; 2024, Vol. 46 Issue 2, pS97-S119, 23p
Reduction of projection views in X-ray computed tomography (CT) can protect patients from over exposure to ionizing radiation, thus is highly attractive for clinical applications. However, image reconstruction for sparse-view CT which aims to produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7c21064cb480f33a9b22d0054299f58
https://doi.org/10.1101/2023.02.24.23286409
https://doi.org/10.1101/2023.02.24.23286409
Publikováno v:
Third International Symposium on Computer Engineering and Intelligent Communications (ISCEIC 2022).
Publikováno v:
Journal of Scientific Computing. 91
Dimension reduction is analytical methods for reconstructing high-order tensors that the intrinsic rank of these tensor data is relatively much smaller than the dimension of the ambient measurement space. Typically, this is the case for most real wor
Autor:
Beibei Fu, He Kaijie, Chang Bai, Lei Zhang, Liang Jindong, Xu Jianyan, Lianshan Zhang, Yan Li, Ye Xin, Mi Tang, Zhebin Zhang, Weikang Tao, Jiahua Jiang
Publikováno v:
Molecular Cancer Therapeutics. 18:1104-1114
Although inhibiting EGFR-mediated signaling proved to be effective in treating certain types of cancers, a quickly evolved mechanism that either restores the EGFR signaling or activates an alternative pathway for driving the proliferation and surviva
Publikováno v:
Computers & Mathematics with Applications. 77:1963-1979
The Reduced Basis Method (RBM) is a rigorous model reduction approach for solving parametrized partial differential equations. It identifies a low-dimensional subspace for approximation of the parametric solution manifold that is embedded in high-dim
Autor:
Yang Changyong, Haoyu Fu, Lei Wang, Yun Li, Liguang Lou, Mingzhao Gao, Li Fu, Xubin Bao, Jiahua Jiang, Chengying Xie
Publikováno v:
Cancer Science
Poly(ADP-ribose) polymerase (PARP) enzymes play an important role in repairing DNA damage and maintaining genomic stability. Olaparib, the first-in-class PARP inhibitor, has shown remarkable clinical benefits in the treatment of BRCA-mutated ovarian