Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jiaen Deng"'
Autor:
Sarah T.K. Sin, Jiaen Deng, Lu Ji, Masashi Yukawa, Rebecca W.Y. Chan, Stefano Volpi, Augusto Vaglio, Paride Fenaroli, Paola Bocca, Suk Hang Cheng, Danny K.L. Wong, Kathy O. Lui, Peiyong Jiang, K.C. Allen Chan, Rossa W.K. Chiu, Y.M. Dennis Lo
Publikováno v:
JCI Insight, Vol 7, Iss 8 (2022)
Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear DNA has recently gained increasing research interest, with possible clinical applications as a class of biomarkers. In this study, we aimed to explore the rel
Externí odkaz:
https://doaj.org/article/bab172c80be04919b1e79aa0bf7c7aa8
Autor:
Deke Jiang, Jiaen Deng, Changzheng Dong, Xiaopin Ma, Qianyi Xiao, Bin Zhou, Chou Yang, Lin Wei, Carly Conran, S. Lilly Zheng, Irene Oi-lin Ng, Long Yu, Jianfeng Xu, Pak C. Sham, Xiaolong Qi, Jinlin Hou, Yuan Ji, Guangwen Cao, Miaoxin Li
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Recent genome-wide association studies (GWASs) have suggested several susceptibility loci of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) by statistical analysis at individual single-nucleotide polymorphisms (SNP
Externí odkaz:
https://doaj.org/article/db4e218ce7ce4ad88f22e3d6e781bbcb
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69719 (2013)
MicroRNAs (miRNAs) are a group of small non-coding RNAs that play important regulatory roles at the post-transcriptional level. Although several computational methods have been developed to compare miRNAs, it is still a challenging and a badly needed
Externí odkaz:
https://doaj.org/article/d5ce49bbc2e44c58aaf2a5dc8248eaf4
Autor:
Stephanie C Y Yu, Jiaen Deng, Rong Qiao, Suk Hang Cheng, Wenlei Peng, So Ling Lau, L Y Lois Choy, Tak Y Leung, John Wong, Vincent Wai-Sun Wong, Grace L H Wong, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Y M Dennis Lo
Publikováno v:
Clinical Chemistry. 69:168-179
Background Recent studies using single molecule, real-time (SMRT) sequencing revealed a substantial population of analyzable long cell-free DNA (cfDNA) in plasma. Potential clinical utilities of such long cfDNA in pregnancy and cancer have been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b9a2f27dc66f5426bbe570a279561b
https://doi.org/10.1093/clinchem/hvac180
https://doi.org/10.1093/clinchem/hvac180
Autor:
Macy M. S. Heung, Caitlyn So Ling Lau, Suk Hang Cheng, Sarah T K Sin, Peiyong Jiang, Y.M. Dennis Lo, Tak Yeung Leung, K.C. Allen Chan, Jiaen Deng, Lu Ji, Rossa W.K. Chiu
Publikováno v:
Clinical Chemistry. 67:788-796
Background Although the characterization of cell-free extrachromosomal circular DNA (eccDNA) has gained much research interest, the methylation status of these molecules is yet to be elucidated. We set out to compare the methylation densities of plas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8510193de5772014ffa83590571fa981
https://doi.org/10.1093/clinchem/hvaa326
https://doi.org/10.1093/clinchem/hvaa326
Autor:
K.C. Allen Chan, Tak Yeung Leung, Jiaen Deng, Rossa W.K. Chiu, Y.M. Dennis Lo, Peiyong Jiang, Anindya Dutta, Suk Hang Cheng, Sarah T K Sin, Lu Ji
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We observed the presence of extrachromosomal circular DNA (eccDNA) in the plasma of pregnant women. We found that the plasma eccDNA molecules were longer than their linear counterparts. Among such eccDNA molecules, those of fetal origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f92f5ad868aa79b82107eedb2095df
https://doi.org/10.1073/pnas.1914949117
https://doi.org/10.1073/pnas.1914949117
Autor:
Sarah T.K. Sin, Jiaen Deng, Lu Ji, Masashi Yukawa, Rebecca W.Y. Chan, Stefano Volpi, Augusto Vaglio, Paride Fenaroli, Paola Bocca, Suk Hang Cheng, Danny K.L. Wong, Kathy O. Lui, Peiyong Jiang, K.C. Allen Chan, Rossa W.K. Chiu, Y.M. Dennis Lo
Publikováno v:
JCI insight. 7(8)
Cell-free extrachromosomal circular DNA (eccDNA) as a distinct topological form from linear DNA has recently gained increasing research interest, with possible clinical applications as a class of biomarkers. In this study, we aimed to explore the rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df21e2344af1de422dee7e63e9fc29f
https://pubmed.ncbi.nlm.nih.gov/35451374
https://pubmed.ncbi.nlm.nih.gov/35451374
Autor:
Chou Yang, Deke Jiang, Changzheng Dong, S. Lilly Zheng, Xiaolong Qi, Irene Oi-Lin Ng, Yuan Ji, Qianyi Xiao, Jianfeng Xu, Jinlin Hou, Lin Wei, Bin Zhou, Pak C. Sham, Carly Conran, Long Yu, Miaoxin Li, Xiao-Pin Ma, Jiaen Deng, Guangwen Cao
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Background Recent genome-wide association studies (GWASs) have suggested several susceptibility loci of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) by statistical analysis at individual single-nucleotide polymorphisms (SNPs). Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af00dc312a9041aceb7a856bf9aad08
http://europepmc.org/articles/PMC7216662
http://europepmc.org/articles/PMC7216662
Autor:
Jiang, Deke, Jiaen Deng, Changzheng Dong, Xiaopin Ma, Qianyi Xiao, Zhou, Bin, Chou Yang, Wei, Lin, Conran, Carly, S. Lilly Zheng, Ng, Irene Oi-Lin, Yu, Long, Jianfeng Xu, Pak C. Sham, Xiaolong Qi, Jinlin Hou, Ji, Yuan, Guangwen Cao, Miaoxin Li
Additional file 1: Supplementary Figure 1. Manhattan plots of p-values of 5,375,073 SNPs obtained by a meta-analysis of two HBV-related HCC GWASs in Chinese populations. Supplementary Figure 2. The quantile-quantile plots of p-values of 5,375,073 SNP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd2f885dd630c79304e62b9e34f80c5
Autor:
Xiaolong Qi, S. Lilly Zheng, Guangwen Cao, Qianyi Xiao, Xiao-Pin Ma, Deke Jiang, Long Yu, Carly Conran, Lin Wei, Pak C. Sham, Chou Yang, Jinlin Hou, Jianfeng Xu, Bin Zhou, Changzheng Dong, Miaoxin Li, Jiaen Deng, Yuan Ji, Irene Oi-Lin Ng
Background : Recent genome-wide association studies (GWASs) have suggested several susceptibility loci of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) by statistical analysis at individual single-nucleotide polymorphisms (SNPs). How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766364c3fa4045e3ca6206a009fc15b3
https://doi.org/10.21203/rs.2.14627/v2
https://doi.org/10.21203/rs.2.14627/v2