Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Jiagen Wen"'
Autor:
Nannan Ma, Hao Lu, Ning Li, Weijian Ni, Wenbo Zhang, Qiang Liu, Wenzheng Wu, Shichao Xia, Jiagen Wen, Tao Zhang
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-17 (2024)
Abstract In clinical practice, renal ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI), often leading to acute renal failure or end-stage renal disease (ESRD). The current understanding of renal IRI mechanisms remains u
Externí odkaz:
https://doaj.org/article/d84975ef3db646f9ac92e7c1c3678181
Autor:
Tingni Wu, Wenxian Ma, Weili Lu, Zhuofan Huangshen, Shiqing Chen, Qin Yang, Chao Li, Zeng Li, Ning Li, Xiaowen Feng, Li Li, Yu Miao, Jianan Wang, Xueqi Liu, Yuting Cai, Yuan He, Xiaoyan He, Jun Li, Ren Zhao, Jiagen Wen
Publikováno v:
Heliyon, Vol 9, Iss 11, Pp e21231- (2023)
Cisplatin is a chemotherapeutant widely used in treating solid tumors, with the common side effect of acute kidney injury (AKI). Developing effective useful agent for preventing or treating cisplatin-induced AKI is of great importance. In this study,
Externí odkaz:
https://doaj.org/article/e0c28fc60af840d68f4dc5f340971cf0
Autor:
Jiarong Wang, Wei Jiang, Jiao Xin, Weiju Xue, Congjian Shi, Jiagen Wen, Yan Huang, Chengmu Hu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Non-alcoholic fatty liver disease (NAFLD) is an independent risk factor for acute liver injury caused by overuse of acetaminophen (APAP). Caveolin-1 (CAV1), a regulator of hepatic energy metabolism and oxidative stress, was found to have a protective
Externí odkaz:
https://doaj.org/article/b60e040632ae468f8be1355b3b4b83fe
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 1, Pp 37-41 (2019)
Metformin is the most widely used drug among type 2 diabetes mellitus patients. However, drug interaction on metformin will influence its glucose-lowering effect or increase its side effect of lactic acidosis. In this study, a randomized, two-stage,
Externí odkaz:
https://doaj.org/article/01fce6a5195e41c29a4b71bcf47efc87
Autor:
Guojing Liu, Jiagen Wen, Dong Guo, Zhenmin Wang, Xiaolei Hu, Jie Tang, Zhaoqian Liu, Honghao Zhou, Wei Zhang
Publikováno v:
Journal of Pharmacological Sciences, Vol 132, Iss 4, Pp 244-248 (2016)
The aim was to investigate the role of rabeprazole on the pharmacokinetics (PK) and pharmacodynamics (PD) of metformin. The in vitro inhibition assays on metformin transport were carried out and showed that the half maximal inhibitory concentration (
Externí odkaz:
https://doaj.org/article/4adadfcc14484086bcdea43b1d674368
Autor:
Fazhong He, Jianquan Luo, Zhitao Zhang, Zhiying Luo, Lan Fan, Yijing He, Jiagen Wen, Dingilang Zhu, Jinping Gao, Yan Wang, Yuesheng Qian, Honghao Zhou, Xiaoping Chen, Wei Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0121483 (2015)
OBJECTIVE:Regulators of G-protein signaling protein 2 (RGS2) play an irreplaceable role in the control of normal blood pressure (BP). One RGS2 (-391, C>G) genetic variation markedly changes its mRNA expression levels. This study explored the relation
Externí odkaz:
https://doaj.org/article/7afdc020e1604218a650d5d0853171db
Autor:
Dongdong Fu, Shuai Wu, Xiangfu Jiang, Tingyu You, Yu Li, Jiao Xin, Xiaowen Feng, Jiagen Wen, Yan Huang, Chengmu Hu
Publikováno v:
Free Radical Biology and Medicine. 195:245-257
Acetaminophen (APAP) is one of the most widely used drugs in the world. The literature shows that excessive or long-term use of APAP can lead to increased cardiovascular dysfunction. An acute increase in angiotensin Ⅱ (Ang Ⅱ) caused by APAP use i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a2f2d3889b0daae1042d5a6ba2ddd5
https://doi.org/10.1016/j.freeradbiomed.2022.12.095
https://doi.org/10.1016/j.freeradbiomed.2022.12.095
Autor:
Ling Jiang, Xueqi Liu, Xueru Hu, Li Gao, Hanxu Zeng, Xian Wang, Yuebo Huang, Wei Zhu, Jianan Wang, Jiagen Wen, Xiaoming Meng, Yonggui Wu
Publikováno v:
Molecular Therapy. 30:1721-1740
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8020b268e6720b6ef2757bed19e9bd47
https://doi.org/10.1016/j.ymthe.2022.01.002
https://doi.org/10.1016/j.ymthe.2022.01.002
Autor:
Jinfang Ge, Maozong Zhu, Jiagen Wen, Fanrong Wu, Weili Lu, Xiaoming Meng, Xuefeng Xie, Feihu Chen
We investigated the effect of scientific practice on the learning outcome in course “Research and Development of New Drugs” via analyzing the performance of 232 bachelor of clinic pharmacy degree (BCPharm) undergraduates. The results showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::042dd60ab9fc66f9a94a6ace15780c4d
https://doi.org/10.21203/rs.3.rs-2205398/v1
https://doi.org/10.21203/rs.3.rs-2205398/v1
Autor:
Jiao Xin, Tingyu You, Xiangfu Jiang, Dongdong Fu, Jiarong Wang, Wei Jiang, Xiaowen Feng, Jiagen Wen, Yan Huang, Chengmu Hu
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7587
Acetaminophen (APAP) is a widely used antipyretic analgesic which can lead to acute liver failure after overdoses. Chronic alcoholic fatty liver disease (AFLD) appears to enhance the risk and severity of APAP-induced liver injury, and the level of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937f1b346ba6a4d33fa384da1b6adea5
https://pubmed.ncbi.nlm.nih.gov/35886933
https://pubmed.ncbi.nlm.nih.gov/35886933