Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jiafu Sun"'
Autor:
Ang Gao, Tonghua Sun, Gui Ma, Jiangran Cao, Qingxia Hu, Ling Chen, Yanxin Wang, Qianying Wang, Jiafu Sun, Rui Wu, Qiao Wu, Jiaxi Zhou, Lin Liu, Junjie Hu, Jin-Tang Dong, Zhengmao Zhu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Tamoxifen resistance is a major problem in the treatment of ERa positive breast cancer. Here, the authors show that LEM4 confers tamoxifen resistance by activating the cyclin D-CDK4/6-Rb axis and ERa signaling in endocrine-resistant breast cancer.
Externí odkaz:
https://doaj.org/article/7ff9424b6d604decaed08aa4fac77058
Background Diabetic retinopathy (DR), a diabetic vascular complication, is prone to developing into blindness. Ginsenoside Rg1 (GRg1), a major saponin in ginseng, exerts high anti-apoptotic activity. Methods This study aimed to explore the protective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecaa0aacf76c987b389fca5679d84002
https://europepmc.org/articles/PMC7154486/
https://europepmc.org/articles/PMC7154486/
Autor:
Ping Zhou, Xiaobo Sun, Weijie Xie, Tianyuan Ye, Mengren Zhang, Jiafu Sun, Fengwei Nan, Xi Dong, Guibo Sun, Xiao Sun
Publikováno v:
Molecular and cellular probes. 48
Diabetic encephalopathy is a severe diabetic complication characterized by cognitive dysfunction and neuropsychiatric disability. Methylglyoxal (MGO), a highly reactive metabolite of hyperglycemia, serves as a major precursor of advanced glycation en
Publikováno v:
Cellular and molecular life sciences : CMLS. 77(4)
Endocrine therapy represents a mainstay adjuvant treatment of estrogen receptor-positive (ER+) breast cancer in clinical practice with an overall survival (OS) benefit. However, the emergence of resistance is inevitable over time and is present in on
Publikováno v:
Fuel. 292:120371
To understand the plastic layer properties, which directly impact coke quality during the coking process, the plastic layer characteristics formed by seventeen kinds of coking coals were analyzed using a penetrometer equipped on a thermogravimetry–
Publikováno v:
Fuel. 182:879-885
The cokes with low reactivity index (CRI) and high coke strength after reaction (CSR) are generally regarded as good quality and acceptable for blast furnace (BF) operators. However, the cokes with greatly varied CRI and CSR can also be used in large
Publikováno v:
Fuel. 278:118225
The mass transfer process of coke solution loss reaction (Ccoke + CO2 = 2CO) was rather complex due to coke porous structure and non-equimolar diffusion. However, non-equimolar diffusion in the external and internal diffusion process was often neglec
Publikováno v:
Fuel. 263:116694
To provide a more accurate reference for coke quality evaluation, and to achieve the benefits of coking-coal resource use and energy conservation, a coke solution-loss degradation model was developed by combining non-equimolar diffusion, the parallel
Autor:
Junjie Hu, Jiangran Cao, Rui Wu, Qingxia Hu, Gui Ma, Jin-Tang Dong, Lin Liu, Qianying Wang, Ang Gao, Jiaxi Zhou, Qiao Wu, Jiafu Sun, Yanxin Wang, Zhengmao Zhu, Ling Chen, Tonghua Sun
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
The elucidation of molecular events that confer tamoxifen resistance to estrogen receptor α (ER) positive breast cancer is of major scientific and therapeutic importance. Here, we report that LEM4 overexpression renders ER+ breast cancer cells resis
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