Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jiachun Hu"'
Autor:
Chao Liu, Wei Liu, Yanhong Liu, Hongxia Duan, Liqing Chen, Xintong Zhang, Mingji Jin, Minhu Cui, Xiuquan Quan, Libin Pan, Jiachun Hu, Zhonggao Gao, Yan Wang, Wei Huang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 8, Pp 3425-3443 (2023)
The extremely low bioavailability of oral paclitaxel (PTX) mainly due to the complicated gastrointestinal environment, the obstruction of intestinal mucus layer and epithelium barrier. Thus, it is of great significance to construct a coordinative del
Externí odkaz:
https://doaj.org/article/91dedc090018415da3038bfcb148503a
Autor:
Libin Pan, Hang Yu, Jie Fu, Jiachun Hu, Hui Xu, Zhengwei Zhang, Mengmeng Bu, Xinyu Yang, Haojian Zhang, Jinyue Lu, Jiandong Jiang, Yan Wang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1537-1553 (2023)
At present, clinical interventions for chronic kidney disease are very limited, and most patients rely on dialysis to sustain their lives for a long time. However, studies on the gut–kidney axis have shown that the gut microbiota is a potentially e
Externí odkaz:
https://doaj.org/article/cff39d6275dd427e964afff0e46fb858
Autor:
Jingyue Wang, Xianfeng Zhang, Xinyu Yang, Hang Yu, Mengmeng Bu, Jie Fu, Zhengwei Zhang, Hui Xu, Jiachun Hu, Jinyue Lu, Haojian Zhang, Zhao Zhai, Wei Yang, Xiaodan Wu, Yan Wang, Qian Tong
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Numerous studies have demonstrated that gut microbiota plays an important role in the development and treatment of different cardiovascular diseases, including hypertension, heart failure, myocardial infarction, arrhythmia, and atherosclerosis. Furth
Externí odkaz:
https://doaj.org/article/69a8d591f6694bb18d02765fc8b7257c
Publikováno v:
Molecules, Vol 28, Iss 22, p 7575 (2023)
Gentiopicrin, the main component of the famous Chinese patent medicine Long Dan Xie Gan Wan, has the characteristics of fast absorption in vivo and low bioavailability. Intestinal bacteria play an important role in the absorption and pharmacokinetics
Externí odkaz:
https://doaj.org/article/0fe9030bf34a4d468eade9107b12e1b4
Autor:
Shuhua He, Xiang Gu, Jintong Yang, Fei Xu, Jiachun Hu, Wei Wang, Yiheng Huang, Bin Lou, Tingbo Ding, Lu Zhou, Deyong Ye, Ker Yu, Jibin Dong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Tumor-associated macrophages (TAMs) are one of the most abundant immune cells in the pancreatic cancer stroma and are related to the poor prognosis of pancreatic ductal adenocarcinoma (PDAC) patients. Therefore, targeting tumor-associated
Externí odkaz:
https://doaj.org/article/f6326105ed07431dafd7f7c6b77fed06
Autor:
Xinming Du, Jiachun Hu, Qing Zhang, Qi Liu, Xinxin Xiang, Jibin Dong, Bin Lou, Shuhua He, Xiang Gu, Yu Cao, Yingxia Li, Tingbo Ding
Publikováno v:
FEBS Open Bio, Vol 9, Iss 10, Pp 1734-1743 (2019)
Lysophosphatidylcholine acyltransferase 3 (LPCAT3) is an important enzyme in phospholipid remodeling, a process that influences the biophysical properties of cell membranes and thus cell function. Multiple lines of evidence suggest that LPCAT3 is inv
Externí odkaz:
https://doaj.org/article/8d9cce87883a426c923752a9ac468e01
Publikováno v:
Acta Biochimica et Biophysica Sinica.
Phosphatidylcholines (PCs) are major phospholipids in the mammalian cell membrane. Structural remodeling of PCs is associated with many biological processes. Lysophosphatidylcholine acyltransferase 3 (Lpcat3), which catalyzes the incorporation of pol
Publikováno v:
Building and Environment. 227:109791
Publikováno v:
Acta Biochimica et Biophysica Sinica; Jan2023, Vol. 55 Issue 1, p117-130, 14p
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundOsteoporosis is a major health issue. MicroRNAs (miRNAs) play multiple roles in regulating cell growth and development. High-throughput sequencing technology is widely used nowadays.ObjectiveTo screen for and validate miRNAs associated with
Externí odkaz:
https://doaj.org/article/e0d6337fb2d443d5954498a0b2ed051a