SARS-CoV-2 Antibody Semi-Quantitative Levels Is Important In The Management Of COVID-19 Vaccinations In Immunodeficiency Disorder Patients

Autor: Joseph Chiao, Lili Wan, J. Joanna Yu, Shaobin Hou, Zhu Qian, Jing Yu, Jiafang Sun, Abby Sun, Alex Chi, Rose Tran, Kusuman Joseph, Dustin Battad, H. Henry Li

Publikováno v: Journal of Allergy and Clinical Immunology. 151:AB26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c4c19fbea4af1608c887f7b89bf023a
https://doi.org/10.1016/j.jaci.2022.12.083

Inhibiting DDX3X triggers tumor-intrinsic type I interferon response and enhances anti-tumor immunity

Autor: John L. Casey, Min Soon Cho, Yifan Sun, Jiafang Sun, Hyeongjwa Choi, Jeffrey A. Toretsky, Cecil Han, Juntae Kwon

Accumulating evidence has shown that cellular double-stranded RNAs (dsRNAs) induce antiviral innate immune responses in human normal and malignant cancer cells. However, it is not fully understood how endogenous ‘self’ dsRNA homeostasis is regula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8aa4a52706bb9a189e63372790ee45
https://doi.org/10.1101/2020.09.09.289587

Cutting Edge: Expression of IRF8 in Gastric Epithelial Cells Confers Protective Innate Immunity against Helicobacter pylori Infection

Autor: Chengfu Xu, Warren J. Leonard, Alexander L. Kovalchuk, Yin Zhu, Jiafang Sun, Peng Li, Nonghua Lv, Sadia Abbasi, Hongsheng Wang, Wei Liao, Yan Sun, Herbert C. Morse, Ming Yan, Jungsoo Joo

Publikováno v: The Journal of Immunology. 196:1999-2003

IFN regulatory factor 8 (IRF8) is expressed in many types of blood cells and plays critical roles in cellular differentiation and function. However, the role of IRF8 in nonhematopoietic systems remains poorly understood. In this study, we provide evi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f56ff16cbbc5d46563365febce3633b
https://doi.org/10.4049/jimmunol.1500766

Transcription factors IRF8 and PU.1 are required for follicular B cell development and BCL6-driven germinal center responses.

Autor: Hongsheng Wang, Shweta Jain, Peng Li, Jian-Xin Lin, Jangsuk Oh, Chenfeng Qi, Yuanyuan Gao, Jiafang Sun, Tomomi Sakai, Naghashfar, Zohreh, Abbasi, Sadia, Kovalchuk, Alexander L., Bolland, Silvia, Nutt, Stephen L., Leonard, Warren J., Morse III, Herbert C.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America; 5/7/2019, Vol. 116 Issue 19, p9511-9520, 10p

Characterization of ARF-BP1/HUWE1 Interactions with CTCF, MYC, ARF and p53 in MYC-Driven B Cell Neoplasms

Autor: Yongsoo Kim, Delin Chen, Ziedulla Abdullaev, Wei Gu, Alexander L. Kovalchuk, Jiafang Sun, Herbert C. Morse, Shao Xiang, William C. Cho, Siegfried Janz, Ted A. Torrey, Chen-Feng Qi

Publikováno v: International Journal of Molecular Sciences; Volume 13; Issue 5; Pages: 6204-6219
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 13, Iss 5, Pp 6204-6219 (2012)

Transcriptional activation of MYC is a hallmark of many B cell lineage neoplasms. MYC provides a constitutive proliferative signal but can also initiate ARF-dependent activation of p53 and apoptosis. The E3 ubiquitin ligase, ARF-BP1, encoded by HUWE1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c37997b21274b199a4565bd685a9a7