Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jiahe Mao"'
Autor:
Yang Miao, Yue Yang, Xiaohe Li, Lingxin Meng, Jiahe Mao, Jianwei Zhang, Jingjing Gao, Cheng Yang, Xiaoting Gu, Honggang Zhou, Yanping Zhang
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e20914- (2023)
Idiopathic pulmonary fibrosis (IPF) is an incurable chronic progressive disease with a low survival rate and ineffective therapeutic options. We examined the effects of imrecoxib, a nonsteroidal anti-inflammatory drug, on experimental pulmonary fibro
Externí odkaz:
https://doaj.org/article/9080f6b7336144d8b451a0406ed39bd0
Autor:
Xiaohe Li, Zhun Bi, Shuaishuai Liu, Shaoyan Gao, Yunyao Cui, Kai Huang, Mengying Huang, Jiahe Mao, Lixin Li, Jingjing Gao, Tao Sun, Honggang Zhou, Cheng Yang
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Idiopathic pulmonary fibrosis (IPF) is a progressive and usually fatal lung disease that is characterized by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible distortion of the lung’s architecture and the fo
Externí odkaz:
https://doaj.org/article/c998dab2fd3c41d4b3c152d13fc2bf08
Autor:
Jiahe Mao, Cheng Yang, Xiaohe Li, Min Hou, Xiang Liu, Junya Peng, Honggang Zhou, Yunyun Zhou, Guang Yang, Yuting Cao, Qi Min, Shuanglin Qin, Qiuyan Jiang, Sheng Cao, Maodun Xie, Yuyu Yang, Gang Lin, Yujiao Wei, Yang Song, Xinhua Liu, Cheng Lu
Publikováno v:
European journal of medicinal chemistry. 203
Idiopathic pulmonary fibrosis (IPF) and acute lung injury (ALI) are considered two severe public health issues, attributed to malfunctions of neutrophils. They can cause chronic inflammation and have association with subsequent tissue damages. There
Autor:
Jiahe Mao, Shuaishuai Liu, Chengcheng Su, Zhun Bi, Yujiao Wei, Sheng Pengzhen, Lin Zhao, Luqing Wei, Qi Min, Tao Sun, Shuangwei Liu, Kai Huang, Ning Liu, Cheng Lu, Honggang Zhou, Shaoyan Gao, Xiaohe Li, Guang Yang, Xinhua Liu, Shengxiang Miao, Wen Ning, Cheng Yang, Mengying Huang, Shuanglin Qin, Tongtong Liu, Ting Xiao
Publikováno v:
European Journal of Medicinal Chemistry. 157:229-247
In this study, anti-IPF lead compounds 42 and 44, derived from natural sesquiterpene lactones Isoalantolactone and alantolactone, were discovered by screening from a high-throughput TGF-β1 reporter luciferase assay. Notably, they could reduce the my